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The formation of bacterial biofilms on solid surfaces within a fluid starts when bacteria attach to the substrate. Understanding environmental factors affecting the attachment and the early stages of the biofilm development as well as the…

Applied Physics · Physics 2019-10-30 Sung-Ha Hong , Jean-Baptiste Gorce , Horst Punzmann , Nicolas Francois , Michael Shats , Hua Xia

Biofilms are bacterial aggregates that grow on moist surfaces. Thin homogeneous biofilms naturally formed on the walls of conducts may serve as biosensors, providing information on the status of microsystems (MEMS) without disrupting them.…

Soft Condensed Matter · Physics 2024-01-17 Ana Carpio , Baldvin Einarsson , David R. Espeso

Biofilms are ubiquitous macro-colonies of bacteria that develop at various interfaces (solid-liquid, solid-gas or liquid-gas). The formation of biofilms starts with the attachment of individual bacteria to an interface, where they…

Biological Physics · Physics 2016-11-03 Sarah Trinschek , Karin John , Uwe Thiele

Biofilm growth changes many physical properties of porous media such as porosity, permeability and mass transport parameters. The growth depends on various environmental conditions, and in particular, on flow rates. Modeling the evolution…

Biofilms inhabit a range of environments, such as dental plaques or soil micropores, often characterized by intricate, non-even surfaces. However, the impact of surface irregularities on the population dynamics of biofilms remains elusive…

Populations and Evolution · Quantitative Biology 2023-08-31 Witold Postek , Klaudia Staskiewicz , Elin Lilja , Bartlomiej Waclaw

Collective behavior of bacterial colonies plays critical roles in adaptability, survivability, biofilm expansion and infection. We employ an individual-based model of an interstitial biofilm to study emergent pattern formation based on the…

Adaptation and Self-Organizing Systems · Physics 2017-02-01 Cameron Zachreson , Christian Wolff , Cynthia B. Whitchurch , Milos Toth

The spatial organization of bacteria in dense biofilms is key to their collective behaviour, and understanding it will be important for medical and technological applications. Here we study the morphology of a compact biofilm that undergoes…

Biological Physics · Physics 2019-03-05 Xin Wang , Howard A. Stone , Ramin Golestanian

Biofilms are antibiotic-resistant bacterial aggregates that grow on moist surfaces and can trigger hospital-acquired infections. They provide a classical example in biology where the dynamics of cellular communities may be observed and…

Biological Physics · Physics 2015-02-24 D. R. Espeso , A. Carpio , B. Einarsson

We propose a general parametrizable model to capture the dynamic interaction among bacteria in the formation of micro-colonies. micro-colonies represent the first social step towards the formation of structured multicellular communities…

Populations and Evolution · Quantitative Biology 2014-10-30 Luca Canzian , Kun Zhao , Gerard C. L. Wong , Mihaela van der Schaar

Formation of bacterial colonies as biofilm on the surface/interface of various objects has the potential to impact not only human health and disease but also energy and environmental considerations. Biofilms can be regarded as soft…

Fluid Dynamics · Physics 2015-09-15 Pallab Barai , Aloke Kumar , Partha P. Mukherjee

Bacterial biofilms play a significant role in various fields that impact our daily lives, from detrimental public health hazards to beneficial applications in bioremediation, biodegradation, and wastewater treatment. However,…

Bacterial cellulose biofilms are complex networks of strong interwoven nanofibers that control transport and protect bacterial colonies in the film. Design of diverse applications of bacterial cellulose films also relies on understanding…

Soft Condensed Matter · Physics 2022-06-09 Firoozeh Babayekhorasani , Maryam Hosseini , Patrick T. Spicer

Bacterial growth and division generally occur by the process known as binary fission, in which the cells grow polarly until they divide into two daughter cells. Although this process is affected by factors that introduce stochastic…

Soft Condensed Matter · Physics 2022-10-05 Andrés Delgado-Campos , Alejandro Cuetos

The goal of this work is to develop a numerical simulation that accurately captures the biomechanical response of bacterial biofilms and their associated extracellular matrix (ECM). In this, the second of a two-part effort, the primary…

A bacterial biofilm is an aggregate of micro-organisms growing fixed onto a solid surface, rather than floating freely in a liquid. Biofilms play a major role in various practical situations such as surgical infections and water treatment.…

Analysis of PDEs · Mathematics 2023-06-06 Tommi Brander , Daniel Lesnic , Kai Cao

Biofilms are microbial collectives that occupy a diverse array of surfaces. The function and evolution of biofilms are strongly influenced by the spatial arrangement of different strains and species within them, but how spatiotemporal…

Populations and Evolution · Quantitative Biology 2018-07-04 Ricardo Martinez-Garcia , Carey D. Nadell , Raimo Hartmann , Knut Drescher , Juan A. Bonachela

Biofilms are communities of microorganisms that grow on virtually all surfaces with sufficient nutrients including aquatic and industrial water systems and medical devices. Biofilms are complex, structured communities where the interplay of…

Biological Physics · Physics 2023-07-13 Mark Owkes , Kai Coblentza , Austen Erikssona , Takumi Kammerzella , Philip S. Stewart

Biofilms, bacteria cells surrounded by a self-produced polymeric matrix, are common on medical devices and lead to many hospital infections. The biofilm lifecycle includes disassembly and dispersion, where bacteria clusters detach from the…

Quantitative Methods · Quantitative Biology 2026-05-18 Yuehui Xu , Jasmine A. F. Kreig , Zhuoran Wang , Elizabeth J. Stewart , Rayanne A. Luke , Sarah D. Olson

We propose a model of antibiotic diffusion through a bacterial biofilm when diffusion and/or absorption barriers develop in the biofilm. The idea of this model is: We deduce details of the diffusion process in a medium in which direct…

Biological Physics · Physics 2020-09-23 Tadeusz Kosztołowicz , Ralf Metzler

Growing tissue and bacterial colonies are active matter systems where cell divisions and cellular motion generate active stress. Although they operate in the non-equilibrium regime, these biological systems can form large-scale ordered…

Biological Physics · Physics 2019-05-28 Yusuf Ilker Yaman , Esin Demir , Roman Vetter , Askin Kocabas