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Oral Squamous Cell Carcinoma (OSCC) is a common type of cancer of the oral epithelium. Despite their high impact on mortality, sufficient screening methods for early diagnosis of OSCC often lack accuracy and thus OSCCs are mostly diagnosed…

Computer Vision and Pattern Recognition · Computer Science 2017-09-21 Marc Aubreville , Christian Knipfer , Nicolai Oetter , Christian Jaremenko , Erik Rodner , Joachim Denzler , Christopher Bohr , Helmut Neumann , Florian Stelzle , Andreas Maier

Squamous Cell Carcinoma (SCC) is the most common cancer type of the epithelium and is often detected at a late stage. Besides invasive diagnosis of SCC by means of biopsy and histo-pathologic assessment, Confocal Laser Endomicroscopy (CLE)…

Computer Vision and Pattern Recognition · Computer Science 2020-01-06 Marc Aubreville , Miguel Goncalves , Christian Knipfer , Nicolai Oetter , Helmut Neumann , Florian Stelzle , Christopher Bohr , Andreas Maier

Confocal laser endomicroscopy (CLE) is an advanced optical fluorescence technology undergoing assessment for applications in brain tumor surgery. Despite its promising potential, interpreting the unfamiliar gray tone images of fluorescent…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Mohammadhassan Izadyyazdanabadi , Evgenii Belykh , Michael Mooney , Nikolay Martirosyan , Jennifer Eschbacher , Peter Nakaji , Mark C. Preul , Yezhou Yang

Confocal laser endomicroscopy (CLE), although capable of obtaining images at cellular resolution during surgery of brain tumors in real time, creates as many non-diagnostic as diagnostic images. Non-useful images are often distorted due to…

Computer Vision and Pattern Recognition · Computer Science 2018-01-09 Mohammadhassan Izadyyazdanabadi , Evgenii Belykh , Nikolay Martirosyan , Jennifer Eschbacher , Peter Nakaji , Yezhou Yang , Mark C. Preul

Confocal laser endomicroscopy (CLE) is an advanced optical fluorescence imaging technology that has the potential to increase intraoperative precision, extend resection, and tailor surgery for malignant invasive brain tumors because of its…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Mohammadhassan Izadyyazdanabadi , Evgenii Belykh , Michael Mooney , Jennifer Eschbacher , Peter Nakaji , Yezhou Yang , Mark C. Preul

Confocal Laser Endomicroscopy (CLE), an optical imaging technique allowing non-invasive examination of the mucosa on a (sub)cellular level, has proven to be a valuable diagnostic tool in gastroenterology and shows promising results in…

Computer Vision and Pattern Recognition · Computer Science 2018-05-07 Maike P. Stoeve , Marc Aubreville , Nicolai Oetter , Christian Knipfer , Helmut Neumann , Florian Stelzle , Andreas Maier

The goal of the present study is to analyze an application of deep learning models in order to augment the diagnostic performance of oral squamous cell carcinoma (OSCC) with a longitudinal cohort study using the Histopathological Imaging…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Samiha Islam , Muhammad Zawad Mahmud , Shahran Rahman Alve , Md. Mejbah Ullah Chowdhury , Faija Islam Oishe

Oral Cavity Squamous Cell Carcinoma (OCSCC) is the most common type of head and neck cancer. Due to the subtle nature of its early stages, deep and hidden areas of development, and slow growth, OCSCC often goes undetected, leading to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Vishal Manikanden , Aniketh Bandlamudi , Daniel Haehn

Confocal Laser Endomicroscope (CLE) is a novel handheld fluorescence imaging device that has shown promise for rapid intraoperative diagnosis of brain tumor tissue. Currently CLE is capable of image display only and lacks an automatic…

Background and Aim: Over-fitting issue has been the reason behind deep learning technology not being successfully implemented in oral cancer images classification. The aims of this research were reducing overfitting for accurately producing…

Image and Video Processing · Electrical Eng. & Systems 2022-08-17 Prakrit Joshi , Omar Hisham Alsadoon , Abeer Alsadoon , Nada AlSallami , Tarik A. Rashid , P. W. C. Prasad , Sami Haddad

Oral squamous cell carcinoma (OSCC) represents a significant global health concern, with increasing incidence rates and challenges in early diagnosis and treatment planning. Early detection is crucial for improving patient outcomes and…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Samrat Kumar Dev Sharma

The surgical removal of head and neck tumors requires safe margins, which are usually confirmed intraoperatively by means of frozen sections. This method is, in itself, an oversampling procedure, which has a relatively low sensitivity…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Marc Aubreville , Zhaoya Pan , Matti Sievert , Jonas Ammeling , Jonathan Ganz , Nicolai Oetter , Florian Stelzle , Ann-Kathrin Frenken , Katharina Breininger , Miguel Goncalves

An automatic segmentation algorithm for delineation of the gross tumour volume and pathologic lymph nodes of head and neck cancers in PET/CT images is described. The proposed algorithm is based on a convolutional neural network using the…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Yngve Mardal Moe , Aurora Rosvoll Groendahl , Martine Mulstad , Oliver Tomic , Ulf Indahl , Einar Dale , Eirik Malinen , Cecilia Marie Futsaether

Convolutional neural networks (CNNs) have shown great promise in improving computer aided detection (CADe). From classifying tumors found via mammography as benign or malignant to automated detection of colorectal polyps in CT colonography,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Hunter Park , Connor Monahan

Breast cancer is one of the most prevalent cancers worldwide and pathologists are closely involved in establishing a diagnosis. Tools to assist in making a diagnosis are required to manage the increasing workload. In this context,…

Early detection of lung cancer is critical to improving survival outcomes. We present a deep learning framework for automated lung cancer screening from chest computed tomography (CT) images with integrated explainability. Using the…

Image and Video Processing · Electrical Eng. & Systems 2026-01-07 Nishan Rai , Sujan Khatri , Devendra Risal

Confocal laser endomicroscopy (CLE) is a novel imaging modality that provides in vivo histological cross-sections of examined tissue. Recently, attempts have been made to develop miniaturized in vivo imaging devices, specifically confocal…

Computer Vision and Pattern Recognition · Computer Science 2018-06-22 Saeed Izadi , Kathleen P. Moriarty , Ghassan Hamarneh

Background and Aim: Recently, deep learning using convolutional neural network has been used successfully to classify the images of breast cells accurately. However, the accuracy of manual classification of those histopathological images is…

Image and Video Processing · Electrical Eng. & Systems 2021-08-11 Ashu Thapa , Abeer Alsadoon , P. W. C. Prasad , Simi Bajaj , Omar Hisham Alsadoon , Tarik A. Rashid , Rasha S. Ali , Oday D. Jerew

Oral cancer incidence is rapidly increasing worldwide. The most important determinant factor in cancer survival is early diagnosis. To facilitate large scale screening, we propose a fully automated pipeline for oral cancer detection on…

Image and Video Processing · Electrical Eng. & Systems 2020-09-14 Jiahao Lu , Nataša Sladoje , Christina Runow Stark , Eva Darai Ramqvist , Jan-Michaél Hirsch , Joakim Lindblad

Lung and Colon cancer are one of the leading causes of mortality and morbidity in adults. Histopathological diagnosis is one of the key components to discern cancer type. The aim of the present research is to propose a computer aided…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Sanidhya Mangal , Aanchal Chaurasia , Ayush Khajanchi
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