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Despite super-resolution fluorescence blinking microscopes break the diffraction limit, the intense phototoxic illumination and long-term image sequences thus far still pose to major challenges in visualizing live-organisms. Here, we…

The recent use of diffusion prior, enhanced by pre-trained text-image models, has markedly elevated the performance of image super-resolution (SR). To alleviate the huge computational cost required by pixel-based diffusion SR, latent-based…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Feng Luo , Jinxi Xiang , Jun Zhang , Xiao Han , Wei Yang

Fast and sensitive detector arrays enable image scanning microscopy (ISM), overcoming the trade-off between spatial resolution and signal-to-noise ratio (SNR) typical of confocal microscopy. However, current ISM approaches cannot provide…

Diffusion model shows remarkable potential on sparse-view computed tomography (SVCT) reconstruction. However, when a network is trained on a limited sample space, its generalization capability may be constrained, which degrades performance…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Zekun Zhou , Tan Liu , Bing Yu , Yanru Gong , Liu Shi , Qiegen Liu

Super-resolution effects in optical and fluorescence biological systems are analyzed and their relations with uncertainty relations are discussed. Super-resolutions obtained in the optical systems, including especially NSOM, SIM and…

Optics · Physics 2015-06-12 Yacob Ben-Aryeh

Far-field optical microscopy using focused light is an important tool in a number of scientific disciplines including chemical, (bio)physical and biomedical research, particularly with respect to the study of living cells and organisms.…

Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the universal…

Fluorescence microscopy is indispensable in nanoscience and biological sciences. The versatility of labeling target structures with fluorescent dyes permits to visualize structure and function at a subcellular resolution with a wide field…

Far-field characterization of small objects is severely constrained by the diffraction limit. Existing tools achieving sub-diffraction resolution often utilize point-by-point image reconstruction via scanning or labelling. Here, we present…

We report a new coherent imaging technique, termed ptychographic structured modulation (PSM), for quantitative super-resolution microscopy. In this technique, we place a thin diffuser (i.e., a scattering lens) in between the sample and the…

Image and Video Processing · Electrical Eng. & Systems 2019-07-26 Pengming Song , Shaowei Jiang , He Zhang , Zichao Bian , Chengfei Guo , Kazunori Hoshino , Guoan Zheng

Sparsity constrained single image super-resolution (SR) has been of much recent interest. A typical approach involves sparsely representing patches in a low-resolution (LR) input image via a dictionary of example LR patches, and then using…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Hojjat S. Mousavi , Vishal Monga

Accurate land cover segmentation of spectral images is challenging and has drawn widespread attention in remote sensing due to its inherent complexity. Although significant efforts have been made for developing a variety of methods, most of…

Image and Video Processing · Electrical Eng. & Systems 2021-11-30 Carlos Hinojosa , Esteban Vera , Henry Arguello

In recent years several methods to overcome diffraction limit in the far field microscopy have been demonstrated. Still the problem of superresolution is reliably solved only for fluorescent microscopy, giving a resolution of up to 20-30nm.…

Optics · Physics 2013-09-03 Yu. V. Miklyaev , S. A. Asselborn , K. A. Zaytsev , M. Ya. Darscht

Fluorescence microscopy is a critical tool across various disciplines, from materials science to biomedical research, yet it is limited by the diffraction limit of resolution. Advanced super-resolution techniques such as localization…

Current CNN-based super-resolution (SR) methods process all locations equally with computational resources being uniformly assigned in space. However, since missing details in low-resolution (LR) images mainly exist in regions of edges and…

Computer Vision and Pattern Recognition · Computer Science 2021-04-02 Longguang Wang , Xiaoyu Dong , Yingqian Wang , Xinyi Ying , Zaiping Lin , Wei An , Yulan Guo

Image super-resolution (SR) aims to reconstruct high resolution images with both high perceptual quality and low distortion, but is fundamentally limited by the perception-distortion trade-off. GAN-based SR methods reduce distortion but…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Dan Wang , Haiyan Sun , Shan Du , Z. Jane Wang , Zhaochong An , Serge Belongie , Xinrui Cui

Image Phase Alignment Super-Sampling (ImPASS) is a computational imaging algorithm for converting a sequence of displaced low-resolution images into a single high-resolution image. The method consists of a unique combination of Phase…

Optics · Physics 2025-09-01 James N. Caron

Image super-resolution (SR) is one of the long-standing and active topics in image processing community. A large body of works for image super resolution formulate the problem with Bayesian modeling techniques and then obtain its…

Computer Vision and Pattern Recognition · Computer Science 2012-09-20 Haichao Zhang , David Wipf , Yanning Zhang

The diffraction of light imposes a fundamental limit on the resolution of light microscopes. This limit can be circumvented by creating and exploiting independent behaviors of the sample at length scales below the diffraction limit. In…

Biological Physics · Physics 2024-06-19 Mohamadreza Fazel , Michael J. Wester

Spatial transcriptomics provides an unprecedented perspective for deciphering tissue spatial heterogeneity. However, high-resolution spatial transcriptomic technology remains constrained by limited gene coverage, technical complexity, and…

Biomolecules · Quantitative Biology 2026-05-19 Xinlei Huang , Weihao Dai , Zijun Qin , Xin Yu , Di Wang , Yanran Liu , Lixin Cheng , Xubin Zheng