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The state-of-the-art cardiovascular disease diagnosis techniques use machine-learning algorithms based on feature extraction and classification. In this work, in contrast to a conventional single Electrocardiogram (ECG) lead, two leads are…

Signal Processing · Electrical Eng. & Systems 2023-05-26 Cheng Guo , Sajid Ahmed , Mohamed-Slim Alouini

Rare diseases affect hundreds of millions worldwide, yet diagnosis often spans years. Convectional pipelines decouple noisy evidence extraction from downstream inferential diagnosis, and general/medical large language models (LLMs) face…

Background: Biomedical data are usually collections of longitudinal data assessed at certain points in time. Clinical observations assess the presences and severity of symptoms, which are the basis for description and modeling of disease…

Databases · Computer Science 2023-07-26 Richard Fechner , Jens Dörpinghaus , Robert Rockenfeller , Jennifer Faber

We propose a framework for building patient-specific treatment recommendation models, building on the large recent literature on learning patient-level causal models and inspired by the target trial paradigm of Hernan and Robins. We focus…

Machine Learning · Statistics 2025-07-17 Rom Gutman , Shimon Sheiba , Omer Noy Klein , Naama Dekel Bird , Amit Gruber , Doron Aronson , Oren Caspi , Uri Shalit

Clinical decision-making requires reasoning over incomplete, imprecise, and linguistically expressed patient narratives. While large language models (LLMs) excel at extracting latent information from natural language, they lack the…

Artificial Intelligence · Computer Science 2026-05-26 Xiaoyang Fan , Yufan Cai , Zhe Hou , Jin Song Dong

A logic programming paradigm which expresses solutions to problems as stable models has recently been promoted as a declarative approach to solving various combinatorial and search problems, including planning problems. In this paradigm,…

Artificial Intelligence · Computer Science 2007-05-23 Maurice Bruynooghe

Although large language models (LLMs) have demonstrated impressive reasoning capabilities across general domains, their effectiveness in real-world clinical practice remains limited. This is likely due to their insufficient exposure to…

Modeling latent clinical constructs from unconstrained clinical interactions is a unique challenge in affective computing. We present ADAPTS (Agentic Decomposition for Automated Protocol-agnostic Tracking of Symptoms), a framework for…

Artificial Intelligence · Computer Science 2026-05-07 Alexandria K. Vail , Marcelo Cicconet , Katie Aafjes-van Doorn , Ryan Maroney , Marc Aafjes

Decision-making related to health is complex. Machine learning (ML) and patient generated data can identify patterns and insights at the individual level, where human cognition falls short, but not all ML-generated information is of equal…

Applications · Statistics 2021-01-15 Elliot G Mitchell , Esteban G Tabak , Matthew E Levine , Lena Mamykina , David J Albers

Novel information retrieval methods to identify citations relevant to a clinical topic can overcome the knowledge gap existing between the primary literature (MEDLINE) and online clinical knowledge resources such as UpToDate. Searching the…

Computation and Language · Computer Science 2016-09-07 Kalpana Raja , Andrew J Sauer , Ravi P Garg , Melanie R Klerer , Siddhartha R Jonnalagadda

Model Predictive Control (MPC) is widely used to operate safety-critical infrastructure by predicting future trajectories and optimizing control actions. However, nonlinear dynamics, hard safety constraints, and numerical optimization often…

Artificial Intelligence · Computer Science 2026-05-12 Ramesh Arvind Naagarajan , Zühal Wagner , Stefan Streif

Atrial fibrillation (AF) increases the risk of stroke by a factor of four to five and is the most common abnormal heart rhythm. The progression of AF with age, from short self-terminating episodes to persistence, varies between individuals…

Tissues and Organs · Quantitative Biology 2016-10-12 Kishan A. Manani , Kim Christensen , Nicholas S. Peters

Hypertension (HPT) refers to a condition where the pressure exerted on the walls of arteries by blood pumped from the heart to the body reaches levels that can lead to various ailments. Annually, a significant number of lives are lost…

Signal Processing · Electrical Eng. & Systems 2023-11-08 Yunus Emre Erdoğan , Ali Narin , Walid Hariri

Since high data volume and complex data formats delivered in modern high-end production environments go beyond the scope of classical process control systems, more advanced tools involving machine learning are required to reliably recognize…

Machine Learning · Computer Science 2022-04-04 Stefan Schrunner , Michael Scheiber , Anna Jenul , Anja Zernig , Andre Kästner , Roman Kern

This paper addresses the challenge of enhancing artificial intelligence reasoning capabilities, focusing on logicality within the Abstraction and Reasoning Corpus (ARC). Humans solve such visual reasoning tasks based on their observations…

Artificial Intelligence · Computer Science 2024-11-28 Mintaek Lim , Seokki Lee , Liyew Woletemaryam Abitew , Sundong Kim

Low-dose chest computed tomography (LDCT) captures pulmonary and cardiac structures in a single scan, enabling joint assessment of lung and cardiovascular health. Existing approaches typically model these domains independently and do not…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Yifei Zhang , Jiashuo Zhang , Mojtaba Safari , Xiaofeng Yang , Liang Zhao

We study the framework of abductive logic programming extended with integrity constraints. For this framework, we introduce a new measure of the simplicity of an explanation based on its degree of \emph{arbitrariness}: the more arbitrary…

Logic in Computer Science · Computer Science 2020-02-19 Luciano Caroprese , Irina Trubitsyna , Miroslaw Truszczynski , Ester Zumpano

To mitigate hallucinations in large language models (LLMs), we propose a framework that focuses on errors induced by prompts. Our method extends a chain-style knowledge distillation approach by incorporating a programmable module that…

Computation and Language · Computer Science 2026-01-08 Jinbo Hao , Kai Yang , Qingzhen Su , Yifan Li , Chao Jiang

We propose a clinical decision support system (CDSS) for mental health diagnosis that combines the strengths of large language models (LLMs) and constraint logic programming (CLP). Having a CDSS is important because of the high complexity…

Artificial Intelligence · Computer Science 2025-02-24 Brian Hyeongseok Kim , Chao Wang

Heart failure (HF) poses a significant public health challenge, with a rising global mortality rate. Early detection and prevention of HF could significantly reduce its impact. We introduce a novel methodology for predicting HF risk using…

Quantitative Methods · Quantitative Biology 2025-06-19 Chen Chen , Lei Li , Marcel Beetz , Abhirup Banerjee , Ramneek Gupta , Vicente Grau