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When working with large biological data sets, exploratory analysis is an important first step for understanding the latent structure and for generating hypotheses to be tested in subsequent analyses. However, when the number of variables is…

Methodology · Statistics 2017-02-03 Julia Fukuyama

Principal component analysis (PCA) is very popular to perform dimension reduction. The selection of the number of significant components is essential but often based on some practical heuristics depending on the application. Only few works…

Machine Learning · Statistics 2017-09-19 Clément Elvira , Pierre Chainais , Nicolas Dobigeon

We consider estimation of large approximate factor models in high-dimensional panels of stationary time series using Principal Component Analysis (PCA). We review the key results establishing the necessary and sufficient conditions for…

Econometrics · Economics 2026-02-13 Matteo Barigozzi

Dimensionality reduction is a critical preprocessing step for clustering high-dimensional data, yet comprehensive evaluation of its impact across diverse methods and data types remains limited. In this study, we systematically assess the…

Machine Learning · Computer Science 2026-05-13 Ousmane Assani-Amate , Mohammadreza Bakhtyari , Émilie Roy , Vladimir Makarenkov

Motivation: Although principal component analysis (PCA) is widely used for the dimensional reduction of biomedical data, interpretation of PCA results remains daunting. Most existing methods attempt to explain each principal component (PC)…

Quantitative Methods · Quantitative Biology 2015-08-24 H. Robert Frost , Zhigang Li , Jason H. Moore

We propose a modified, high-dimensional version of a recent dimension estimation procedure that determines the dimension via the introduction of augmented noise variables into the data. Our asymptotic results show that the proposal is…

Statistics Theory · Mathematics 2025-02-07 Una Radojicic , Joni Virta

Principal Component Analysis (PCA) is one of the most important methods to handle high dimensional data. However, most of the studies on PCA aim to minimize the loss after projection, which usually measures the Euclidean distance, though in…

Machine Learning · Computer Science 2019-03-19 Kai Liu , Qiuwei Li , Hua Wang , Gongguo Tang

Sequential or online dimensional reduction is of interests due to the explosion of streaming data based applications and the requirement of adaptive statistical modeling, in many emerging fields, such as the modeling of energy end-use…

Machine Learning · Statistics 2014-07-17 Zhaoyi Kang , Costas J. Spanos

In large-scale statistical modeling, reducing data size through subsampling is essential for balancing computational efficiency and statistical accuracy. We propose a new method, Principal Component Analysis guided Quantile Sampling…

Computation · Statistics 2026-01-13 Foo Hui-Mean , Yuan-chin Ivan Chang

In recent times, functional data analysis (FDA) has been successfully applied in the field of high dimensional data classification. In this paper, we present a novel classification framework using functional data and classwise Principal…

Machine Learning · Statistics 2021-06-29 Avishek Chatterjee , Satyaki Mazumder , Koel Das

Dimensionality reduction is a classical technique widely used for data analysis. One foundational instantiation is Principal Component Analysis (PCA), which minimizes the average reconstruction error. In this paper, we introduce the…

Discrete Mathematics · Computer Science 2020-06-17 Uthaipon Tantipongpipat , Samira Samadi , Mohit Singh , Jamie Morgenstern , Santosh Vempala

Current metagenomic analysis algorithms require significant computing resources, can report excessive false positives (type I errors), may miss organisms (type II errors / false negatives), or scale poorly on large datasets. This paper…

Databases · Computer Science 2015-01-23 Ashley Mae Conard , Stephanie Dodson , Jeremy Kepner , Darrell Ricke

Molecular simulations produce very high-dimensional data-sets with millions of data points. As analysis methods are often unable to cope with so many dimensions, it is common to use dimensionality reduction and clustering methods to reach a…

Machine Learning · Statistics 2017-11-03 Stefan Doerr , Igor Ariz-Extreme , Matthew J. Harvey , Gianni De Fabritiis

Principal component analysis (PCA) is by far the most widespread tool for unsupervised learning with high-dimensional data sets. Its application is popularly studied for the purpose of exploratory data analysis and online process…

Applications · Statistics 2019-02-12 Stefania Russo , Guangyu Li , Kris Villez

Data dimension reduction (DDR) is all about mapping data from high dimensions to low dimensions, various techniques of DDR are being used for image dimension reduction like Random Projections, Principal Component Analysis (PCA), the…

Computer Vision and Pattern Recognition · Computer Science 2022-11-18 Wisal Khan , Muhammad Turab , Waqas Ahmad , Syed Hasnat Ahmad , Kelash Kumar , Bin Luo

Over the past decades, more and more methods gain a giant development due to the development of technology. Evolutionary Algorithms are widely used as a heuristic method. However, the budget of computation increases exponentially when the…

Neural and Evolutionary Computing · Computer Science 2021-05-12 Yangjie Mei , Hao Wang

In tabular biomedical data analysis, tuning models to high accuracy is considered a prerequisite for discussing feature importance, as medical practitioners expect the validity of feature importance to correlate with performance. In this…

Machine Learning · Statistics 2025-10-20 Youngro Lee , Giacomo Baruzzo , Jeonghwan Kim , Jongmo Seo , Barbara Di Camillo

Many real-world machine learning applications are characterized by a huge number of features, leading to computational and memory issues, as well as the risk of overfitting. Ideally, only relevant and non-redundant features should be…

Machine Learning · Computer Science 2023-06-21 Paolo Bonetti , Alberto Maria Metelli , Marcello Restelli

Estimating intrinsic dimensionality of data is a classic problem in pattern recognition and statistics. Principal Component Analysis (PCA) is a powerful tool in discovering dimensionality of data sets with a linear structure; it, however,…

Computer Vision and Pattern Recognition · Computer Science 2010-02-11 Mingyu Fan , Nannan Gu , Hong Qiao , Bo Zhang

An important task for many if not all the scientific domains is efficient knowledge integration, testing and codification. It is often solved with model construction in a controllable computational environment. In spite of that, the…

Molecular Networks · Quantitative Biology 2018-11-06 Emilia M. Wysocka , Valery Dzutsati , Tirthankar Bandyopadhyay , Laura Condon , Sahil Garg
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