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Transport of ions and small molecules across the cell membrane against electrochemical gradients is catalyzed by integral membrane proteins that use a source of free energy to drive the energetically uphill flux of the transported…

Biomolecules · Quantitative Biology 2022-03-25 Oliver Beckstein , Fiona Naughton

We present a simple one-dimensional trapping model prompted by the problem of ion current across biological membranes. The trap is modeled mimicking the ionic channel membrane behaviour. Such voltage-sensitive channels are open or closed…

Statistical Mechanics · Physics 2009-10-31 Alejandro D. Sanchez , Jorge A. Revelli , Horacio S. Wio

In this paper, we have used Recurrent Neural Networks to capture and model human motion data and generate motions by prediction of the next immediate data point at each time-step. Our RNN is armed with recently proposed Gated Recurrent…

Neural and Evolutionary Computing · Computer Science 2015-01-05 Mohammad Pezeshki

Confinement is an ubiquitous phenomenon when matter couples to gauge fields, which manifests itself in a linear string potential between two static charges. Although gauge fields can be integrated out in one dimension, they can mediate…

We have observed an unusual dc current spontaneously generated in the conducting channel of a short-gated GaAs transistor. The magnitude and direction of this current critically depend upon the voltage applied to the gate. We propose that…

Mesoscale and Nanoscale Physics · Physics 2009-11-10 D. W. Horsell , A. K. Savchenko , Y. M. Galperin , V. I. Kozub , V. M. Vinokur , D. A. Ritchie

Many ion channels spontaneously switch between different levels of activity. Although this behaviour known as modal gating has been observed for a long time it is currently not well understood. Despite the fact that appropriately…

Quantitative Methods · Quantitative Biology 2018-08-14 Ivo Siekmann , Mark Fackrell , Edmund J. Crampin , Peter Taylor

We are interested in dynamics of quantum many-body systems under continuous observation, and its physical realizations involving cold atoms in lattices. In the present work we focus on continuous measurement of atomic currents in lattice…

Quantum Physics · Physics 2017-05-23 C. Laflamme , D. Yang , P. Zoller

We have observed thermal gating, i.e. electrostatic gating induced by hot electrons. The effect occurs in a device consisting of two capacitively coupled quantum dots. The double dot system is coupled to a hot electron reservoir on one side…

Electronic current densities can reach extreme values in highly conducting nanostructures where constrictions limit current. For bias voltages on the 1 volt scale, the highly non-equilibrium situation can influence the electronic density…

Mesoscale and Nanoscale Physics · Physics 2019-07-17 Susanne Leitherer , Nick Papior , Mads Brandbyge

We examine theoretically porous membranes in aqueous mixtures. We show that large membrane pores can be reversibly gated from `off' (co-solvent-rich, poor conductor of ions and other solutes) to 'on' (water-rich, good conductor) states by…

Soft Condensed Matter · Physics 2016-06-01 Sela Samin , Yoav Tsori

In this paper, we develop an explicit model to predict the DC electrical behavior in ultra-thin surrounding gate junctionless nanowire FET. The proposed model takes into account 2D electrical and geometrical confinements of carrier charge…

Applied Physics · Physics 2019-06-26 Danial Shafizade , Majid Shalchian , Farzan Jazaeri

We investigate the generation of squeezing and entanglement for the motional degrees of freedom of ions in linear traps, confined by time-varying and oscillating potentials, comprised of an DC and an AC component. We show that high degrees…

Quantum Physics · Physics 2010-10-27 Alessio Serafini , Alex Retzker , Martin B. Plenio

Gravity currents are a ubiquitous density driven flow occurring in both the natural environment and in industry. They include: seafloor turbidity currents, primary vectors of sediment, nutrient and pollutant transport; cold fronts; and…

Fluid Dynamics · Physics 2025-02-28 Edward W. G. Skevington , Robert M. Dorrell

Voltage-gated Kv channels play fundamental roles in many biological processes, such as the generation of the action potential. The gating mechanism of Kv channels is characterized experimentally by single-channel recordings and ensemble…

Biological Physics · Physics 2022-05-09 Zilong Song , Robert Eisenberg , Shixin Xu , Huaxiong Huang

Conservation of current and conservation of charge are nearly the same thing: when enough is known about charge movement, conservation of current can be derived from conservation of charge, in ideal dielectrics, for example. Conservation of…

Other Quantitative Biology · Quantitative Biology 2016-10-20 Bob Eisenberg

We numerically investigate the dynamic heterogeneity and its length scale found in the coarse-grained ionic liquid model systems. In our ionic liquid model systems, cations are modeled as dimers with positive charge, while anions are…

Soft Condensed Matter · Physics 2016-03-10 Soree Kim , Sang-Won Park , YounJoon Jung

One of the most fundamental questions we can ask about a given gauge theory is its phase diagram. In the standard model, we observe three fundamentally different types of behavior: QCD is in a confined phase at zero temperature, while the…

High Energy Physics - Theory · Physics 2015-06-12 Michael C. Ogilvie

The electron-positive fermion gas in three dimensions and $T=0$ is modeled as two independent fermion gases interacting via the coulomb interaction. The main advantage of the simple model is that all existing results from the electron gas…

Superconductivity · Physics 2024-11-27 Carl A. Kukkonen

Kinetic equations for the stationary state distribution function of ions moving through narrow pores are solved for a number of one-dimensional models of single ion transport. Ions move through pores of length $L$, under the action of a…

Soft Condensed Matter · Physics 2009-11-10 Jaroslaw Piasecki , Rosalind J. Allen , Jean-Pierre Hansen

The opening or closing mechanism of a voltage-gated ion channel is triggered by the potential difference crossing the cell membrane in the nervous system. Based on this picture, we model the ion channel as a nanoscale two-terminal ionic…

Biological Physics · Physics 2024-11-21 Yu-Juan Sun , Wei-Min Zhang