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Fluorescence microscopy is a key driver to promote discoveries of biomedical research. However, with the limitation of microscope hardware and characteristics of the observed samples, the fluorescence microscopy images are susceptible to…

Image and Video Processing · Electrical Eng. & Systems 2022-09-15 Xuanyu Tian , Qing Wu , Hongjiang Wei , Yuyao Zhang

The human brain is a complex network comprised of functionally and anatomically interconnected brain regions. A growing number of studies have suggested that empirical estimates of brain networks may be useful for discovery of biomarkers of…

Neurons and Cognition · Quantitative Biology 2022-11-15 Andrew Hannum , Mario A. Lopez , Saúl A. Blanco , Richard F. Betzel

Independent component analysis (ICA) of multi-subject functional magnetic resonance imaging (fMRI) data has proven useful in providing a fully multivariate summary that can be used for multiple purposes. ICA can identify patterns that can…

Neurons and Cognition · Quantitative Biology 2022-11-15 Fateme Ghayem , Hanlu Yang , Furkan Kantar , Seung-Jun Kim , Vince D. Calhoun , Tulay Adali

We propose a method for estimating more reproducible functional networks that are more strongly associated with dynamic task activity by using recurrent neural networks with long short term memory (LSTMs). The LSTM model is trained in an…

Quantitative Methods · Quantitative Biology 2021-05-07 Nicha C. Dvornek , Pamela Ventola , James S. Duncan

In this paper, we aim at automatically searching an efficient network architecture for dense image prediction. Particularly, we follow the encoder-decoder style and focus on designing a connectivity structure for the decoder. To achieve…

Computer Vision and Pattern Recognition · Computer Science 2019-08-06 Huikai Wu , Junge Zhang , Kaiqi Huang

Low dimensional nonlinear structure abounds in datasets across computer vision and machine learning. Kernelized matrix factorization techniques have recently been proposed to learn these nonlinear structures for denoising, classification,…

Machine Learning · Computer Science 2021-06-01 Jicong Fan , Chengrun Yang , Madeleine Udell

Sparse dictionary learning (DL) has emerged as a powerful approach to extract semantically meaningful concepts from the internals of large language models (LLMs) trained mainly in the text domain. In this work, we explore whether DL can…

Brain functional connectivity (FC) extracted from resting-state fMRI (RS-fMRI) has become a popular approach for disease diagnosis, where discriminating subjects with mild cognitive impairment (MCI) from normal controls (NC) is still one of…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Weizheng Yan , Han Zhang , Jing Sui , Dinggang Shen

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

In this paper, we propose a novel information theoretic framework for dictionary learning (DL) and sparse coding (SC) on a statistical manifold (the manifold of probability distributions). Unlike the traditional DL and SC framework, our new…

Computer Vision and Pattern Recognition · Computer Science 2018-05-08 Rudrasis Chakraborty , Monami Banerjee , Baba C. Vemuri

Functional magnetic resonance imaging (fMRI) is a non-invasive and in-vivo imaging technique essential for measuring brain activity. Functional connectivity is used to study associations between brain regions, either while study subjects…

Applications · Statistics 2024-03-26 Kun Meng , Ani Eloyan

Sparse representation models a signal as a linear combination of a small number of dictionary atoms. As a generative model, it requires the dictionary to be highly redundant in order to ensure both a stable high sparsity level and a low…

Computer Vision and Pattern Recognition · Computer Science 2015-06-23 Xiaoxia Sun , Nasser M. Nasrabadi , Trac D. Tran

Dynamic functional connectivity (dFC) using resting-state functional magnetic resonance imaging (rs-fMRI) is an advanced technique for capturing the dynamic changes of neural activities, and can be very useful in the studies of brain…

Image and Video Processing · Electrical Eng. & Systems 2025-01-29 Jing Zhang , Yanjun Lyu , Xiaowei Yu , Lu Zhang , Chao Cao , Tong Chen , Minheng Chen , Yan Zhuang , Tianming Liu , Dajiang Zhu

Regularization for denoising in magnetic resonance imaging (MRI) is typically achieved using convex regularization functions. Recently, deep learning techniques have been shown to provide superior denoising performance. However, this comes…

Signal Processing · Electrical Eng. & Systems 2025-08-21 Akash Prabakar , Abhishek Shreekant Bhandiwad , Abijith Jagannath Kamath , Chandra Sekhar Seelamantula

Large language models (LLMs) have recently demonstrated state-of-the-art performance across various natural language processing (NLP) tasks, achieving near-human levels in multiple language understanding challenges and aligning closely with…

Signal Processing · Electrical Eng. & Systems 2025-07-08 Zhenyi Wang , Li Zou , Shengyun Wei , Kai Li , Feifan Liao , Haibo Mi , Rongxuan Lai

Decoding non-invasive brain recordings is pivotal for advancing our understanding of human cognition but faces challenges due to individual differences and complex neural signal representations. Traditional methods often require customized…

Neural and Evolutionary Computing · Computer Science 2024-10-15 Guobin Shen , Dongcheng Zhao , Xiang He , Linghao Feng , Yiting Dong , Jihang Wang , Qian Zhang , Yi Zeng

Brain decoding, aiming to identify the brain states using neural activity, is important for cognitive neuroscience and neural engineering. However, existing machine learning methods for fMRI-based brain decoding either suffer from low…

Neurons and Cognition · Quantitative Biology 2022-10-13 Ziyuan Ye , Youzhi Qu , Zhichao Liang , Mo Wang , Quanying Liu

The functional and structural representation of the brain as a complex network is marked by the fact that the comparison of noisy and intrinsically correlated high-dimensional structures between experimental conditions or groups shuns…

Neurons and Cognition · Quantitative Biology 2013-10-25 Tommaso Furlanello , Marco Cristoforetti , Cesare Furlanello , Giuseppe Jurman

The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…

Machine Learning · Computer Science 2025-05-27 Andrew Zamai , Nathanael Fijalkow , Boris Mansencal , Laurent Simon , Eloi Navet , Pierrick Coupe

Deep learning had already demonstrated its power in medical images, including denoising, classification, segmentation, etc. All these applications are proposed to automatically analyze medical images beforehand, which brings more…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Shao-Cheng Wen , Yu-Jen Chen , Zihao Liu , Wujie Wen , Xiaowei Xu , Yiyu Shi , Tsung-Yi Ho , Qianjun Jia , Meiping Huang , Jian Zhuang
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