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The identification of homologous gene families across multiple genomes is a central task in bacterial pangenomics traditionally requiring computationally demanding all-against-all comparisons. PanDelos addresses this challenge with an…

Genomics · Quantitative Biology 2025-10-29 Simone Colli , Emiliano Maresi , Vincenzo Bonnici

The introduction of accelerator devices such as graphics processing units (GPUs) has had profound impact on molecular dynamics simulations and has enabled order-of-magnitude performance advances using commodity hardware. To fully reap these…

Computational Physics · Physics 2020-10-28 Szilárd Páll , Artem Zhmurov , Paul Bauer , Mark Abraham , Magnus Lundborg , Alan Gray , Berk Hess , Erik Lindahl

Click-through rate (CTR) prediction, which models behavior sequence and non-sequential features (e.g., user/item profiles or cross features) to infer user interest, underpins industrial recommender systems. However, most methods face three…

Information Retrieval · Computer Science 2025-10-24 Shuwei Chen , Jiajun Cui , Zhengqi Xu , Fan Zhang , Jiangke Fan , Teng Zhang , Xingxing Wang

Top-K SpMV is a key component of similarity-search on sparse embeddings. This sparse workload does not perform well on general-purpose NUMA systems that employ traditional caching strategies. Instead, modern FPGA accelerator cards have a…

Hardware Architecture · Computer Science 2021-03-09 Alberto Parravicini , Luca Giuseppe Cellamare , Marco Siracusa , Marco Domenico Santambrogio

With the increasing time and frequency resolution of modern radio telescopes and the exponential growth in observational data volumes, real-time single-pulse detection has become a critical requirement for time-domain radio astronomy.…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-02 Bingzheng Xia , Zujie Ren , Kuang Ma , Xiaoqian Li , Wenda Li , Shuibing He

Computational complexity is a key limitation of genomic analyses. Thus, over the last 30 years, researchers have proposed numerous fast heuristic methods that provide computational relief. Comparing genomic sequences is one of the most…

This paper presents a Graphics Processing Units (GPUs) acceleration method of an iterative scheme for gas-kinetic model equations. Unlike the previous GPU parallelization of explicit kinetic schemes, this work features a fast converging…

Computational Physics · Physics 2020-01-08 Lianhua Zhu , Peng Wang , Songze Chen , Zhaoli Guo , Yonghao Zhang

Parallel computing is a standard approach to achieving high-performance computing (HPC). Three commonly used methods to implement parallel computing include: 1) applying multithreading technology on single-core or multi-core CPUs; 2)…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-09-18 Xinyao Yi

The increasing use of heterogeneous embedded systems with multi-core CPUs and Graphics Processing Units (GPUs) presents important challenges in effectively exploiting pipeline, task and data-level parallelism to meet throughput requirements…

Signal Processing · Electrical Eng. & Systems 2017-12-01 Shuoxin Lin , Jiahao Wu , Shuvra S. Bhattacharyya

Molecular similarity search has been widely used in drug discovery to identify structurally similar compounds from large molecular databases rapidly. With the increasing size of chemical libraries, there is growing interest in the efficient…

Hardware Architecture · Computer Science 2021-09-15 Hongwu Peng , Shiyang Chen , Zhepeng Wang , Junhuan Yang , Scott A. Weitze , Tong Geng , Ang Li , Jinbo Bi , Minghu Song , Weiwen Jiang , Hang Liu , Caiwen Ding

Database search and clustering are fundamental components of many data analytics problems, such as mass spectrometry-driven proteomics. Traditional full clustering and search algorithms suffer from high resource usage and long latencies. We…

Databases · Computer Science 2025-11-25 Md Mizanur Rahaman Nayan , Zheyu Li , Flavio Ponzina , Sumukh Pinge , Tajana Rosing , Azad J. Naeemi

Neural network training entails heavy computation with obvious bottlenecks. The Compute Unified Device Architecture (CUDA) programming model allows us to accelerate computation by passing the processing workload from the CPU to the graphics…

Machine Learning · Computer Science 2019-08-22 Sterling Ramroach , Andrew Dhanoo , Brian Cockburn , Ajay Joshi

Today, there are a plethora of In-Memory Computing (IMC) devices- SRAMs, PCMs & FeFETs, that emulate convolutions on crossbar-arrays with high throughput. Each IMC device offers its own pros & cons during inference of Deep Neural Networks…

Emerging Technologies · Computer Science 2023-10-25 Abhiroop Bhattacharjee , Abhishek Moitra , Priyadarshini Panda

I present HPRMAT, a high-performance solver library for the linear systems arising in R-matrix coupled-channel scattering calculations in nuclear physics. Designed as a drop-in replacement for the linear algebra routines in existing…

Computational Physics · Physics 2025-12-15 Jin Lei

Mixed-precision neural network (MPNN) that utilizes just enough data width for the neural network processing is an effective approach to meet the stringent resources constraints including memory and computing of MCUs. Nevertheless, there is…

Hardware Architecture · Computer Science 2024-07-29 Junfeng Gong , Cheng Liu , Long Cheng , Huawei Li , Xiaowei Li

Graph Convolutional Neural Network (GCNN) is a popular class of deep learning (DL) models in material science to predict material properties from the graph representation of molecular structures. Training an accurate and comprehensive GCNN…

Machine Learning · Computer Science 2022-07-26 Jong Youl Choi , Pei Zhang , Kshitij Mehta , Andrew Blanchard , Massimiliano Lupo Pasini

Heterogeneous graph neural networks (HGNNs) have emerged as powerful algorithms for processing heterogeneous graphs (HetGs), widely used in many critical fields. To capture both structural and semantic information in HetGs, HGNNs first…

Hardware Architecture · Computer Science 2024-04-29 Runzhen Xue , Dengke Han , Mingyu Yan , Mo Zou , Xiaocheng Yang , Duo Wang , Wenming Li , Zhimin Tang , John Kim , Xiaochun Ye , Dongrui Fan

Accelerating Human Action Recognition (HAR) efficiently for real-time surveillance and robotic systems on edge chips remains a challenging research field, given its high computational and memory requirements. This paper proposed an…

Computer Vision and Pattern Recognition · Computer Science 2023-11-08 Azzam Alhussain , Mingjie Lin

Computational intensity and sequential nature of estimation techniques for Bayesian methods in statistics and machine learning, combined with their increasing applications for big data analytics, necessitate both the identification of…

Computation · Statistics 2015-03-02 Alireza S. Mahani , Mansour T. A. Sharabiani

Sequence alignment is a fundamental process in computational biology which identifies regions of similarity in biological sequences. With the exponential growth in the volume of data in bioinformatics databases, the time, processing power,…

Hardware Architecture · Computer Science 2025-07-31 Nasrin Akbari , Mehdi Modarressi , Alireza Khadem