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In the analysis of multivariate spatial and univariate spatio-temporal data, it is commonly recognized that asymmetric dependence may exist, which can be addressed using an asymmetric (matrix or space-time, respectively) covariance function…

Methodology · Statistics 2026-01-29 Drew Yarger

The study of infectious disease epidemiology for multi-type disease pathogens requires modelling techniques that account for the complex interactions existing between strains across geography and time. In this paper, we propose a novel…

Methodology · Statistics 2026-05-06 Matthew Adeoye , Simon E. F. Spencer , Xavier Didelot

Elevated levels of PM10 are known to cause severe respiratory and cardiovascular diseases, and, in extreme cases, cancer and mortality. Despite various reduction policies implemented across different sectors, PM10 concentrations in South…

Applications · Statistics 2025-03-21 Soyun Jeon , Jungsoon Choi

Epidemic data often possess certain characteristics, such as the presence of many zeros, the spatial nature of the disease spread mechanism or environmental noise. This paper addresses these issues via suitable Bayesian modelling. In doing…

Applications · Statistics 2014-03-10 C. Malesios , N. Demiris , K. Kalogeropoulos , I. Ntzoufras

Most cancers in humans are large, measuring centimeters in diameter, composed of many billions of cells. An equivalent mass of normal cells would be highly heterogeneous as a result of the mutations that occur during each cell division.…

Populations and Evolution · Quantitative Biology 2016-02-17 Bartlomiej Waclaw , Ivana Bozic , Meredith E. Pittman , Ralph H. Hruban , Bert Vogelstein , Martin A. Nowak

Illness-death models are a class of stochastic models inside the multi-state framework. In those models, individuals are allowed to move over time between different states related to illness and death. They are of special interest when…

Applications · Statistics 2022-10-14 Fran Llopis-Cardona , Carmen Armero , Gabriel Sanfélix-Gimeno

The problem of broad practical interest in spatiotemporal data analysis, i.e., discovering interpretable dynamic patterns from spatiotemporal data, is studied in this paper. Towards this end, we develop a time-varying reduced-rank vector…

Machine Learning · Computer Science 2022-11-29 Xinyu Chen , Chengyuan Zhang , Xiaoxu Chen , Nicolas Saunier , Lijun Sun

Melanoma represents a critical health risk due to its aggressive progression and high mortality, underscoring the need for early, interpretable diagnostic tools. While deep learning has advanced in skin lesion classification, most existing…

Computer Vision and Pattern Recognition · Computer Science 2025-07-28 Ciro Listone , Aniello Murano

Estimation of heterogeneous treatment effects is an active area of research. Most of the existing methods, however, focus on estimating the conditional average treatment effects of a single, binary treatment given a set of pre-treatment…

Methodology · Statistics 2025-05-30 Max Goplerud , Kosuke Imai , Nicole E. Pashley

The widespread application of Electronic Health Records (EHR) data in the medical field has led to early successes in disease risk prediction using deep learning methods. These methods typically require extensive data for training due to…

Machine Learning · Computer Science 2024-11-28 Shibo Li , Hengliang Cheng , Weihua Li

Temporal data, obtained in the setting where it is only possible to observe one time point per experiment, is widely used in different research fields, yet remains insufficiently addressed from the statistical point of view. Such data often…

Methodology · Statistics 2025-03-10 Polina Arsenteva , Mohamed Amine Benadjaoud , Hervé Cardot

The spatial composition and cellular heterogeneity of the tumor microenvironment plays a critical role in cancer development and progression. High-definition pathology imaging of tumor biopsies provide a high-resolution view of the spatial…

Applications · Statistics 2024-06-25 Nathaniel Osher , Jian Kang , Arvind Rao , Veerabhadran Baladandayuthapani

Air pollution remains a major environmental risk factor that is often associated with adverse health outcomes. However, quantifying and evaluating its effects on human health is challenging due to the complex nature of exposure data. Recent…

Methodology · Statistics 2025-06-02 Soumyakanti Pan , Sudipto Banerjee

Sequential Monte Carlo methods are a powerful framework for approximating the posterior distribution of a state variable in a sequential manner. They provide an attractive way of analyzing dynamic systems in real-time, taking into account…

Populations and Evolution · Quantitative Biology 2024-08-29 Dhorasso Temfack , Jason Wyse

Social scientists now routinely draw on high-frequency, high-granularity ''microlevel'' data to estimate the causal effects of subnational interventions. To date, most researchers aggregate these data into panels, often tied to large-scale…

Methodology · Statistics 2025-11-07 Mitsuru Mukaigawara , Kosuke Imai , Jason Lyall , Georgia Papadogeorgou

Factor analysis has been extensively used to reveal the dependence structures among multivariate variables, offering valuable insight in various fields. However, it cannot incorporate the spatial heterogeneity that is typically present in…

Methodology · Statistics 2024-11-14 Yanxiu Jin , Tomoya Wakayama , Renhe Jiang , Shonosuke Sugasawa

Medical vision-language pre-training methods mainly leverage the correspondence between paired medical images and radiological reports. Although multi-view spatial images and temporal sequences of image-report pairs are available in…

Artificial Intelligence · Computer Science 2024-05-31 Jinxia Yang , Bing Su , Wayne Xin Zhao , Ji-Rong Wen

Ambulance demand estimation at fine time and location scales is critical for fleet management and dynamic deployment. We are motivated by the problem of estimating the spatial distribution of ambulance demand in Toronto, Canada, as it…

This paper addresses the task of modeling severity losses using segmentation when the data distribution does not fall into the usual regression frameworks. This situation is not uncommon in lines of business such as third-party liability…

Applications · Statistics 2021-11-29 Martin Bladt

Multivariate spatial disease mapping has become a pivotal part of everyday practice in social epidemiology. Despite the existence of several specifications for the relation between different outcomes, there is still a need for a new…

Applications · Statistics 2024-10-30 P. Escobar-Hernández , A. López-Quílez , F. Palmí-Perales , M. Marco
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