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The spatial transcriptomics (ST) data produced by recent biotechnologies, such as CosMx and Xenium, contain huge amount of information about cancer tissue samples, which has great potential for cancer research via detection of community: a…

Applications · Statistics 2025-07-01 Charles Zhao

Finding meaningful communities - subnetworks of interest within a large scale network - is a problem with a variety of applications. Most existing work towards community detection focuses on a single network. However, many real-life…

Social and Information Networks · Computer Science 2020-11-19 Dhara Shah , Yubao Wu , Sushil Prasad , Danial Aghajarian

Spatial networks are useful for modeling geographic phenomena where spatial interaction plays an important role. To analyze the spatial networks and their internal structures, graph-based methods such as community detection have been widely…

Social and Information Networks · Computer Science 2024-11-26 Yunlei Liang , Jiawei Zhu , Wen Ye , Song Gao

Community detection is considered as a fundamental task in analyzing social networks. Even though many techniques have been proposed for community detection, most of them are based exclusively on the connectivity structures. However, there…

Social and Information Networks · Computer Science 2019-12-25 Hadi Zare , Mahdi Hajiabadi , Mahdi Jalili

Hypergraph data appear and are hidden in many places in the modern age. They are data structure that can be used to model many real data examples since their structures contain information about higher order relations among data points. One…

Social and Information Networks · Computer Science 2020-10-02 Dong Quan Ngoc Nguyen , Lin Xing , Lizhen Lin

Dynamic community detection (DCD) in temporal networks is a complicated task that involves the selection of a method and its associated hyperparameters. How to choose the most appropriate method generally depends on the type of network…

Data Analysis, Statistics and Probability · Physics 2024-03-25 Bengier Ülgen Kilic , Sarah Feldt Muldoon

Recent chromosome conformation capture experiments have led to the discovery of dense, contiguous, megabase-sized topological domains that are similar across cell types and conserved across species. These domains are strongly correlated…

Quantitative Methods · Quantitative Biology 2013-07-31 Darya Filippova , Rob Patro , Geet Duggal , Carl Kingsford

Interacting, self-propelled particles such as epithelial cells can dynamically self-organize into complex multicellular patterns, which are challenging to classify without a priori information. Classically, different phases and phase…

Quantitative Methods · Quantitative Biology 2021-01-19 Dhananjay Bhaskar , William Y. Zhang , Ian Y. Wong

Exploring meaningful structural regularities embedded in networks is a key to understanding and analyzing the structure and function of a network. The node-attribute information can help improve such understanding and analysis. However,…

Social and Information Networks · Computer Science 2021-12-08 Wei Liu , Zhenhai Chang , Caiyan Jia , Yimei Zheng

Graph Anomaly Detection (GAD) has demonstrated great effectiveness in identifying unusual patterns within graph-structured data. However, while labeled anomalies are often scarce in emerging applications, existing supervised GAD approaches…

Machine Learning · Computer Science 2025-10-21 Delaram Pirhayati , Arlei Silva

Combining genome-wide structural models with phenomenological data is at the forefront of efforts to understand the organizational principles regulating the human genome. Here, we use chromosome-chromosome contact data as knowledge-based…

Biological Physics · Physics 2016-10-31 Marco Di Stefano , Jonas Paulsen , Tonje G. Lien , Eivind Hovig , Cristian Micheletti

Community detection is one of the most important and interesting issues in social network analysis. In recent years, simultaneous considering of nodes' attributes and topological structures of social networks in the process of community…

Social and Information Networks · Computer Science 2022-12-29 Ali Reihanian , Mohammad-Reza Feizi-Derakhshi , Hadi S. Aghdasi

Community detection is one of the most active fields in complex networks analysis, due to its potential value in practical applications. Many works inspired by different paradigms are devoted to the development of algorithmic solutions…

Social and Information Networks · Computer Science 2012-08-16 Günce Orman , Vincent Labatut , Hocine Cherifi

Understanding how the spatial structure of blood vessel networks relates to their function in healthy and abnormal biological tissues could improve diagnosis and treatment for diseases such as cancer. New imaging techniques can generate…

Quantitative Methods · Quantitative Biology 2019-07-23 Helen M Byrne , Heather A Harrington , Ruth Muschel , Gesine Reinert , Bernadette J Stolz , Ulrike Tillmann

Numerous networked systems feature a structure of nontrivial communities, which often correspond to their functional modules. Such communities have been detected in real-world biological, social and technological systems, as well as in…

Physics and Society · Physics 2025-07-08 Charo I. del Genio

Topological data analysis (TDA) is a branch of computational mathematics, bridging algebraic topology and data science, that provides compact, noise-robust representations of complex structures. Deep neural networks (DNNs) learn millions of…

A significant number of anomalous nodes in the real world, such as fake news, noncompliant users, malicious transactions, and malicious posts, severely compromises the health of the graph data ecosystem and urgently requires effective…

Machine Learning · Computer Science 2026-03-11 Xiong Zhang , Hong Peng , Changlong Fu , Xin Jin , Yun Yang , Cheng Xie

Topological Data Analysis (TDA) is an emergent field that aims to discover topological information hidden in a dataset. TDA tools have been commonly used to create filters and topological descriptors to improve Machine Learning (ML)…

Machine Learning · Computer Science 2022-02-07 Rolando Kindelan , José Frías , Mauricio Cerda , Nancy Hitschfeld

Topological representations are rapidly becoming a popular way to capture and encode higher-order interactions in complex systems. They have found applications in disciplines as different as cancer genomics, brain function, and…

Alzheimer's disease (AD) emerges from a complex interplay of molecular, cellular, and network-level disturbances that are not easily captured by traditional reductionist frameworks. Conventional analyses of gene expression often rely on…

Quantitative Methods · Quantitative Biology 2025-12-11 Aya Samadzelkava