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An important part of breast cancer staging is the assessment of the sentinel axillary node for early signs of tumor spreading. However, this assessment by pathologists is not always easy and retrospective surveys often requalify the status…

Quantitative Methods · Quantitative Biology 2024-04-30 Eric Bonnet

Computational protein design has a wide variety of applications. Despite its remarkable success, designing a protein for a given structure and function is still a challenging task. On the other hand, the number of solved protein structures…

Quantitative Methods · Quantitative Biology 2018-04-26 Jingxue Wang , Huali Cao , John Z. H. Zhang , Yifei Qi

We compare a set of convolutional neural network (CNN) architectures for the task of segmenting and detecting human sperm cells in an image taken from a semen sample. In contrast to previous work, samples are not stained or washed to allow…

Computer Vision and Pattern Recognition · Computer Science 2017-04-04 Malte Stær Nissen , Oswin Krause , Kristian Almstrup , Søren Kjærulff , Torben Trindkær Nielsen , Mads Nielsen

TASED-Net is a 3D fully-convolutional network architecture for video saliency detection. It consists of two building blocks: first, the encoder network extracts low-resolution spatiotemporal features from an input clip of several…

Computer Vision and Pattern Recognition · Computer Science 2019-08-19 Kyle Min , Jason J. Corso

In video super-resolution, the spatio-temporal coherence between, and among the frames must be exploited appropriately for accurate prediction of the high resolution frames. Although 2D convolutional neural networks (CNNs) are powerful in…

Computer Vision and Pattern Recognition · Computer Science 2019-06-21 Soo Ye Kim , Jeongyeon Lim , Taeyoung Na , Munchurl Kim

Deep learning with convolutional neural networks (ConvNets) have dramatically improved learning capabilities of computer vision applications just through considering raw data without any prior feature extraction. Nowadays, there is rising…

Signal Processing · Electrical Eng. & Systems 2019-07-15 Apdullah Yayık , Yakup Kutlu , Gökhan Altan

Spatial-wise dynamic convolution has become a promising approach to improving the inference efficiency of deep networks. By allocating more computation to the most informative pixels, such an adaptive inference paradigm reduces the spatial…

Computer Vision and Pattern Recognition · Computer Science 2022-10-13 Yizeng Han , Zhihang Yuan , Yifan Pu , Chenhao Xue , Shiji Song , Guangyu Sun , Gao Huang

Proteins perform critical processes in all living systems: converting solar energy into chemical energy, replicating DNA, as the basis of highly performant materials, sensing and much more. While an incredible range of functionality has…

Biomolecules · Quantitative Biology 2021-09-29 Leonardo V. Castorina , Rokas Petrenas , Kartic Subr , Christopher W. Wood

Protein structure prediction is pivotal for understanding the structure-function relationship of proteins, advancing biological research, and facilitating pharmaceutical development and experimental design. While deep learning methods and…

Machine Learning · Computer Science 2024-12-30 Kaihui Cheng , Ce Liu , Qingkun Su , Jun Wang , Liwei Zhang , Yining Tang , Yao Yao , Siyu Zhu , Yuan Qi

Deep convolutional neural networks (DCNNs) have shown remarkable performance in image classification tasks in recent years. Generally, deep neural network architectures are stacks consisting of a large number of convolutional layers, and…

Computer Vision and Pattern Recognition · Computer Science 2017-09-07 Dongyoon Han , Jiwhan Kim , Junmo Kim

Large-scale supervised pretraining is rapidly reshaping 3D medical image segmentation. However, existing efforts focus primarily on increasing dataset size and overlook the question of whether the backbone network is an effective…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Saikat Roy , Yannick Kirchhoff , Constantin Ulrich , Maximillian Rokuss , Tassilo Wald , Fabian Isensee , Klaus Maier-Hein

Proteins are sequences of amino acids that serve as the basic building blocks of living organisms. Despite rapidly growing databases documenting structural and functional information for various protein sequences, our understanding of…

Biomolecules · Quantitative Biology 2025-01-06 Weihang Dai

Convolutional neural networks (CNN) are increasingly used in many areas of computer vision. They are particularly attractive because of their ability to "absorb" great quantities of labeled data through millions of parameters. However, as…

Machine Learning · Computer Science 2015-06-16 Wenlin Chen , James T. Wilson , Stephen Tyree , Kilian Q. Weinberger , Yixin Chen

In this work we investigate the effect of the convolutional network depth on its accuracy in the large-scale image recognition setting. Our main contribution is a thorough evaluation of networks of increasing depth using an architecture…

Computer Vision and Pattern Recognition · Computer Science 2015-04-13 Karen Simonyan , Andrew Zisserman

Deep convolutional neural networks have proven their effectiveness, and have been acknowledged as the most dominant method for image classification. However, a severe drawback of deep convolutional neural networks is poor explainability.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Bin Wang , Wenbin Pei , Bing Xue , Mengjie Zhang

The rapid advancements in machine learning, graphics processing technologies and the availability of medical imaging data have led to a rapid increase in the use of deep learning models in the medical domain. This was exacerbated by the…

Quantitative Methods · Quantitative Biology 2020-10-14 Satya P. Singh , Lipo Wang , Sukrit Gupta , Haveesh Goli , Parasuraman Padmanabhan , Balázs Gulyás

We have developed a deep learning algorithm for chemical shift prediction for atoms in molecular crystals that utilizes an atom-centered Gaussian density model for the 3D data representation of a molecule. We define multiple channels that…

Protein function is inherently linked to its localization within the cell, and fluorescent microscopy data is an indispensable resource for learning representations of proteins. Despite major developments in molecular representation…

Quantitative Methods · Quantitative Biology 2022-05-25 Anastasia Razdaibiedina , Alexander Brechalov

Convolutional neural networks (CNNs) have shown great capability of solving various artificial intelligence tasks. However, the increasing model size has raised challenges in employing them in resource-limited applications. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2018-09-06 Hongyang Gao , Zhengyang Wang , Shuiwang Ji

We present a convolutional network that is equivariant to rigid body motions. The model uses scalar-, vector-, and tensor fields over 3D Euclidean space to represent data, and equivariant convolutions to map between such representations.…

Machine Learning · Computer Science 2018-10-30 Maurice Weiler , Mario Geiger , Max Welling , Wouter Boomsma , Taco Cohen