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State-of-the-art electron microscopes such as scanning electron microscopes (SEM), scanning transmission electron microscopes (STEM) and transmission electron microscopes (TEM) have become increasingly sophisticated. However, the quality of…

Computational Physics · Physics 2023-03-31 I. Lobato , T. Friedrich , S. Van Aert

We demonstrate that a deep neural network can significantly improve optical microscopy, enhancing its spatial resolution over a large field-of-view and depth-of-field. After its training, the only input to this network is an image acquired…

Machine Learning · Computer Science 2017-11-21 Yair Rivenson , Zoltan Gorocs , Harun Gunaydin , Yibo Zhang , Hongda Wang , Aydogan Ozcan

In current biological and medical research, statistical shape modeling (SSM) provides an essential framework for the characterization of anatomy/morphology. Such analysis is often driven by the identification of a relatively small number of…

Computer Vision and Pattern Recognition · Computer Science 2021-11-16 Riddhish Bhalodia , Shireen Elhabian , Ladislav Kavan , Ross Whitaker

In the past few years, convolutional neural networks (CNNs) have achieved milestones in medical image analysis. Especially, the deep neural networks based on U-shaped architecture and skip-connections have been widely applied in a variety…

Image and Video Processing · Electrical Eng. & Systems 2021-05-13 Hu Cao , Yueyue Wang , Joy Chen , Dongsheng Jiang , Xiaopeng Zhang , Qi Tian , Manning Wang

Semantic segmentation of medical images with deep learning models is rapidly developed. In this study, we benchmarked state-of-the-art deep learning segmentation algorithms on our clinical stereotactic radiosurgery dataset, demonstrating…

Image and Video Processing · Electrical Eng. & Systems 2020-07-24 Siang-Ruei Wu , Hao-Yun Chang , Florence T Su , Heng-Chun Liao , Wanju Tseng , Chun-Chih Liao , Feipei Lai , Feng-Ming Hsu , Furen Xiao

We present three multi-scale similarity learning architectures, or DeepSim networks. These models learn pixel-level matching with a contrastive loss and are agnostic to the geometry of the considered scene. We establish a middle ground…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Mohamed Ali Chebbi , Ewelina Rupnik , Marc Pierrot-Deseilligny , Paul Lopes

In recent years, significant progress has been made in developing more accurate and efficient machine learning algorithms for segmentation of medical and natural images. In this review article, we highlight the imperative role of machine…

Image and Video Processing · Electrical Eng. & Systems 2019-11-07 Hyunseok Seo , Masoud Badiei Khuzani , Varun Vasudevan , Charles Huang , Hongyi Ren , Ruoxiu Xiao , Xiao Jia , Lei Xing

We propose a method of aligning a source image to a target image, where the transform is specified by a dense vector field. The two images are encoded as feature hierarchies by siamese convolutional nets. Then a hierarchy of aligner modules…

Computer Vision and Pattern Recognition · Computer Science 2019-04-05 Eric Mitchell , Stefan Keselj , Sergiy Popovych , Davit Buniatyan , H. Sebastian Seung

Deep learning with a convolutional neural network (CNN) has been proved to be very effective in feature extraction and representation of images. For image classification problems, this work aim at finding which classifier is more…

Machine Learning · Computer Science 2015-06-09 Lei Zhang , David Zhang

We propose a novel non-rigid image registration algorithm that is built upon fully convolutional networks (FCNs) to optimize and learn spatial transformations between pairs of images to be registered. Different from most existing deep…

Computer Vision and Pattern Recognition · Computer Science 2017-09-05 Hongming Li , Yong Fan

Convolutional neural networks (CNNs) have been the de facto standard in a diverse set of computer vision tasks for many years. Especially, deep neural networks based on seminal architectures such as U-shaped models with skip-connections or…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Reza Azad , Moein Heidari , Moein Shariatnia , Ehsan Khodapanah Aghdam , Sanaz Karimijafarbigloo , Ehsan Adeli , Dorit Merhof

Convolutional neural networks (CNNs) have been the consensus for medical image segmentation tasks. However, they suffer from the limitation in modeling long-range dependencies and spatial correlations due to the nature of convolution…

Computer Vision and Pattern Recognition · Computer Science 2023-01-10 Moein Heidari , Amirhossein Kazerouni , Milad Soltany , Reza Azad , Ehsan Khodapanah Aghdam , Julien Cohen-Adad , Dorit Merhof

In image segmentation, there is often more than one plausible solution for a given input. In medical imaging, for example, experts will often disagree about the exact location of object boundaries. Estimating this inherent uncertainty and…

Computer Vision and Pattern Recognition · Computer Science 2020-12-23 Miguel Monteiro , Loïc Le Folgoc , Daniel Coelho de Castro , Nick Pawlowski , Bernardo Marques , Konstantinos Kamnitsas , Mark van der Wilk , Ben Glocker

In the past, optimization-based registration models have used spatially-varying regularization to account for deformation variations in different image regions. However, deep learning-based registration models have mostly relied on…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Junyu Chen , Yihao Liu , Yufan He , Yong Du

Recent advances in deep learning-based medical image registration have shown that training deep neural networks~(DNNs) does not necessarily require medical images. Previous work showed that DNNs trained on randomly generated images with…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Junyu Chen , Shuwen Wei , Yihao Liu , Aaron Carass , Yong Du

Semantic segmentation is an established while rapidly evolving field in medical imaging. In this paper we focus on the segmentation of brain Magnetic Resonance Images (MRI) into cerebral structures using convolutional neural networks (CNN).…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Pierre-Antoine Ganaye , Michaël Sdika , Hugues Benoit-Cattin

The encoder-decoder framework is state-of-the-art for offline semantic image segmentation. Since the rise in autonomous systems, real-time computation is increasingly desirable. In this paper, we introduce fast segmentation convolutional…

Computer Vision and Pattern Recognition · Computer Science 2019-02-13 Rudra P K Poudel , Stephan Liwicki , Roberto Cipolla

It has been shown that traditional deep learning methods for electronic microscopy segmentation usually suffer from low transferability when samples and annotations are limited, while large-scale vision foundation models are more robust…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Yiran Wang , Li Xiao

One primary technical challenge in photoacoustic microscopy (PAM) is the necessary compromise between spatial resolution and imaging speed. In this study, we propose a novel application of deep learning principles to reconstruct…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Anthony DiSpirito , Daiwei Li , Tri Vu , Maomao Chen , Dong Zhang , Jianwen Luo , Roarke Horstmeyer , Junjie Yao

In the past few years, convolutional neural networks (CNNs), particularly U-Net, have been the prevailing technique in the medical image processing era. Specifically, the seminal U-Net, as well as its alternatives, have successfully managed…

Computer Vision and Pattern Recognition · Computer Science 2022-07-28 Reza Azad , Mohammad T. AL-Antary , Moein Heidari , Dorit Merhof