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Ki67 is an important biomarker for breast cancer. Classification of positive and negative Ki67 cells in histology slides is a common approach to determine cancer proliferation status. However, there is a lack of generalizable and accurate…

We propose a fully-automated method for accurate and robust detection and segmentation of potentially cancerous lesions found in the liver and in lymph nodes. The process is performed in three steps, including organ detection, lesion…

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

Breast cancer ranks as the most prevalent form of cancer diagnosed in women, and diagnosis faces several challenges, a change in the size, shape and appearance of breasts, dense breast tissue, lumps or thickening in the breast especially if…

Breast cancer is one of the most common cancers in women worldwide, and early detection can significantly reduce the mortality rate of breast cancer. It is crucial to take multi-scale information of tissue structure into account in the…

Presenting whole slide images (WSIs) as graph will enable a more efficient and accurate learning framework for cancer diagnosis. Due to the fact that a single WSI consists of billions of pixels and there is a lack of vast annotated datasets…

Nuclear pleomorphism, defined herein as the extent of abnormalities in the overall appearance of tumor nuclei, is one of the components of the three-tiered breast cancer grading. Given that nuclear pleomorphism reflects a continuous…

The optimal treatment strategy of newly diagnosed glioma is strongly influenced by tumour malignancy. Manual non-invasive grading based on MRI is not always accurate and biopsies to verify diagnosis negatively impact overall survival. In…

Accurate prediction of the likelihood of recurrence is important in the selection of postoperative treatment for patients with early-stage breast cancer. In this study, we investigated whether deep learning algorithms can predict patients'…

Correct treatment of urothelial carcinoma patients is dependent on accurate grading and staging of the cancer tumour. This is determined manually by a pathologist by examining the histological whole-slide images (WSI). The large size of…

Breast cancer is the second leading cause of cancer-related death after lung cancer in women. Early detection of breast cancer in X-ray mammography is believed to have effectively reduced the mortality rate. However, a relatively high false…

Cancer grading is an essential task in pathology. The recent developments of artificial neural networks in computational pathology have shown that these methods hold great potential for improving the accuracy and quality of cancer…

Digital pathology and microscopy image analysis are widely employed in the segmentation of digitally scanned IHC slides, primarily to identify cancer and pinpoint regions of interest (ROI) indicative of tumor presence. However, current ROI…

Breast cancer is the most common invasive cancer in women, and the second main cause of death. Breast cancer screening is an efficient method to detect indeterminate breast lesions early. The common approaches of screening for women are…

Deep learning models have achieved promising results in breast cancer classification, yet their 'black-box' nature raises interpretability concerns. This research addresses the crucial need to gain insights into the decision-making process…

Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin \& eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher…

Purpose: To develop a deep network architecture that would achieve fully automated radiologist-level segmentation of cancers at breast MRI. Materials and Methods: In this retrospective study, 38229 examinations (composed of 64063 individual…

Background: Breast cancer has the highest prevalence in women globally. The classification and diagnosis of breast cancer and its histopathological images have always been a hot spot of clinical concern. In Computer-Aided Diagnosis (CAD),…

We present a deep convolutional neural network for breast cancer screening exam classification, trained and evaluated on over 200,000 exams (over 1,000,000 images). Our network achieves an AUC of 0.895 in predicting whether there is a…

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…