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Single-beam scanning electron microscopes (SEM) are widely used to acquire massive data sets for biomedical study, material analysis, and fabrication inspection. Datasets are typically acquired with uniform acquisition: applying the…

Image and Video Processing · Electrical Eng. & Systems 2021-01-11 Lu Mi , Hao Wang , Yaron Meirovitch , Richard Schalek , Srinivas C. Turaga , Jeff W. Lichtman , Aravinthan D. T. Samuel , Nir Shavit

The need for fast acquisition and automatic analysis of MRI data is growing in the age of big data. Although compressed sensing magnetic resonance imaging (CS-MRI) has been studied to accelerate MRI by reducing k-space measurements, in…

Computer Vision and Pattern Recognition · Computer Science 2018-05-08 Liyan Sun , Zhiwen Fan , Yue Huang , Xinghao Ding , John Paisley

We report resolution enhancement in scanning electron microscopy (SEM) images using a generative adversarial network. We demonstrate the veracity of this deep learning-based super-resolution technique by inferring unresolved features in…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Kevin de Haan , Zachary S. Ballard , Yair Rivenson , Yichen Wu , Aydogan Ozcan

The most established method of reconstructing neural circuits from animals involves slicing tissue very thin, then taking mosaics of electron microscope (EM) images. To trace neurons across different images and through different sections,…

Quantitative Methods · Quantitative Biology 2013-04-23 Louis K. Scheffer , Bill Karsh , Shiv Vitaladevun

Deep learning techniques have successfully been employed in numerous computer vision tasks including image segmentation. The techniques have also been applied to medical image segmentation, one of the most critical tasks in computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2020-06-30 Titinunt Kitrungrotsakul , Iwamoto Yutaro , Lanfen Lin , Ruofeng Tong , Jingsong Li , Yen-Wei Chen

Convolutional neural networks (CNNs) achieved the state-of-the-art performance in medical image segmentation due to their ability to extract highly complex feature representations. However, it is argued in recent studies that traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Zhendi Gong , Andrew P. French , Guoping Qiu , Xin Chen

In clinical practice, regions of interest in medical imaging often need to be identified through a process of precise image segmentation. The quality of this image segmentation step critically affects the subsequent clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2021-03-23 João B. S. Carvalho , João A. Santinha , Đorđe Miladinović , Joachim M. Buhmann

Deep learning-based image registration methods have shown state-of-the-art performance and rapid inference speeds. Despite these advances, many existing approaches fall short in capturing spatially varying information in non-local regions…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Xinxing Cheng , Tianyang Zhang , Wenqi Lu , Qingjie Meng , Alejandro F. Frangi , Jinming Duan

3D image segmentation plays an important role in biomedical image analysis. Many 2D and 3D deep learning models have achieved state-of-the-art segmentation performance on 3D biomedical image datasets. Yet, 2D and 3D models have their own…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Hao Zheng , Yizhe Zhang , Lin Yang , Peixian Liang , Zhuo Zhao , Chaoli Wang , Danny Z. Chen

Semantic image segmentation is one of fastest growing areas in computer vision with a variety of applications. In many areas, such as robotics and autonomous vehicles, semantic image segmentation is crucial, since it provides the necessary…

Computer Vision and Pattern Recognition · Computer Science 2020-09-29 Georgios Takos

Morphology of mitochondria plays critical roles in mediating their physiological functions. Accurate segmentation of mitochondria from 3D electron microscopy (EM) images is essential to quantitative characterization of their morphology at…

Computer Vision and Pattern Recognition · Computer Science 2022-06-16 Yunpeng Xiao , Youpeng Zhao , Ge Yang

Objective: Deformable brain MR image registration is challenging due to large inter-subject anatomical variation. For example, the highly complex cortical folding pattern makes it hard to accurately align corresponding cortical structures…

Computer Vision and Pattern Recognition · Computer Science 2019-02-07 Dongming Wei , Zhengwang Wu , Gang Li , Xiaohuan Cao , Dinggang Shen , Qian Wang

Recently, deep learning with Convolutional Neural Networks (CNNs) and Transformers has shown encouraging results in fully supervised medical image segmentation. However, it is still challenging for them to achieve good performance with…

Image and Video Processing · Electrical Eng. & Systems 2022-03-02 Xiangde Luo , Minhao Hu , Tao Song , Guotai Wang , Shaoting Zhang

One of the most common tasks in medical imaging is semantic segmentation. Achieving this segmentation automatically has been an active area of research, but the task has been proven very challenging due to the large variation of anatomy…

Computer Vision and Pattern Recognition · Computer Science 2018-04-10 Holger R. Roth , Chen Shen , Hirohisa Oda , Masahiro Oda , Yuichiro Hayashi , Kazunari Misawa , Kensaku Mori

Medical image segmentation, particularly in multi-domain scenarios, requires precise preservation of anatomical structures across diverse representations. While deep learning has advanced this field, existing models often struggle with…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Afshin Bozorgpour , Sina Ghorbani Kolahi , Reza Azad , Ilker Hacihaliloglu , Dorit Merhof

Image segmentation is a fundamental and challenging problem in computer vision with applications spanning multiple areas, such as medical imaging, remote sensing, and autonomous vehicles. Recently, convolutional neural networks (CNNs) have…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Ali Hatamizadeh

Image registration is a fundamental task for medical imaging. Resampling of the intensity values is required during registration and better spatial resolution with finer and sharper structures can improve the resampling performance and…

Image and Video Processing · Electrical Eng. & Systems 2022-01-03 Kaicong Sun , Sven Simon

Biomedical image segmentation plays a significant role in computer-aided diagnosis. However, existing CNN based methods rely heavily on massive manual annotations, which are very expensive and require huge human resources. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2023-01-13 Ruifei Zhang , Sishuo Liu , Yizhou Yu , Guanbin Li

Registration plays an important role in medical image analysis. Deep learning-based methods have been studied for medical image registration, which leverage convolutional neural networks (CNNs) for efficiently regressing a dense deformation…

Computer Vision and Pattern Recognition · Computer Science 2022-08-16 Xiaoru Gao , GuoYan Zheng

Atom segmentation and localization, noise reduction and deblurring of atomic-resolution scanning transmission electron microscopy (STEM) images with high precision and robustness is a challenging task. Although several conventional…

Materials Science · Physics 2021-02-23 Ruoqian Lin , Rui Zhang , Chunyang Wang , Xiao-Qing Yang , Huolin L. Xin