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There are several indications that brain is organized not on a basis of individual unreliable neurons, but on a micro-circuital scale providing Lego blocks employed to create complex architectures. At such an intermediate scale, the firing…

Neural and Evolutionary Computing · Computer Science 2017-02-27 Ramin M. Hasani , Giorgio Ferrari , Hideaki Yamamoto , Sho Kono , Koji Ishihara , Soya Fujimori , Takashi Tanii , Enrico Prati

Spontaneous cortical population activity exhibits a multitude of oscillatory patterns, which often display synchrony during slow-wave sleep or under certain anesthetics and stay asynchronous during quiet wakefulness. The mechanisms behind…

Neurons and Cognition · Quantitative Biology 2018-06-20 Rodrigo F. O. Pena , Michael A. Zaks , Antonio C. Roque

For complex life to evolve, a sophisticated nervous system for handling its complexities was fundamental. The demand resulted in the emergence of brain's computational facility, the neuronal network. This facet of the brain is attested…

Neurons and Cognition · Quantitative Biology 2019-09-16 Jahan N. Schad

Chaos and Noise are ubiquitous in the Brain. Inspired by the chaotic firing of neurons and the constructive role of noise in neuronal models, we for the first time connect chaos, noise and learning. In this paper, we demonstrate Stochastic…

Neurons and Cognition · Quantitative Biology 2021-03-10 Harikrishnan NB , Nithin Nagaraj

Similar to intelligent multicellular neural networks controlling human brains, even single cells surprisingly are able to make intelligent decisions to classify several external stimuli or to associate them. This happens because of the fact…

Molecular Networks · Quantitative Biology 2018-11-21 Russell Bates , Oleg Blyuss , Ahmed Alsaedi , Alexey Zaikin

Natural and artificial networks, from the cerebral cortex to large-scale power grids, face the challenge of converting noisy inputs into robust signals. The input fluctuations often exhibit complex yet statistically reproducible…

Adaptation and Self-Organizing Systems · Physics 2018-11-19 Henrik Ronellenfitsch , Jörn Dunkel , Michael Wilczek

Stochasticity (or noise) at cellular and molecular levels has been observed extensively as a universal feature for living systems. However, how living systems deal with noise while performing desirable biological functions remains a major…

Molecular Networks · Quantitative Biology 2020-01-22 Qing Nie , Lingxia Qiao , Yuchi Qiu , Lei Zhang , Wei Zhao

Synchronization is a widespread phenomenon observed in physical, biological, and social networks, which persists even under the influence of strong noise. Previous research on oscillators subject to common noise has shown that noise can…

Adaptation and Self-Organizing Systems · Physics 2021-06-02 Zachary G. Nicolaou , Michael Sebek , Istvan Z. Kiss , Adilson E. Motter

The nervous system displays a variety of rhythms in both waking and sleep. These rhythms have been closely associated with different behavioral and cognitive states, but it is still unknown how the nervous system makes use of these rhythms…

Dynamical Systems · Mathematics 2007-05-23 Nancy Kopell

The brain is a highly complex organ consisting of a myriad of subsystems that flexibly interact and adapt over time and context to enable perception, cognition, and behavior. Understanding the multi-scale nature of the brain, i.e., how…

Neurons and Cognition · Quantitative Biology 2025-01-17 Adam S. Charles

Neocortical neurons have thousands of excitatory synapses. It is a mystery how neurons integrate the input from so many synapses and what kind of large-scale network behavior this enables. It has been previously proposed that non-linear…

Neurons and Cognition · Quantitative Biology 2016-04-25 Jeff Hawkins , Subutai Ahmad

Large networks of spiking neurons show abrupt changes in their collective dynamics resembling phase transitions studied in statistical physics. An example of this phenomenon is the transition from irregular, noise-driven dynamics to…

Adaptation and Self-Organizing Systems · Physics 2008-11-25 Vicenç Gómez , Andreas Kaltenbrunner , Vicente López , Hilbert J. Kappen

Multiscale modelling presents a multifaceted perspective into understanding the mechanisms of the brain and how neurodegenerative disorders like Parkinson's disease (PD) manifest and evolve over time. In this study, we propose a novel…

Neurons and Cognition · Quantitative Biology 2025-09-18 Aaron Herrera , Hina Shaheen

Neuromorphic computing, inspired by the brain, promises extreme efficiency for certain classes of learning tasks, such as classification and pattern recognition. The performance and power consumption of neuromorphic computing depends…

Emerging Technologies · Computer Science 2018-06-14 Baibhab Chatterjee , Priyadarshini Panda , Shovan Maity , Ayan Biswas , Kaushik Roy , Shreyas Sen

The response of neurons is highly sensitive to the stimulus. The stimulus can be associated with a direct injection in vitro experimentation (e.g., time dependent and independent inputs); or post-synaptic potentials resulting from the…

Neurons and Cognition · Quantitative Biology 2024-01-09 Afifurrahman , Mohd Hafiz Mohd , Farah Aini Abdullah

The highly irregular spiking activity of cortical neurons and behavioral variability suggest that the brain could operate in a fundamentally probabilistic way. Mimicking how the brain implements and learns probabilistic computation could be…

Neural and Evolutionary Computing · Computer Science 2024-04-23 Yang Qi , Zhichao Zhu , Yiming Wei , Lu Cao , Zhigang Wang , Jie Zhang , Wenlian Lu , Jianfeng Feng

We propose a new non-equilibrium model for spatial pattern formation on the basis of local information transfer. Unlike standard models of pattern formation it is not based on the Turing instability. Information is transmitted through the…

Statistical Mechanics · Physics 2007-05-23 Thimo Rohlf , Stefan Bornholdt

We propose a novel discrete model of central pattern generators (CPG), neuronal ensembles generating rhythmic activity. The model emphasizes the role of nonsynaptic interactions and the diversity of electrical properties in nervous systems.…

Neural and Evolutionary Computing · Computer Science 2017-05-10 Nikolay Bazenkov , Varvara Dyakonova , Oleg Kuznetsov , Dmitri Sakharov , Dmitry Vorontsov , Liudmila Zhilyakova

The rapid evolution of artificial intelligence (AI) has shifted from static, data-driven models to dynamic systems capable of perceiving and interacting with real-world environments. Despite advancements in pattern recognition and symbolic…

Neocortical pyramidal neurons have many dendrites, and such dendrites are capable of, in isolation of one-another, generating a neuronal spike. It is also now understood that there is a large amount of dendritic growth during the first…

Neurons and Cognition · Quantitative Biology 2022-10-31 William B Levy , Robert A. Baxter
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