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Neural circuits exhibit structured connectivity, including an overrepresentation of reciprocal connections between neuron pairs. Despite important advances, a full understanding of how such partial symmetry in connectivity shapes neural…

Cortical activity in-vivo displays relaxational time scales much longer than the membrane time constant of the neurons or the deactivation time of ionotropic synaptic conductances. The mechanisms responsible for such slow dynamics are not…

Disordered Systems and Neural Networks · Physics 2025-08-07 Ferdinand Tixidre , Gianluigi Mongillo , Alessandro Torcini

Firing patterns in the central nervous system often exhibit strong temporal irregularity and heterogeneity in their time averaged response properties. Previous studies suggested that these properties are outcome of an intrinsic chaotic…

Disordered Systems and Neural Networks · Physics 2015-11-25 Jonathan Kadmon , Haim Sompolinsky

While most models of randomly connected networks assume nodes with simple dynamics, nodes in realistic highly connected networks, such as neurons in the brain, exhibit intrinsic dynamics over multiple timescales. We analyze how the…

Disordered Systems and Neural Networks · Physics 2019-09-11 Samuel P. Muscinelli , Wulfram Gerstner , Tilo Schwalger

Recurrent Neural Network models have elucidated the interplay between structure and dynamics in biological neural networks, particularly the emergence of irregular and rhythmic activities in cortex. However, most studies have focused on…

Neurons and Cognition · Quantitative Biology 2025-09-04 Nimrod Sherf , Xaq Pitkow , Krešimir Josić , Kevin E. Bassler

Functional connectivity is a fundamental property of neural networks that quantifies the segregation and integration of information between cortical areas. Due to mathematical complexity, a theory that could explain how the parameters of…

Neurons and Cognition · Quantitative Biology 2016-05-27 Diego Fasoli , Anna Cattani , Stefano Panzeri

For large fully connected neuron networks, we study the dynamics of homogenous assemblies of interacting neurons described by time elapsed models. Under general assumptions on the firing rate which include the ones made in previous works…

Analysis of PDEs · Mathematics 2018-08-29 Stéphane Mischler , Cristobal Quiñinao , Qilong Weng

Neural circuits exhibit complex activity patterns, both spontaneously and evoked by external stimuli. Information encoding and learning in neural circuits depend on how well time-varying stimuli can control spontaneous network activity. We…

Neurons and Cognition · Quantitative Biology 2023-01-11 Rainer Engelken , Alessandro Ingrosso , Ramin Khajeh , Sven Goedeke , L. F. Abbott

The co-occurrence of action potentials of pairs of neurons within short time intervals is known since long. Such synchronous events can appear time-locked to the behavior of an animal and also theoretical considerations argue for a…

Neurons and Cognition · Quantitative Biology 2022-05-17 Moritz Helias , Tom Tetzlaff , Markus Diesmann

The dynamical behaviour of a weakly diluted fully-inhibitory network of pulse-coupled spiking neurons is investigated. Upon increasing the coupling strength, a transition from regular to stochastic-like regime is observed. In the…

Disordered Systems and Neural Networks · Physics 2007-05-23 R. Zillmer , R. Livi , A. Politi , A. Torcini

We revisit the dynamics of a prototypical model of balanced activity in networks of spiking neutrons. A detailed investigation of the thermodynamic limit for fixed density of connections (massive coupling) shows that, when inhibition…

Adaptation and Self-Organizing Systems · Physics 2018-09-03 Ekkehard Ullner , Antonio Politi , Alessandro Torcini

A mechanism for self-organization of the degree of connectivity in model neural networks is studied. Network connectivity is regulated locally on the basis of an order parameter of the global dynamics which is estimated from an observable…

Statistical Mechanics · Physics 2009-11-07 Stefan Bornholdt , Torsten Roehl

Cortical neurons are characterized by irregular firing and a broad distribution of rates. The balanced state model explains these observations with a cancellation of mean excitatory and inhibitory currents, which makes fluctuations drive…

Neurons and Cognition · Quantitative Biology 2020-10-15 Alessandro Sanzeni , Mark H Histed , Nicolas Brunel

A given neural network in the brain is involved in many different tasks. This implies that, when considering a specific task, the network's connectivity contains a component which is related to the task and another component which can be…

Neurons and Cognition · Quantitative Biology 2021-03-17 Friedrich Schuessler , Alexis Dubreuil , Francesca Mastrogiuseppe , Srdjan Ostojic , Omri Barak

Electrical coupling between neurons is broadly present across brain areas and is typically assumed to synchronize network activity. However, intrinsic properties of the coupled cells can complicate this simple picture. Many cell types with…

Adaptation and Self-Organizing Systems · Physics 2018-01-19 Thomas Chartrand , Mark S. Goldman , Timothy J. Lewis

The mathematical theory of pattern formation in electrically coupled networks of excitable neurons forced by small noise is presented in this work. Using the Freidlin-Wentzell large deviation theory for randomly perturbed dynamical systems…

Pattern Formation and Solitons · Physics 2012-06-05 Georgi S. Medvedev , Svitlana Zhuravytska

We construct and analyze a rate-based neural network model in which self-interacting units represent clusters of neurons with strong local connectivity and random inter-unit connections reflect long-range interactions. When sufficiently…

Disordered Systems and Neural Networks · Physics 2015-06-22 Merav Stern , Haim Sompolinsky , L. F. Abbott

The cooperative behavior of neurons and neuronal areas associated with the synchronization behavior proves to be a fundamental neural mechanism. In addition, abnormal levels of synchronization have been related to unhealthy neural…

Biological Physics · Physics 2023-11-16 Bruno R. R. Boaretto

Synchronous firing of neurons is thought to play important functional roles such as feature binding and switching of cognitive states. Although synchronization has mainly been investigated using model neurons with simple connection topology…

Neurons and Cognition · Quantitative Biology 2024-11-26 Naoki Masuda , Kazuyuki Aihara

This paper introduces a class of stochastic models of interacting neurons with emergent dynamics similar to those seen in local cortical populations, and compares them to very simple reduced models driven by the same mean excitatory and…

Neurons and Cognition · Quantitative Biology 2017-11-07 Yao Li , Logan Chariker , Lai-Sang Young
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