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With the increasing availability of diverse data types, particularly images and time series data from medical experiments, there is a growing demand for techniques designed to combine various modalities of data effectively. Our motivation…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Ali Rasekh , Reza Heidari , Amir Hosein Haji Mohammad Rezaie , Parsa Sharifi Sedeh , Zahra Ahmadi , Prasenjit Mitra , Wolfgang Nejdl

Early identification of intensive care patients at risk of in-hospital mortality enables timely intervention and efficient resource allocation. Despite high predictive performance, existing machine learning approaches lack transparency and…

Machine Learning · Computer Science 2025-11-21 Alexander Bakumenko , Janine Hoelscher , Hudson Smith

Robust imitation learning using disturbance injections overcomes issues of limited variation in demonstrations. However, these methods assume demonstrations are optimal, and that policy stabilization can be learned via simple augmentations.…

Robotics · Computer Science 2022-05-10 Hirotaka Tahara , Hikaru Sasaki , Hanbit Oh , Brendan Michael , Takamitsu Matsubara

This study investigates the impact of masking strategies on time series imputation models in healthcare settings. While current approaches predominantly rely on random masking for model evaluation, this practice fails to capture the…

Machine Learning · Computer Science 2025-02-05 Linglong Qian , Yiyuan Yang , Wenjie Du , Jun Wang , Richard Dobsoni , Zina Ibrahim

Quantifying relationships between components of a complex system is critical to understanding the rich network of interactions that characterize the behavior of the system. Traditional methods for detecting pairwise dependence of time…

Data Analysis, Statistics and Probability · Physics 2024-04-10 Aria Nguyen , Oscar McMullin , Joseph T. Lizier , Ben D. Fulcher

Time-series experiments, also called switchback experiments or N-of-1 trials, play increasingly important roles in modern applications in medical and industrial areas. Under the potential outcomes framework, recent research has studied…

Methodology · Statistics 2025-10-28 Zhexiao Lin , Peng Ding

Accuracy and interpretability are two dominant features of successful predictive models. Typically, a choice must be made in favor of complex black box models such as recurrent neural networks (RNN) for accuracy versus less accurate but…

Machine Learning · Computer Science 2017-02-28 Edward Choi , Mohammad Taha Bahadori , Joshua A. Kulas , Andy Schuetz , Walter F. Stewart , Jimeng Sun

AI models are often evaluated based on their ability to predict the outcome of interest. However, in many AI for social impact applications, the presence of an intervention that affects the outcome can bias the evaluation. Randomized…

Machine Learning · Computer Science 2025-11-18 Winston Chen , Michael W. Sjoding , Jenna Wiens

Modern longitudinal studies collect feature data at many timepoints, often of the same order of sample size. Such studies are typically affected by {dropout} and positivity violations. We tackle these problems by generalizing effects of…

Methodology · Statistics 2022-03-16 Kwangho Kim , Edward H. Kennedy , Ashley I. Naimi

Analysis of longitudinal randomised controlled trials is frequently complicated because patients deviate from the protocol. Where such deviations are relevant for the estimand, we are typically required to make an untestable assumption…

Methodology · Statistics 2018-05-16 Suzie Cro , James R Carpenter , Michael G Kenward

Deep neural networks are applied in more and more areas of everyday life. However, they still lack essential abilities, such as robustly dealing with spatially transformed input signals. Approaches to mitigate this severe robustness issue…

Machine Learning · Computer Science 2024-05-28 Johann Schmidt , Sebastian Stober

Missing data is unavoidable in longitudinal clinical trials, and outcomes are not always normally distributed. In the presence of outliers or heavy-tailed distributions, the conventional multiple imputation with the mixed model with…

Methodology · Statistics 2022-03-22 Siyi Liu , Yilong Zhang , Gregory T Golm , Guanghan , Liu , Shu Yang

Estimating the effects of interventions on patient outcome is one of the key aspects of personalized medicine. Their inference is often challenged by the fact that the training data comprises only the outcome for the administered treatment,…

Advanced systems such as IoT comprise many heterogeneous, interconnected, and autonomous entities operating in often highly dynamic environments. Due to their large scale and complexity, large volumes of monitoring data are generated and…

Software Engineering · Computer Science 2020-04-09 Lucas Sakizloglou , Sona Ghahremani , Thomas Brand , Matthias Barkowsky , Holger Giese

Empirical analyses on income and wealth inequality and those in other fields in economics and finance often face the difficulty that the data is heterogeneous, heavy-tailed or correlated in some unknown fashion. The paper focuses on…

Econometrics · Economics 2021-11-23 Rustam Ibragimov , Paul Kattuman , Anton Skrobotov

Time series data in real-world applications such as healthcare, climate modeling, and finance are often irregular, multimodal, and messy, with varying sampling rates, asynchronous modalities, and pervasive missingness. However, existing…

Machine Learning · Computer Science 2025-10-16 Ching Chang , Jeehyun Hwang , Yidan Shi , Haixin Wang , Wen-Chih Peng , Tien-Fu Chen , Wei Wang

Observational data in medicine arise as a result of the complex interaction between patients and the healthcare system. The sampling process is often highly irregular and itself constitutes an informative process. When using such data to…

Machine Learning · Computer Science 2022-05-27 Vincent Jeanselme , Glen Martin , Niels Peek , Matthew Sperrin , Brian Tom , Jessica Barrett

We consider a longitudinal data structure consisting of baseline covariates, time-varying treatment variables, intermediate time-dependent covariates, and a possibly time dependent outcome. Previous studies have shown that estimating the…

Statistics Theory · Mathematics 2018-10-09 Linh Tran , Maya Petersen , Joshua Schwab , Mark J van der Laan

During an infectious disease outbreak, public health decision-makers require real-time monitoring of disease transmission to respond quickly and intelligently. In these settings, a key measure of transmission is the instantaneous…

Methodology · Statistics 2025-02-07 Gary Hettinger , David Rubin , Jing Huang

We demonstrate a simple strategy to cope with missing data in sequential inputs, addressing the task of multilabel classification of diagnoses given clinical time series. Collected from the pediatric intensive care unit (PICU) at Children's…

Machine Learning · Computer Science 2016-11-14 Zachary C. Lipton , David C. Kale , Randall Wetzel