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Medical image segmentation plays a crucial role in computer-aided diagnosis. However, existing methods heavily rely on fully supervised training, which requires a large amount of labeled data with time-consuming pixel-wise annotations.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Yunqi Gu , Tao Zhou , Yizhe Zhang , Yi Zhou , Kelei He , Chen Gong , Huazhu Fu

Quantifying the number of molecules from fluorescence microscopy measurements is an important topic in cell biology and medical research. In this work, we present a consecutive algorithm for super-resolution (STED) scanning microscopy that…

Applications · Statistics 2023-10-03 Katharina Proksch , Frank Werner , Jan Keller-Findeisen , Haisen Ta , Axel Munk

Semiconductor manufacturing generates vast amounts of image data, crucial for defect identification and yield optimization, yet often exceeds manual inspection capabilities. Traditional clustering techniques struggle with high-dimensional,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Janhavi Giri , Attila Lengyel , Don Kent , Edward Kibardin

Advancements in fast electron detectors have enabled the statistically significant sampling of crystal structures on the nanometre scale by means of Scanning Electron Nanobeam Diffraction (SEND). Characterisation of structural similarity…

Materials Science · Physics 2022-07-28 Andy Bridger , William I. F. David , Thomas J. Wood , Mohsen Danaie , Keith T. Butler

Tremendous variation in the scale of people/head size is a critical problem for crowd counting. To improve the scale invariance of feature representation, recent works extensively employ Convolutional Neural Networks with multi-column…

Computer Vision and Pattern Recognition · Computer Science 2019-09-18 Zhi-Qi Cheng , Jun-Xiu Li , Qi Dai , Xiao Wu , Jun-Yan He , Alexander Hauptmann

It has been shown that genome spatial structures largely affect both genome activity and DNA function. Knowing this, many researchers are currently attempting to accurately model genome structures. Despite these increased efforts there…

Genomics · Quantitative Biology 2015-07-24 Jackson Nowotny , Avery Wells , Lingfei Xu , Renzhi Cao , Tuan Trieu , Chenfeng He , Jianlin Cheng

Nowadays, hyperspectral image classification widely copes with spatial information to improve accuracy. One of the most popular way to integrate such information is to extract hierarchical features from a multiscale segmentation. In the…

Computer Vision and Pattern Recognition · Computer Science 2016-06-17 Yanwei Cui , Laetitia Chapel , Sébastien Lefèvre

We consider the problem of distinguishing two vectors (visualized as images or barcodes) and learning if they are related to one another. For this, we develop a geometric quantum machine learning (GQML) approach with embedded symmetries…

Quantum Physics · Physics 2024-09-04 Chukwudubem Umeano , Stefano Scali , Oleksandr Kyriienko

Multidimensional scaling visualizes dissimilarities among objects and reduces data dimensionality. While many methods address symmetric proximity data, asymmetric and especially three-way proximity data (capturing relationships across…

Methodology · Statistics 2025-11-21 Aleix Alcacer , Rafael Benitez , Vicente J. Bolos , Irene Epifanio

Spectral clustering requires the time-consuming decomposition of the Laplacian matrix of the similarity graph, thus limiting its applicability to large datasets. To improve the efficiency of spectral clustering, a top-down approach was…

Machine Learning · Computer Science 2024-12-19 Zhichang Xu , Zhiguo Long , Hua Meng

Traditional pairwise sequence alignment is based on matching individual samples from two sequences, under time monotonicity constraints. However, in many application settings matching subsequences (segments) instead of individual samples…

Databases · Computer Science 2016-09-28 Shahriar Shariat , Vladimir Pavlovic

Graphs have become increasingly popular in modeling structures and interactions in a wide variety of problems during the last decade. Graph-based clustering and semi-supervised classification techniques have shown impressive performance.…

Machine Learning · Computer Science 2020-09-01 Zhao Kang , Chong Peng , Qiang Cheng , Xinwang Liu , Xi Peng , Zenglin Xu , Ling Tian

Time series anomaly detection (TSAD) plays a vital role in various domains such as healthcare, networks, and industry. Considering labels are crucial for detection but difficult to obtain, we turn to TSAD with inexact supervision: only…

Machine Learning · Computer Science 2024-01-23 Chen Liu , Shibo He , Haoyu Liu , Shizhong Li

One iteration of standard $k$-means (i.e., Lloyd's algorithm) or standard EM for Gaussian mixture models (GMMs) scales linearly with the number of clusters $C$, data points $N$, and data dimensionality $D$. In this study, we explore whether…

Machine Learning · Statistics 2018-04-18 Dennis Forster , Jörg Lücke

The development of single-cell and spatial transcriptomics has revolutionized our capacity to investigate cellular properties, functions, and interactions in both cellular and spatial contexts. However, the analysis of single-cell and…

Genomics · Quantitative Biology 2024-12-09 Shuang Ge , Shuqing Sun , Huan Xu , Qiang Cheng , Zhixiang Ren

Detecting anomalies in large complex systems is a critical and challenging task. The difficulties arise from several aspects. First, collecting ground truth labels or prior knowledge for anomalies is hard in real-world systems, which often…

Machine Learning · Computer Science 2021-06-01 Huiling Qin , Xianyuan Zhan , Yu Zheng

Geometric graph neural networks (GNNs) excel at capturing molecular geometry, yet their locality-biased message passing hampers the modeling of long-range interactions. Current solutions have fundamental limitations: extending cutoff radii…

Machine Learning · Computer Science 2025-09-29 Haodong Pan , Yusong Wang , Nanning Zheng , Caijui Jiang

Scientific Machine Learning (SciML) faces unique challenges for extreme-resolution data, with mitigations that often fail to scale or degrade the accuracy of trained models. While some specialized methods have achieved remarkable results in…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-13 Corey Adams , Peter Harrington , Akshay Subramaniam , Mohammad Shoaib Abbas , Jaideep Pathak , Mike Pritchard , Sanjay Choudhry

Analyses of targeted genomic sequencing data from next-generation-sequencing (NGS) technologies typically involves mapping reads to a reference sequence or clustering reads. For a number of species a reference genome is not available so the…

Genomics · Quantitative Biology 2016-02-16 Raunaq Malhotra , Daniel Elleder , Le Bao , David R Hunter , Raj Acharya , Mary Poss

Cardiac motion over a cardiac cycle is crucial for quantifying regional function and is strongly affected by cardiovascular diseases. Since temporally dense mesh sequences are difficult to obtain in practice, we focus on leveraging the more…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Xuan Yang , Xiaohan Yuan , Hao Li , Lingyu Chen , Yanan Liu , Lei Li
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