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In this paper, we introduce the semantic knowledge of medical images from their diagnostic reports to provide an inspirational network training and an interpretable prediction mechanism with our proposed novel multimodal neural network,…

Computer Vision and Pattern Recognition · Computer Science 2017-08-11 Zizhao Zhang , Pingjun Chen , Manish Sapkota , Lin Yang

Interpretable deep learning models have received widespread attention in the field of image recognition. Due to the unique multi-instance learning of medical images and the difficulty in identifying decision-making regions, many…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Yitao Peng , Lianghua He , Die Hu , Yihang Liu , Longzhen Yang , Shaohua Shang

Automated breast cancer detection via computer vision techniques is challenging due to the complex nature of breast tissue, the subtle appearance of cancerous lesions, and variations in breast density. Mainstream techniques primarily focus…

Quantitative Methods · Quantitative Biology 2025-12-11 Noor Ul Huda Shah , Tanveer Hussain , Amr Ahmed , Yonghuai Liu , Usman Ali , Ardhendu Behera

In this paper, an innovative multi-modal deep learning model is proposed to deeply integrate heterogeneous information from medical images and clinical reports. First, for medical images, convolutional neural networks were used to extract…

Machine Learning · Computer Science 2024-05-29 Ziyan Yao , Fei Lin , Sheng Chai , Weijie He , Lu Dai , Xinghui Fei

Large language models (LLMs) have recently demonstrated their potential in clinical applications, providing valuable medical knowledge and advice. For example, a large dialog LLM like ChatGPT has successfully passed part of the US medical…

Computer Vision and Pattern Recognition · Computer Science 2023-02-15 Sheng Wang , Zihao Zhao , Xi Ouyang , Qian Wang , Dinggang Shen

The ambiguity of the decision-making process has been pointed out as the main obstacle to applying the deep learning-based method in a practical way in spite of its outstanding performance. Interpretability could guarantee the confidence of…

Computer Vision and Pattern Recognition · Computer Science 2019-06-11 Hyebin Lee , Seong Tae Kim , Yong Man Ro

Automated interpretation of medical images demands robust modeling of complex visual-semantic relationships while addressing annotation scarcity, label imbalance, and clinical plausibility constraints. We introduce MIRNet (Medical Image…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Shufeng Kong , Zijie Wang , Nuan Cui , Hao Tang , Yihan Meng , Yuanyuan Wei , Feifan Chen , Yingheng Wang , Zhuo Cai , Yaonan Wang , Yulong Zhang , Yuzheng Li , Zibin Zheng , Caihua Liu , Hao Liang

Deep neural networks (DNN) have achieved unprecedented performance in computer-vision tasks almost ubiquitously in business, technology, and science. While substantial efforts are made to engineer highly accurate architectures and provide…

Image and Video Processing · Electrical Eng. & Systems 2022-09-08 Sumedha Singla

Computer-assisted diagnostic and prognostic systems of the future should be capable of simultaneously processing multimodal data. Multimodal deep learning (MDL), which involves the integration of multiple sources of data, such as images and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Zhaoyi Sun , Mingquan Lin , Qingqing Zhu , Qianqian Xie , Fei Wang , Zhiyong Lu , Yifan Peng

Recent works on Multimodal 3D Computer-aided diagnosis have demonstrated that obtaining a competitive automatic diagnosis model when a 3D convolution neural network (CNN) brings more parameters and medical images are scarce remains…

Computer Vision and Pattern Recognition · Computer Science 2022-01-25 Yin Dai , Yifan Gao , Fayu Liu , Jun Fu

Accurate segmentation of lesions plays a critical role in medical image analysis and diagnosis. Traditional segmentation approaches that rely solely on visual features often struggle with the inherent uncertainty in lesion distribution and…

Image and Video Processing · Electrical Eng. & Systems 2025-04-03 Dandan Shan , Zihan Li , Yunxiang Li , Qingde Li , Jie Tian , Qingqi Hong

Medical image analysis is essential to clinical diagnosis and treatment, which is increasingly supported by multi-modal large language models (MLLMs). However, previous research has primarily focused on 2D medical images, leaving 3D images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Fan Bai , Yuxin Du , Tiejun Huang , Max Q. -H. Meng , Bo Zhao

Medical imaging is an essential tool in many areas of medical applications, used for both diagnosis and treatment. However, reading medical images and making diagnosis or treatment recommendations require specially trained medical…

Computer Vision and Pattern Recognition · Computer Science 2019-03-13 Wentao Zhu

Recent applications of deep convolutional neural networks in medical imaging raise concerns about their interpretability. While most explainable deep learning applications use post hoc methods (such as GradCAM) to generate feature…

Computer Vision and Pattern Recognition · Computer Science 2023-04-17 Yuanyuan Wei , Roger Tam , Xiaoying Tang

Medical image classification is a critical problem for healthcare, with the potential to alleviate the workload of doctors and facilitate diagnoses of patients. However, two challenges arise when deploying deep learning models to real-world…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 An Yan , Yu Wang , Yiwu Zhong , Zexue He , Petros Karypis , Zihan Wang , Chengyu Dong , Amilcare Gentili , Chun-Nan Hsu , Jingbo Shang , Julian McAuley

In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Boyu Zhang , Aleksandar Vakanski , Min Xian

When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

In this paper, we propose a new deep network that learns multi-level deep representations for image emotion classification (MldrNet). Image emotion can be recognized through image semantics, image aesthetics and low-level visual features…

Computer Vision and Pattern Recognition · Computer Science 2018-09-26 Tianrong Rao , Min Xu , Dong Xu

Deep learning has achieved remarkable success in medical image analysis, however its adoption in clinical practice is limited by a lack of interpretability. These models often make correct predictions without explaining their reasoning.…

Image and Video Processing · Electrical Eng. & Systems 2025-10-03 Jhonatan Contreras , Thomas Bocklitz

Deep learning has brought significant progress to medical image classification, yet most existing methods still rely on isolated visual evidence and cannot effectively leverage similar cases or external knowledge. In clinical practice,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Yiming Xu , Yixuan Liu , Yuhang Zhang , Ling Zheng , Yihan Wang , Qi Song
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