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We consider an epidemiological model that includes waning and boosting of immunity. Assuming that repeated exposure to the pathogen fully restores immunity, we derive an SIRS-type model with discrete and distributed delays. First we prove…

Dynamical Systems · Mathematics 2016-06-14 Maria Vittoria Barbarossa , Monika Polner , Gergely Röst

We consider an epidemiological SIR model with an infection rate depending on the recovered population. We establish sufficient conditions for existence, uniqueness, and stability (local and global) of endemic equilibria and consider also…

Classical Analysis and ODEs · Mathematics 2021-07-09 Andres David Báez-Sánchez , Nara Bobko

\noindent We formulate an age-structured three-staged nonlinear partial differential equation model that features {\it nonlinear} recidivism to the infected ({\it infectious}) class from the {\it temporarily} recovered class. Equilibria are…

Dynamical Systems · Mathematics 2019-08-07 Fabio Sanchez , Juan G. Calvo , Esteban Segura , Zhilan Feng

Effects of immune delay on symmetric dynamics are investigated within a model of antigenic variation in malaria. Using isotypic decomposition of the phase space, stability problem is reduced to the analysis of a cubic transcendental…

Chaotic Dynamics · Physics 2012-09-21 K. B. Blyuss , Y. N. Kyrychko

We study a multi-group SAIRS-type epidemic model with vaccination. The role of asymptomatic and symptomatic infectious individuals is explicitly considered in the transmission pattern of the disease among the groups in which the population…

Dynamical Systems · Mathematics 2023-05-23 Stefania Ottaviano , Mattia Sensi , Sara Sottile

We show that the basic reproduction number of an SIS patch model with standard incidence is either strictly decreasing and strictly convex with respect to the diffusion coefficient of infected subpopulation if the patch reproduction numbers…

Populations and Evolution · Quantitative Biology 2020-01-03 Daozhou Gao , Chao-Ping Dong

In this paper, the main purpose is to explore an SIRS epidemic model with a general nonlinear incidence rate $f(I)S=\beta I(1+\upsilon I^{k-1})S$ ($k>0$). We analyzed the existence and stability of equilibria of the epidemic model. Local…

Dynamical Systems · Mathematics 2025-11-03 Xiaoling Wang , Kuilin Wu

Undulation of infection levels, usually called waves, are not well understood. In this paper we propose a mathematical model that exhibits undulation and decay towards a stable state. The model is a re-interpretation of the original…

Populations and Evolution · Quantitative Biology 2022-06-08 Niko Sauer

Transmission dynamics of infectious diseases are often studied using compartmental mathematical models, which are commonly represented as systems of autonomous ordinary differential equations. A key step in the analysis of such models is to…

Populations and Evolution · Quantitative Biology 2025-12-15 David J. D. Earn , C. Connell McCluskey

We investigate the global dynamics of a general Kermack-McKendrick-type epidemic model formulated in terms of a system of renewal equations. Specifically, we consider a renewal model for which both the force of infection and the infected…

Populations and Evolution · Quantitative Biology 2018-10-04 Michael T. Meehan , Daniel G. Cocks , Johannes Müller , Emma S. McBryde

We propose and analyze a nonlinear age-structured multi-species model that serves as a unifying framework for ecological and biotechnological systems in complex environments (microbial communities, bioreactors, and others). The formulation…

Analysis of PDEs · Mathematics 2025-09-23 Marius Bargo , Yacouba Simpore

We study an SIR epidemic model with a seasonal contact rate and saturated treatment function. It is shown that the basic reproduction number $(\mathcal {R}_0)$ cannot be acted as a threshold that predicts the spread of an infection. Based…

Classical Analysis and ODEs · Mathematics 2014-01-06 Zhenguo Bai , Yicang Zhou

We propose a compartmental model for a disease with temporary immunity and secondary infections. From our assumptions on the parameters involved in the model, the system naturally evolves in three time scales. We characterize the equilibria…

Dynamical Systems · Mathematics 2024-04-10 Panagiotis Kaklamanos , Andrea Pugliese , Mattia Sensi , Sara Sottile

We study an infection-age structured epidemic model in which both the infectivity and the rate of loss of immunity depend on the time-since-infection. The model can be equivalently viewed as a nonlinear renewal equation for the incidence of…

Dynamical Systems · Mathematics 2025-11-13 Francesca Scarabel , Harry Coldwell , Tyler Cassidy

In this chapter, we consider a reaction-diffusion SVIR infection model with dis-tributed delay and nonlinear incidence rate. The wellposedness of the proposed model is proved. By means of Lyapunov functionals, we show that the disease-free…

Dynamical Systems · Mathematics 2025-03-10 Achraf Zinihi , Mostafa Tahiri , Moulay Rchid Sidi Ammi

We developed a nonlinear differential equation model to explore the dynamics of relapse phenomena. Our incidence rate function is formulated, taking inspiration from recent adaptive algorithms. It incorporates contact behavior for…

Dynamical Systems · Mathematics 2023-06-27 Jimmy Calvo-Monge , Fabio Sanchez , Juan G. Calvo , Darío Mena

This research gives a thorough examination of an HIV infection model that includes quiescent cells and immune response dynamics in the host. The model, represented by a system of ordinary differential equations, captures the complex…

Populations and Evolution · Quantitative Biology 2025-03-04 Ibrahim Nali , Attila Dénes , Abdessamad Tridane , Xueyong Zhou

In this work we study the stability properties of the equilibrium points of deterministic epidemic models with nonconstant population size. Models with nonconstant population have been studied in the past only in particular cases, two of…

Optimization and Control · Mathematics 2022-02-25 Florin Avram , Rim Adenane , Lasko Basnarkov , Gianluca Bianchin , Dan Goreac , Andrei Halanay

In this paper we consider an SIRS epidemic model under a general assumption of density-dependent mortality. We prove the global stability of the disease-free equilibrium and propose a Lyapunov function that allows to demonstrate the global…

Dynamical Systems · Mathematics 2018-12-31 Alberto d'Onofrio , Piero Manfredi , Ernesto Salinelli

In this paper, we consider a compartmental SIRS epidemic model with asymptomatic infection and seasonal succession, which is a periodic discontinuous differential system. The basic reproduction number $\mathcal{R}_0$ is defined and valuated…

Dynamical Systems · Mathematics 2017-08-15 Yilei Tang , Dongmei Xiao , Weinian Zhang , Di Zhu