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In recent past, experiments and simulations have suggested that apart from the solvent friction, friction arising from the protein itself plays an important role in protein folding by affecting the intra-chain loop formation dynamics. This…

Soft Condensed Matter · Physics 2014-06-25 Nairhita Samanta , Jayanta Ghosh , Rajarshi Chakrabarti

We introduce a new dynamic light scattering method, termed photon correlation imaging, which enables us to resolve the dynamics of soft matter in space and time. We demonstrate photon correlation imaging by investigating the slow dynamics…

Soft Condensed Matter · Physics 2009-03-02 Agnes Duri , David A. Sessoms , Veronique Trappe , Luca Cipelletti

We report molecular dynamics simulation results for two-component fluid mixtures of Gaussian-core particles, focusing on how tracer diffusivities and static pair correlations depend on temperature, particle concentration, and composition.…

Soft Condensed Matter · Physics 2009-11-04 Mark J. Pond , William P. Krekelberg , Vincent K. Shen , Jeffrey R. Errington , Thomas M. Truskett

The dynamics of a tracer particle in a glassy matrix of obstacles displays slow complex transport as the free volume approaches a critical value and the void space falls apart. We investigate the emerging subdiffusive motion of the test…

Statistical Mechanics · Physics 2011-01-20 Thomas Franosch , Markus Spanner , Teresa Bauer , Gerd E. Schröder-Turk , Felix Höfling

Cluster concepts have been extremely useful in elucidating many problems in physics. Percolation theory provides a generic framework to study the behavior of the cluster distribution. In most cases the theory predicts a geometrical…

Statistical Mechanics · Physics 2016-09-15 Antonio Coniglio , Annalisa Fierro

Numerous studies have investigated the differences and similarities between protein structures determined by solution NMR spectroscopy and those determined by x-ray crystallography. A fundamental question is whether any observed differences…

Biomolecules · Quantitative Biology 2022-10-10 Alex T. Grigas , Zhuoyi Liu , Lynne Regan , Corey S. O'Hern

Fluctuations in the abundance of molecules in the living cell may affect its growth and well being. For regulatory molecules (e.g., signaling proteins or transcription factors), fluctuations in their expression can affect the levels of…

Molecular Networks · Quantitative Biology 2009-11-13 Erel Levine , Terence Hwa

By means of computer simulations and solution of the equations of the Mode Coupling Theory (MCT), we investigate the role of the intramolecular barriers on several dynamic aspects of non-entangled polymers. The investigated dynamic range…

Soft Condensed Matter · Physics 2015-05-18 Marco Bernabei , Angel J. Moreno , Emanuela Zaccarelli , Francesco Sciortino , Juan Colmenero

The eye lens is the most characteristic example of mammalian tissues exhibiting complex colloidal behaviour. In this paper we briefly describe how dynamics in colloidal suspensions can help addressing selected aspects of lens cataract which…

Soft Condensed Matter · Physics 2015-05-13 Spyros N. Yannopoulos , Vassiliki Petta

Growing experimental evidence indicates that topological defects could serve as organizing centers in the morphogenesis of tissues. Here, we provide a quantitative explanation for this phenomenon, rooted in the buckling theory of deformable…

Soft Condensed Matter · Physics 2022-04-21 Ludwig A. Hoffmann , Livio Nicola Carenza , Julia Eckert , Luca Giomi

Matrix stiffness expressions are derived for the particle movements in an assembly of rigid granules having compliant contacts. The derivations include stiffness terms that arise from the particle shapes at their contacts. These geometric…

Soft Condensed Matter · Physics 2019-01-23 Matthew R. Kuhn , Ching S. Chang

We report on ultrafast electron diffraction on high quality single crystal silicon. The ultrafast dynamics of the Bragg peaks exhibits a giant photo-induced response which can only be explained in the framework of dynamical diffraction…

Despite the enormous theoretical and application interests, a fundamental understanding of the glassy dynamics remains elusive. The static properties of glassy and ordinary liquids are similar, but their dynamics are dramatically different.…

Soft Condensed Matter · Physics 2023-11-21 Puneet Pareek , Monoj Adhikari , Chandan Dasgupta , Saroj Kumar Nandi

Computational docking methods can provide structural models of protein-protein complexes, but protein backbone flexibility upon association often thwarts accurate predictions. In recent blind challenges, medium or high accuracy models were…

Biomolecules · Quantitative Biology 2020-12-29 Ameya Harmalkar , Jeffrey J. Gray

AxFe2-ySe2 (A=K, Rb, Cs) superconductors may show a complex mixture of structural phases even in a single crystal form. A full sphere of the diffraction intensity has been collected, with the help of synchrotron radiation, for Cs0.8Fe1.6Se2…

We propose an explanation for the quadratic dependence on the momentum $Q$, of the broadening of the acoustic excitation peak recently found in the study of the dynamic structure factor of many real and simulated glasses. We ascribe the…

Disordered Systems and Neural Networks · Physics 2009-10-31 M. Montagna , G. Ruocco , G. Viliani , R. Di Leonardo , R. Dusi , G. Monaco , M. Sampoli , T. Scopigno

Emission from Active Galactic Nuclei is known to vary strongly over time over a wide energy band, but the origin of the variability and especially of the inter-band correlations is still not well established. Here we present the results of…

Astrophysics · Physics 2009-11-13 P. Arévalo , P. Uttley , S. Kaspi , E. Breedt , P. Lira , I. M. McHardy

Understanding how proteins structurally interact is crucial to modern biology, with applications in drug discovery and protein design. Recent machine learning methods have formulated protein-small molecule docking as a generative problem…

In living cells, proteins involved in specialized biochemical functions are often spatially organized within biomolecular condensates. Increasing evidence suggests that some of these condensates, including DNA repair condensates, emerge…

Soft Condensed Matter · Physics 2026-05-15 Léa Beaulès , Judith Miné-Hattab , Pierre Illien , Vincent Dahirel

We study poly-crystalline spherical drops of an aqueous suspension of highly charged colloidal spheres exposed to a colloid-free aqueous environment. Crystal contours were obtained from standard optical imaging. The crystal spheres first…