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Accurate quantification of metabolites in magnetic resonance spectroscopy (MRS) is challenged by low signal-to-noise ratio (SNR), overlapping metabolites, and various artifacts. Particularly, unknown and unparameterized baseline effects…

Signal Processing · Electrical Eng. & Systems 2024-10-15 Julian P. Merkofer , Dennis M. J. van de Sande , Sina Amirrajab , Kyung Min Nam , Ruud J. G. van Sloun , Alex A. Bhogal

We propose a novel dual-loop system that synergistically combines responsive neurostimulation (RNS) implants with artificial intelligence-driven wearable devices for treating post-traumatic stress disorder (PTSD) and enabling naturalistic…

Neurons and Cognition · Quantitative Biology 2025-03-25 Edward Hong Wang , Cynthia Xin Wen

The application of closed-loop approaches in systems neuroscience and therapeutic stimulation holds great promise for revolutionizing our understanding of the brain and for developing novel neuromodulation therapies to restore lost…

Signal Processing · Electrical Eng. & Systems 2021-10-12 Bingzhao Zhu , Uisub Shin , Mahsa Shoaran

Neuromodulation techniques have emerged as promising approaches for treating a wide range of neurological disorders, precisely delivering electrical stimulation to modulate abnormal neuronal activity. While leveraging the unique…

Mental disorders (MD) are among the top most demanding challenges in world-wide health. According to the World Health Organization, the burden of MDs continues to grow with significant impact on health and major social and human rights. A…

Neurons and Cognition · Quantitative Biology 2023-03-21 Thomas Wahl , Joséphine Riedinger , Michel Duprez , Axel Hutt

Stay at home order during the COVID-19 helps flatten the curve but ironically, instigate mental health problems among the people who have Substance Use Disorders. Measuring the electrical activity signals in brain using off-the-shelf…

Human-Computer Interaction · Computer Science 2022-04-15 Emon Dey , Nirmalya Roy

WiFi sensing has suffered from the limited bandwidths designated for its original communication purpose, leading to fundamental limits in multipath resolution and thus multi-user sensing. Unfortunately, it is practically prohibitive to…

Signal Processing · Electrical Eng. & Systems 2026-01-13 Sijie Ji , Weiying Hou , Chenshu Wu

Mental disorders may exhibit pathological brain rhythms and neurostimulation promises to alleviate of patients' symptoms by modifying these rhythms. Today, most neurostimulation schemes are open-loop, i.e. administer experimental…

Neurons and Cognition · Quantitative Biology 2023-03-21 Thomas Wahl , Michel Duprez , Axel Hutt

In this work, we simulate the functionality of artificial neuron and synapse using spin-orbit torque-based spintronic devices and implemented a fully connected artificial neural netwrok (ANN). These neuro-synaptic devices are emulated using…

Mesoscale and Nanoscale Physics · Physics 2026-05-22 Sakshi Kiran Bandekar , Arnab Ganguly , Debanjan Polley , Debasis Das

Closed-loop brain stimulation refers to capturing neurophysiological measures such as electroencephalography (EEG), quickly identifying neural events of interest, and producing auditory, magnetic or electrical stimulation so as to interact…

Signal Processing · Electrical Eng. & Systems 2022-10-12 Nicolas Valenchon , Yann Bouteiller , Hugo R. Jourde , Xavier L'Heureux , Milo Sobral , Emily B. J. Coffey , Giovanni Beltrame

In recent years, numerous research efforts have been dedicated towards developing efficient implantable devices for brain stimulation. However, there are limitations and challenges with the current technologies. Firstly, the stimulation of…

Closed-loop neural interfaces with on-chip machine learning can detect and suppress disease symptoms in neurological disorders or restore lost functions in paralyzed patients. While high-density neural recording can provide rich neural…

Signal Processing · Electrical Eng. & Systems 2023-03-21 Uisub Shin , Cong Ding , Bingzhao Zhu , Yashwanth Vyza , Alix Trouillet , Emilie C. M. Revol , Stéphanie P. Lacour , Mahsa Shoaran

In recent years, there has been a growing interest in exploring the application of single-photon avalanche diode (SPAD) in optical wireless communication (OWC). As a photon counting detector, SPAD can provide much higher sensitivity…

Information Theory · Computer Science 2022-02-14 Shenjie Huang , Majid Safari

Neural networks modularity is a major challenge for the development of control circuits of neural activity. Under physiological limitations, the accessible regions for external stimulation are possibly different from the functionally…

Neurons and Cognition · Quantitative Biology 2018-02-23 Hanna Keren , Johannes Partzsch , Shimon Marom , Christian Mayr

Various intervention therapies ranging from pharmaceutical to hi-tech tailored solutions have been available to treat difficulty in falling asleep commonly caused by insomnia in modern life. However, current techniques largely remain…

Systems and Control · Electrical Eng. & Systems 2022-11-07 Anh Nguyen , Galen Pogoncheff , Ban Xuan Dong , Nam Bui , Hoang Truong , Nhat Pham , Linh Nguyen , Hoang Huu Nguyen , Sy Duong-Quy , Sangtae Ha , Tam Vu

We present ClearBuds, the first hardware and software system that utilizes a neural network to enhance speech streamed from two wireless earbuds. Real-time speech enhancement for wireless earbuds requires high-quality sound separation and…

In the intact brain, neural activity can be recorded using sensing electrodes and manipulated using light stimulation. Silicon probes with integrated electrodes and micro-LEDs enable the detection and control of neural activity using a…

Signal Processing · Electrical Eng. & Systems 2022-11-28 Alexander Tarnavsky Eitan , Shirly Someck , Mario Zajac , Eran Socher , Eran Stark

We investigate the use of musically structured, closed-loop vibration patterns as a passive biofeedback intervention for relaxation and sleep initiation. By encoding rhythmic meter structures into smartwatch vibrations and adapting their…

Human-Computer Interaction · Computer Science 2025-07-04 Jueun Lee , Dennis Moschina , Supraja Ramesh , Tobias Röddiger , Kai Kunze , Michael Beigl

We are proposing fully parallel and maximally distributed hardware realization of a generic neuro-computing system. More specifically, the proposal relates to the wireless sensor networks technology to serve as a massively parallel and…

Neural and Evolutionary Computing · Computer Science 2025-10-31 Gursel Serpen

High density neurostimulation systems are coming to market to help spinal cord injury patients by stimulating and recording neuromuscular function. However, the parameter space that these systems have to explore is exceedingly large, and…

Signal Processing · Electrical Eng. & Systems 2021-12-06 Dhruv Pai , Mentor Kip Ludwig
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