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In breast cancer, neoadjuvant chemotherapy (NAC) provides a standard treatment option for patients who have locally advanced cancer and some large operable tumors. A patient will have better prognosis when he has achieved a pathological…

Medical Physics · Physics 2024-11-12 Yongquan Yang , Fengling Li , Yani Wei , Yuanyuan Zhao , Jing Fu , Xiuli Xiao , Hong Bu

Managing patients with chronic diseases is a major and growing healthcare challenge in several countries. A chronic condition, such as diabetes, is an illness that lasts a long time and does not go away, and often leads to the patient's…

Machine Learning · Computer Science 2020-03-23 Rafael T. Sousa , Lucas A. Pereira , Anderson S. Soares

In medicine, both ethical and monetary costs of incorrect predictions can be significant, and the complexity of the problems often necessitates increasingly complex models. Recent work has shown that changing just the random seed is enough…

Cardiovascular diseases (CVDs) encompass a group of disorders affecting the heart and blood vessels, including conditions such as coronary artery disease, heart failure, stroke, and hypertension. In cardiovascular diseases, heart failure is…

Artificial Intelligence · Computer Science 2024-07-12 Ershadul Haque , Manoranjan Paul , Faranak Tohidi

Contrastive learning has demonstrated promising performance in image and text domains either in a self-supervised or a supervised manner. In this work, we extend the supervised contrastive learning framework to clinical risk prediction…

Machine Learning · Computer Science 2021-10-12 Chengxi Zang , Fei Wang

Deep learning models have shown tremendous potential in learning representations, which are able to capture some key properties of the data. This makes them great candidates for transfer learning: Exploiting commonalities between different…

In a data-scarce field such as healthcare, where models often deliver predictions on patients with rare conditions, the ability to measure the uncertainty of a model's prediction could potentially lead to improved effectiveness of decision…

Machine Learning · Statistics 2020-05-26 Lotta Meijerink , Giovanni Cinà , Michele Tonutti

Clinical prediction from structured electronic health records (EHRs) is challenging due to high dimensionality, heterogeneity, class imbalance, and distribution shift. While tabular in-context learning (TICL) and retrieval-augmented methods…

Widespread adoption of AI for medical decision making is still hindered due to ethical and safety-related concerns. For AI-based decision support systems in healthcare settings it is paramount to be reliable and trustworthy. Common deep…

Machine Learning · Computer Science 2024-01-26 Adrian Lindenmeyer , Malte Blattmann , Stefan Franke , Thomas Neumuth , Daniel Schneider

The growing availability of well-organized Electronic Health Records (EHR) data has enabled the development of various machine learning models towards disease risk prediction. However, existing risk prediction methods overlook the…

Machine Learning · Computer Science 2024-06-17 Ziyang Zhang , Hejie Cui , Ran Xu , Yuzhang Xie , Joyce C. Ho , Carl Yang

Confidence region prediction is a practically useful extension to the commonly studied pattern recognition problem. Instead of predicting a single label, the constraint is relaxed to allow prediction of a subset of labels given a desired…

Machine Learning · Computer Science 2024-05-27 David Lindsay , Sian Lindsay

Chronic kidney disease (CKD) is a gradual loss of renal function over time, and it increases the risk of mortality, decreased quality of life, as well as serious complications. The prevalence of CKD has been increasing in the last couple of…

Machine Learning · Computer Science 2020-11-18 Jinghe Zhang , Kamran Kowsari , Mehdi Boukhechba , James Harrison , Jennifer Lobo , Laura Barnes

Forecasting healthcare time series data is vital for early detection of adverse outcomes and patient monitoring. However, it can be challenging in practice due to variable medication administration and unique pharmacokinetic (PK) properties…

Machine Learning · Computer Science 2025-12-17 Willa Potosnak , Cristian Challu , Kin G. Olivares , Keith A. Dufendach , Artur Dubrawski

Interest in targeted disease prevention has stimulated development of models that assign risks to individuals, using their personal covariates. We need to evaluate these models, and to quantify the gains achieved by expanding a model with…

Methodology · Statistics 2009-06-16 Alice S. Whittemore

Quantifying uncertainty in clinical predictions is critical for high-stakes diagnosis tasks. Conformal prediction offers a principled approach by providing prediction sets with theoretical coverage guarantees. However, in practice, patient…

Machine Learning · Computer Science 2026-05-01 Arjun Chatterjee , Sayeed Sajjad Razin , John Wu , Siddhartha Laghuvarapu , Jathurshan Pradeepkumar , Jimeng Sun

While deep learning has shown promise in the domain of disease classification from medical images, models based on state-of-the-art convolutional neural network architectures often exhibit performance loss due to dataset shift. Models…

Machine Learning · Computer Science 2020-01-14 Joseph D. Janizek , Gabriel Erion , Alex J. DeGrave , Su-In Lee

Early prediction of mortality and length of stay(LOS) of a patient is vital for saving a patient's life and management of hospital resources. Availability of electronic health records(EHR) makes a huge impact on the healthcare domain and…

Machine Learning · Computer Science 2020-12-01 Batuhan Bardak , Mehmet Tan

Improving the quality of end-of-life care for hospitalized patients is a priority for healthcare organizations. Studies have shown that physicians tend to over-estimate prognoses, which in combination with treatment inertia results in a…

Computers and Society · Computer Science 2017-11-20 Anand Avati , Kenneth Jung , Stephanie Harman , Lance Downing , Andrew Ng , Nigam H. Shah

In large epidemiologic studies, it is typical for an inexpensive, non-invasive procedure to be used to record disease status during regular follow-up visits, with less frequent assessment by a gold standard test. Inexpensive outcome…

Methodology · Statistics 2022-09-22 Lillian A. Boe , Pamela A. Shaw

Stroke affected millions annually, yet poor symptom recognition often delayed care-seeking. To address risk recognition gap, we developed a passive surveillance system for early stroke risk detection using patient-reported symptoms among…