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Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

Quantitative Methods · Quantitative Biology 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

The medical imaging community generates a wealth of datasets, many of which are openly accessible and annotated for specific diseases and tasks such as multi-organ or lesion segmentation. Current practices continue to limit model training…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Constantin Ulrich , Fabian Isensee , Tassilo Wald , Maximilian Zenk , Michael Baumgartner , Klaus H. Maier-Hein

In the diverse field of medical imaging, automatic segmentation has numerous applications and must handle a wide variety of input domains, such as different types of Computed Tomography (CT) scans and Magnetic Resonance (MR) images. This…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Chengyin Li , Hui Zhu , Rafi Ibn Sultan , Hassan Bagher Ebadian , Prashant Khanduri , Chetty Indrin , Kundan Thind , Dongxiao Zhu

We present a new instance segmentation approach tailored to biological images, where instances may correspond to individual cells, organisms or plant parts. Unlike instance segmentation for user photographs or road scenes, in biological…

Computer Vision and Pattern Recognition · Computer Science 2020-04-24 Victor Kulikov , Victor Lempitsky

For 3D medical image (e.g. CT and MRI) segmentation, the difficulty of segmenting each slice in a clinical case varies greatly. Previous research on volumetric medical image segmentation in a slice-by-slice manner conventionally use the…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Wenxuan Wang , Chen Chen , Jing Wang , Sen Zha , Yan Zhang , Jiangyun Li

Image segmentation, one of the most critical vision tasks, has been studied for many years. Most of the early algorithms are unsupervised methods, which use hand-crafted features to divide the image into many regions. Recently, owing to the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-11 Qinghong Lin , Weichan Zhong , Jianglin Lu

X-Ray image enhancement, along with many other medical image processing applications, requires the segmentation of images into bone, soft tissue, and open beam regions. We apply a machine learning approach to this problem, presenting an…

Computer Vision and Pattern Recognition · Computer Science 2019-04-23 Joseph Bullock , Carolina Cuesta-Lazaro , Arnau Quera-Bofarull

Automated segmentation proves to be a valuable tool in precisely detecting tumors within medical images. The accurate identification and segmentation of tumor types hold paramount importance in diagnosing, monitoring, and treating highly…

Image and Video Processing · Electrical Eng. & Systems 2024-03-15 Fadillah Maani , Anees Ur Rehman Hashmi , Mariam Aljuboory , Numan Saeed , Ikboljon Sobirov , Mohammad Yaqub

The task of clustering a set of objects based on multiple sources of data arises in several modern applications. We propose an integrative statistical model that permits a separate clustering of the objects for each data source. These…

Machine Learning · Statistics 2015-12-01 Eric F. Lock , David B. Dunson

A single biomedical image can be meaningfully segmented in multiple ways, depending on the desired application. For instance, a brain MRI can be segmented according to tissue types, vascular territories, broad anatomical regions,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Marianne Rakic , Siyu Gai , Etienne Chollet , John V. Guttag , Adrian V. Dalca

We introduce a highly efficient method for panoptic segmentation of large 3D point clouds by redefining this task as a scalable graph clustering problem. This approach can be trained using only local auxiliary tasks, thereby eliminating the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-08 Damien Robert , Hugo Raguet , Loic Landrieu

Whole brain segmentation using deep learning (DL) is a very challenging task since the number of anatomical labels is very high compared to the number of available training images. To address this problem, previous DL methods proposed to…

Image and Video Processing · Electrical Eng. & Systems 2019-11-22 Pierrick Coupé , Boris Mansencal , Michaël Clément , Rémi Giraud , Baudouin Denis de Senneville , Vinh-Thong Ta , Vincent Lepetit , José V. Manjon

The segmentation of satellite images is a necessary step to perform object-oriented image classification, which has become relevant due to its applicability on images with a high spatial resolution. To perform object-oriented image…

Image and Video Processing · Electrical Eng. & Systems 2018-01-18 Wuilan Torres , Antonio Rueda-Toicen

Deep learning models have shown promising performance for cell nucleus segmentation in the field of pathology image analysis. However, training a robust model from multiple domains remains a great challenge for cell nucleus segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Dawei Fan , Yifan Gao , Jiaming Yu , Yanping Chen , Wencheng Li , Chuancong Lin , Kaibin Li , Changcai Yang , Riqing Chen , Lifang Wei

Increasing data set sizes of 3D microscopy imaging experiments demand for an automation of segmentation processes to be able to extract meaningful biomedical information. Due to the shortage of annotated 3D image data that can be used for…

Image and Video Processing · Electrical Eng. & Systems 2022-02-02 Dennis Eschweiler , Richard S. Smith , Johannes Stegmaier

We take an image science perspective on the problem of determining brain network connectivity given functional activity. But adapting the concept of image resolution to this problem, we provide a new perspective on network partitioning for…

Neurons and Cognition · Quantitative Biology 2020-02-14 Keith Dillon , Yu-Ping Wang

Deep learning for medical image classification faces three major challenges: 1) the number of annotated medical images for training are usually small; 2) regions of interest (ROIs) are relatively small with unclear boundaries in the whole…

Computer Vision and Pattern Recognition · Computer Science 2019-10-23 Shaohua Li , Yong Liu , Xiuchao Sui , Cheng Chen , Gabriel Tjio , Daniel Shu Wei Ting , Rick Siow Mong Goh

Spectral clustering is one of the most popular clustering methods. However, how to balance the efficiency and effectiveness of the large-scale spectral clustering with limited computing resources has not been properly solved for a long…

Machine Learning · Computer Science 2022-07-12 Hongmin Li , Xiucai Ye , Akira Imakura , Tetsuya Sakurai

For many image clustering problems, replacing raw image data with features extracted by a pretrained convolutional neural network (CNN), leads to better clustering performance. However, the specific features extracted, and, by extension,…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Joris Guérin , Byron Boots

Recently, automated medical image segmentation methods based on deep learning have achieved great success. However, they heavily rely on large annotated datasets, which are costly and time-consuming to acquire. Few-shot learning aims to…

Artificial Intelligence · Computer Science 2024-08-20 Jiayu Huo , Ruiqiang Xiao , Haotian Zheng , Yang Liu , Sebastien Ourselin , Rachel Sparks