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The DNA microarray technology has modernized the approach of biology research in such a way that scientists can now measure the expression levels of thousands of genes simultaneously in a single experiment. Gene expression profiles, which…

Computational Engineering, Finance, and Science · Computer Science 2011-09-07 G. Victo Sudha George , V. Cyril Raj

In the field of functional genomics, the analysis of gene expression profiles through Machine and Deep Learning is increasingly providing meaningful insight into a number of diseases. The paper proposes a novel algorithm to perform Feature…

Genomics · Quantitative Biology 2023-03-31 Carlo Adornetto , Gianluigi Greco

Many machine learning models have been proposed to classify phenotypes from gene expression data. In addition to their good performance, these models can potentially provide some understanding of phenotypes by extracting explanations for…

Genomics · Quantitative Biology 2024-02-05 Myriam Bontonou , Anaïs Haget , Maria Boulougouri , Benjamin Audit , Pierre Borgnat , Jean-Michel Arbona

Reading emotions precisely from segments of neural activity is crucial for the development of emotional brain-computer interfaces. Among all neural decoding algorithms, deep learning (DL) holds the potential to become the most promising…

Human-Computer Interaction · Computer Science 2023-03-09 Xinming Wu , Ji Dai

Electroencephalogram (EEG) decoding aims to identify the perceptual, semantic, and cognitive content of neural processing based on non-invasively measured brain activity. Traditional EEG decoding methods have achieved moderate success when…

Signal Processing · Electrical Eng. & Systems 2022-03-09 Xun Chen , Chang Li , Aiping Liu , Martin J. McKeown , Ruobing Qian , Z. Jane Wang

Machine learning (ML) approaches have been used to develop highly accurate and efficient applications in many fields including bio-medical science. However, even with advanced ML techniques, cancer classification using gene expression data…

Genomics · Quantitative Biology 2023-05-10 Mahmood Khalsan , Mu Mu , Eman Salih Al-Shamery , Lee Machado , Suraj Ajit , Michael Opoku Agyeman

Deep Learning (DL) aims at learning the \emph{meaningful representations}. A meaningful representation refers to the one that gives rise to significant performance improvement of associated Machine Learning (ML) tasks by replacing the raw…

Neural and Evolutionary Computing · Computer Science 2018-02-27 Yanan Sun , Gary G. Yen , Zhang Yi

Currently, Deep Convolutional Neural Networks (DCNNs) are used to solve all kinds of problems in the field of machine learning and artificial intelligence due to their learning and adaptation capabilities. However, most successful DCNN…

Neural and Evolutionary Computing · Computer Science 2020-12-01 Francisco Erivaldo Fernandes Junior , Gary G. Yen

The estimation of covariance matrices of gene expressions has many applications in cancer systems biology. Many gene expression studies, however, are hampered by low sample size and it has therefore become popular to increase sample size by…

Gene selection plays a pivotal role in oncology research for improving outcome prediction accuracy and facilitating cost-effective genomic profiling for cancer patients. This paper introduces two gene selection strategies for deep…

Genomics · Quantitative Biology 2024-03-05 Akhila Krishna , Ravi Kant Gupta , Pranav Jeevan , Amit Sethi

Micro expression recognition (MER) is a very challenging area of research due to its intrinsic nature and fine-grained changes. In the literature, the problem of MER has been solved through handcrafted/descriptor-based techniques. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-12 Monu Verma , Santosh Kumar Vipparthi , Girdhari Singh

One important issue commonly encountered in the analysis of microarray data is to decide which and how many genes should be selected for further studies. For discriminant microarray data analyses based on statistical models, such as the…

Quantitative Methods · Quantitative Biology 2009-11-09 Wentian Li , Fengzhu Sun , Ivo Grosse

Objective: Machine learning techniques have been used extensively for 12-lead electrocardiogram (ECG) analysis. For physiological time series, deep learning (DL) superiority to feature engineering (FE) approaches based on domain knowledge…

Machine Learning · Computer Science 2022-07-19 Eran Zvuloni , Jesse Read , Antônio H. Ribeiro , Antonio Luiz P. Ribeiro , Joachim A. Behar

There exist many high-dimensional data in real-world applications such as biology, computer vision, and social networks. Feature selection approaches are devised to confront with high-dimensional data challenges with the aim of efficient…

Machine Learning · Computer Science 2021-06-22 Mohsen Ghassemi Parsa , Hadi Zare , Mehdi Ghatee

The lack of well-structured metadata annotations complicates there-usability and interpretation of the growing amount of publicly available RNA expression data. The machine learning-based prediction of metadata(data augmentation) can…

Machine Learning · Computer Science 2019-09-27 Jelena Fiosina , Maksims Fiosins , Stefan Bonn

Deep facial expression recognition faces two challenges that both stem from the large number of trainable parameters: long training times and a lack of interpretability. We propose a novel method based on evolutionary algorithms, that deals…

Neural and Evolutionary Computing · Computer Science 2020-10-14 Emmanuel Dufourq , Bruce A. Bassett

The performance of a deep neural network is heavily dependent on its architecture and various neural architecture search strategies have been developed for automated network architecture design. Recently, evolutionary neural architecture…

Neural and Evolutionary Computing · Computer Science 2020-03-27 Haoyu Zhang , Yaochu Jin , Ran Cheng , Kuangrong Hao

Deep Learning (DL) is a two-step classification model that consists feature learning, generating feature representations using unsupervised ways and the supervised learning stage at the last step of model using at least two hidden layers on…

Machine Learning · Computer Science 2021-01-26 Gokhan Altan , Yakup Kutlu

The Extreme Learning Machine (ELM) is a growing statistical technique widely applied to regression problems. In essence, ELMs are single-layer neural networks where the hidden layer weights are randomly sampled from a specific distribution,…

Machine Learning · Statistics 2025-07-31 Daniela De Canditiis , Fabiano Veglianti

Deep learning has been widely used for protein engineering. However, it is limited by the lack of sufficient experimental data to train an accurate model for predicting the functional fitness of high-order mutants. Here, we develop SESNet,…

Quantitative Methods · Quantitative Biology 2023-04-10 Mingchen Li , Liqi Kang , Yi Xiong , Yu Guang Wang , Guisheng Fan , Pan Tan , Liang Hong