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Over nearly two decades, Differential Dynamic Microscopy (DDM) has become a standard technique for extracting dynamic correlation functions from time-lapse microscopy data, with applications spanning colloidal suspensions, polymer…

Soft Condensed Matter · Physics 2025-11-11 Enrico Lattuada , Fabian Krautgasser , Maxime Lavaud , Fabio Giavazzi , Roberto Cerbino

This review summarizes recent progress in investigating polymer systems by using Differential dynamic microscopy (DDM), a rapidly emerging approach that transforms a commercial microscope by combining real-space information with the…

Soft Condensed Matter · Physics 2021-06-07 Roberto Cerbino , Fabio Giavazzi , Matthew E. Helgeson

Differential dynamic microscopy (DDM) is increasingly used in the fields of soft matter physics and biophysics to extract the dynamics of microscopic objects across a range of wavevectors using optical microscopy. Standard DDM is limited to…

Soft Condensed Matter · Physics 2021-02-24 Ruilin You , Ryan McGorty

Particle size is a key variable in understanding the behaviour of the particulate products that underpin much of our modern lives. Typically obtained from suspensions at rest, measuring the particle size under flowing conditions would…

Soft Condensed Matter · Physics 2021-07-22 James A Richards , Vincent A Martinez , Jochen Arlt

We have developed a lab work module where we teach undergraduate students how to quantify the dynamics of a suspension of microscopic particles, measuring and analyzing the motion of those particles at the individual level or as a group.…

Soft Condensed Matter · Physics 2016-02-23 David Germain , Mathieu Leocmach , Thomas Gibaud

Differential dynamic microscopy (DDM) is a form of video image analysis that combines the sensitivity of scattering and the direct visualization benefits of microscopy. DDM is broadly useful in determining dynamical properties including the…

Soft Condensed Matter · Physics 2022-04-12 Mengyang Gu , Yimin Luo , Yue He , Matthew E. Helgeson , Megan T. Valentine

Differential Dynamic Microscopy (DDM) is the combination of optical microscopy to statistical analysis to obtain information about the dynamical behaviour of a variety of samples spanning from soft matter physics to biology. In DDM, the…

Computer Vision and Pattern Recognition · Computer Science 2020-12-11 M. Norouzisadeh , G. Cerchiari , F. Croccolo

Differential dynamic microscopy (DDM) typically relies on movies containing hundreds or thousands of frames to accurately quantify motion in soft matter systems. Using movies much shorter in duration produces noisier and less accurate…

Soft Condensed Matter · Physics 2024-11-05 Gildardo Martinez , Justin Siu , Steven Dang , Dylan Gage , Emma Kao , Juan Carlos Avila , Ruilin You , Ryan McGorty

We discuss in two companion papers (arXiv:1802.03737 and the present manuscript) how Fourier-space measurements may be coupled to rheological tests in order to elucidate the relationship between mechanical properties and microscopic…

Soft Condensed Matter · Physics 2018-07-31 Stefano Aime , Luca Cipelletti

During In Vitro Fertilisation (IVF), combining time-lapse contrast microscopy with suitable image processing techniques could facilitate non-invasive classification of oocyte health, driving oocyte selection to maximise success rates. One…

Particle tracking microrheology (PT-$\mu$r) exploits the thermal motion of embedded particles to probe the local mechanical properties of soft materials. Despite its appealing conceptual simplicity, PT-$\mu$r requires calibration procedures…

Soft Condensed Matter · Physics 2018-01-03 Paolo Edera , Davide Bergamini , Véronique Trappe , Fabio Giavazzi , Roberto Cerbino

Differential dynamic microscopy (DDM) can be used to extract mean particle size from videos of suspensions. However, many suspensions have multimodal particle size distributions (PSDs), for which this is not a sufficient description. After…

Soft Condensed Matter · Physics 2023-10-17 Joe J Bradley , Vincent A Martinez , Jochen Arlt , John R Royer , Wilson C K Poon

Microscopy such as Scanning Tunneling Microscopy (STM), Atomic Force Microscopy (AFM) and Scanning Electron Microscopy (SEM) are essential tools in material imaging at micro- and nanoscale resolutions to extract physical knowledge and…

This paper presents an application of digital Fourier holography for selective imaging of scatterers with different sizes in turbid media such as biological tissues. A combination of Fourier holography and high-resolution digital recording,…

Optics · Physics 2007-05-23 Sergey A. Alexandrov , P. Meredith , T. J. McIntyre , A. V. Zvyagin

Analysis of microscope images is a tedious work which requires patience and time, usually done manually by the microscopist after data collection. Here we introduce an approach of automatic image analysis, which is based on locally applied…

Image and Video Processing · Electrical Eng. & Systems 2019-12-17 Benedykt R. Jany , Arkadiusz Janas , Franciszek Krok

An approach reported recently by Alexandrov et al. on optical scatter imaging, termed digital Fourier microscopy (DFM), represents an adaptation of digital Fourier holography to selective imaging of biological matter. Holographic mode of…

Optics · Physics 2007-05-23 K. Y. T. Seet , P. Blazkiewicz , P. Meredith , A. V. Zvyagin

Soft and biological materials are often composed of elementary constituents exhibiting an incessant roto-translational motion at the microscopic scale. Tracking this motion with a bright-field microscope becomes increasingly challenging…

Soft Condensed Matter · Physics 2021-04-30 Fabio Giavazzi , Antara Pal , Roberto Cerbino

Differential dynamic microscopy (DDM) is a digital video-microscopy technique for quantitative measurements of the microscale dynamics in soft condensed matter systems. Here, multi-tau pulsed illumination DDM (MTPI-DDM) is introduced as a…

Soft Condensed Matter · Physics 2026-05-19 Emmanuel Schaub , Martinus H. V. Werts

Dark-field X-ray Microscopy (DFXM) is a novel diffraction-based imaging technique that non-destructively maps the local deformation from crystalline defects in bulk materials. While studies have demonstrated that DFXM can spatially map 3D…

Dynamic Mode Decomposition (DMD) is a data-driven and model-free decomposition technique. It is suitable for revealing spatio-temporal features of both numerically and experimentally acquired data. Conceptually, DMD performs a…

Fluid Dynamics · Physics 2020-12-18 Tim Krake , Stefan Reinhardt , Marcel Hlawatsch , Bernhard Eberhardt , Daniel Weiskopf
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