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The proposed stochastic model for pedestrian dynamics is based on existing approaches using cellular automata, combined with substantial extensions, to compensate the deficiencies resulting of the discrete grid structure. This agent motion…

Physics and Society · Physics 2021-04-01 Michael Schultz

Collective cell migration is a key driver of embryonic development, wound healing, and some types of cancer invasion. Here we provide a physical perspective of the mechanisms underlying collective cell migration. We begin with a catalogue…

Biological Physics · Physics 2019-10-08 Ricard Alert , Xavier Trepat

The transport equation of active motion is generalised to consider time-fractional dynamics for describing the anomalous diffusion of self-propelled particles observed in many different systems. In the present study, we consider an…

Statistical Mechanics · Physics 2023-10-27 Francisco J. Sevilla , Guillermo Chacón-Acosta , Trifce Sandev

We study heat transport in a one-dimensional chain of a finite number $N$ of identical cells, coupled at its boundaries to stochastic particle reservoirs. At the center of each cell, tracer particles collide with fixed scatterers,…

Statistical Mechanics · Physics 2022-04-10 Pierre Collet , Jean-Pierre Eckmann , Carlos Mejia-Monasterio

Cells move differently on substrates with different elasticities. In particular, the persistence time of their motion is higher on stiffer substrates. We show that this behavior will result in a net transport of cells directed up a…

Biological Physics · Physics 2017-03-09 Elizaveta A. Novikova , Matthew Raab , Dennis E. Discher , Cornelis Storm

Increasing evidence suggests that active matter exhibits instances of mixed symmetry that cannot be fully described by either polar or nematic formalism. Here, we introduce a minimal model that integrates self-propulsion into the active…

Soft Condensed Matter · Physics 2025-09-03 Niels de Graaf Sousa , Simon Guldager Andersen , Aleksandra Ardaševa , Amin Doostmohammadi

The crossover between dispersion patterns has been frequently observed in various systems. Inspired by the pathway-based kinetic model for E. coli chemotaxis that accounts for the intracellular adaptation process and noise, we propose a…

Analysis of PDEs · Mathematics 2025-01-07 Zhe Xue , Weiran Sun , Zhennan Zhou , Min Tang

Non-typical transport phenomena may arise when randomly driven particles remain in an active relationship with the environment instead of being passive. If we attribute to Brownian particles an ability to induce alterations of the…

Statistical Mechanics · Physics 2009-10-31 Piotr Garbaczewski

In the absence of environmental cues, a migrating cell performs an isotropic random motion. Recently, the breaking of this isotropy has been observed when cells move in the presence of asymmetric adhesive patterns. However, up to now the…

Soft Condensed Matter · Physics 2015-06-17 M. Le Berre , Yan-Jun Liu , J. Hu , P. Maiuri , O. Bénichou , R. Voituriez , Y. Chen , M. Piel

Many diffusion processes in nature and society were found to be anomalous, in the sense of being fundamentally different from conventional Brownian motion. An important example is the migration of biological cells, which exhibits…

Statistical Mechanics · Physics 2018-02-13 J. M. Nava-Sedeno , H. Hatzikirou , R. Klages , A. Deutsch

Motile biological cells in tissue often display the phenomenon of durotaxis, i.e. they tend to move towards stiffer parts of substrate tissue. The mechanism for this behavior is not completely understood. We consider simplified models for…

Biological Physics · Physics 2019-01-03 Charles R. Doering , Xiaoming Mao , Leonard M. Sander

The motion of molecules across channels is critically important for understanding mechanisms of cellular processes. Here we investigate the mechanism of interactions in the molecular transport by analyzing exactly solvable discrete…

Soft Condensed Matter · Physics 2015-05-18 Anatoly B. Kolomeisky , Karthik Uppulury

Kinetic constraints are generally expected to slow down dynamics in many-body systems, obstructing or even completely suppressing transport of conserved charges. Here, we show how gauge theories can defy this wisdom by yielding constrained…

Thermal motion in complex fluids is a complicated stochastic process but ubiquitously exhibits initial ballistic, intermediate sub-diffusive, and long-time non-Gaussian diffusive motion, unless interrupted. Despite its relevance to numerous…

Disordered Systems and Neural Networks · Physics 2019-09-04 Sanggeun Song , Seong Jun Park , Bong June Sung , Jun Soo Kim , Ji-Hyun Kim , Jaeyoung Sung

Transport at microscopic length scales is essential in biological systems and various technologies, including microfluidics. Recent experiments achieved self-organized transport phenomena in microtubule active matter using light to modulate…

Soft Condensed Matter · Physics 2021-08-02 Dominik Schildknecht , Matt Thomson

Molecular motors are specialized proteins which perform active, directed transport of cellular cargoes on cytoskeletal filaments. In many cases, cargo motion powered by motor proteins is found to be bidirectional, and may be viewed as a…

Subcellular Processes · Quantitative Biology 2015-06-16 Deepak Bhat , Manoj Gopalakrishnan

Active gels are a class of biologically-relevant material containing embedded agents that spontaneously generate forces acting on a sparse filament network. In vitro experiments of protein filaments and molecular motors have revealed a…

Soft Condensed Matter · Physics 2024-06-03 David A. Head , Gerhard Gompper , W. J. Briels

Cells can show not only spontaneous movement but also tactic responses to environmental signals. Since the former can be regarded as the basis to realize the latter, playing essential roles in various cellular functions, it is important to…

Cell Behavior · Quantitative Biology 2015-05-13 Hiroaki Takagi , Masayuki J. Sato , Toshio Yanagida , Masahiro Ueda

Epithelial-Mesenchymal Transition (EMT), and the corresponding reverse process, Mesenchymal-Epithelial Transition (MET), are dynamic and reversible cellular programs orchestrated by many changes at biochemical and morphological levels. A…

Molecular Networks · Quantitative Biology 2019-07-26 Shubham Tripathi , Jianhua Xing , Herbert Levine , Mohit Kumar Jolly

Self-generated gradients (SGG) provide robust steering cues that guide cells in their long-distance expeditions during embryonic development, immune response, and cancer metastasis. Cells generate their own local, dynamic gradients by…

Soft Condensed Matter · Physics 2021-09-29 Himadri S Samanta
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