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Reducing the number of experimental units is one of the three pillars of the 3R principles (Replace, Reduce, Refine) in animal research. At the same time, statistical error rates need to be controlled to enable reliable inferences and…

Methodology · Statistics 2026-05-08 Leonhard Held , Fadoua Balabdaoui , Saverio Fontana , Samuel Pawel

Many applications of machine learning methods involve an iterative protocol in which data are collected, a model is trained, and then outputs of that model are used to choose what data to consider next. For example, one data-driven approach…

Machine Learning · Computer Science 2025-04-07 Clara Fannjiang , Stephen Bates , Anastasios N. Angelopoulos , Jennifer Listgarten , Michael I. Jordan

With the pandemic, many experimental psychologists and linguists have started to collect data over the internet (hereafter on-line data). The feasibility of such experiments and the sample sizes required to achieve sufficient statistical…

Computation and Language · Computer Science 2024-03-26 Bürki Audrey , Vasishth Shravan

An ongoing "reproducibility crisis" calls into question scientific discoveries across a variety of disciplines ranging from life to social sciences. Replication studies aim to investigate the validity of findings in published research, and…

Applications · Statistics 2023-05-09 Konstantinos Bourazas , Guido Consonni , Laura Deldossi

Aircraft performance models play a key role in airline operations, especially in planning a fuel-efficient flight. In practice, manufacturers provide guidelines which are slightly modified throughout the aircraft life cycle via the tuning…

Applications · Statistics 2021-02-05 Florent Dewez , Benjamin Guedj , Vincent Vandewalle

Suppose data are fitted to some parametric model but that the true model happens to be one with an additional parameter. When a parameter is to be estimated one can use likelihood estimation in the wider model or in the narrow model.…

Methodology · Statistics 2026-03-27 Nils Lid Hjort

Bayesian inference and the use of posterior or posterior predictive probabilities for decision making have become increasingly popular in clinical trials. The current practice in Bayesian clinical trials relies on a hybrid…

Methodology · Statistics 2024-04-30 Shirin Golchi , James Willard

In this paper, we develop an approach for the exact determination of the minimum sample size for estimating the parameter of an integer-valued random variable, which is parameterized by its expectation. Under some continuity and unimodal…

Statistics Theory · Mathematics 2012-11-20 Xinjia Chen , Zhengjia Chen

Modeling how a robot interacts with the environment around it is an important prerequisite for designing control and planning algorithms. In fact, the performance of controllers and planners is highly dependent on the quality of the model.…

Machine Learning · Computer Science 2020-03-03 Clark Zhang , Arbaaz Khan , Santiago Paternain , Alejandro Ribeiro

We initiate an investigation of private sampling from distributions. Given a dataset with $n$ independent observations from an unknown distribution $P$, a sampling algorithm must output a single observation from a distribution that is close…

Machine Learning · Computer Science 2022-11-16 Sofya Raskhodnikova , Satchit Sivakumar , Adam Smith , Marika Swanberg

A common problem in analysis of experiments or in lattice QCD simulations is fitting a parameterized model to the average over a number of samples of correlated data values. If the number of samples is not infinite, estimates of the…

High Energy Physics - Lattice · Physics 2008-08-27 D. Toussaint , W. Freeman

Sequential Multiple-Assignment Randomized Trials (SMARTs) play an increasingly important role in psychological and behavioral health research. This experimental approach enables researchers to answer scientific questions about how to…

Methodology · Statistics 2023-06-21 John J. Dziak , Daniel Almirall , Walter Dempsey , Catherine Stanger , Inbal Nahum-Shani

Pilot feasibility studies play a pivotal role in the development of clinical trials for rare diseases, where small populations and slow recruitment often threaten trial viability. While such studies are commonly used to assess operational…

Applications · Statistics 2025-07-15 Lara Maleyeff , Valérie Leclair , Shirin Golchi , Marie Hudson

This work presents a statistically principled method for estimating the required number of instances in the experimental comparison of multiple algorithms on a given problem class of interest. This approach generalises earlier results by…

Methodology · Statistics 2019-08-06 Felipe Campelo , Elizabeth F. Wanner

Stochastic traffic capacity is used in traffic modelling and control for unidirectional sections of road infrastructure, although some of the estimation methods have recently proved flawed. However, even sound estimation methods require…

Applications · Statistics 2026-02-24 Igor Mikolasek

As the most important tool to provide high-level evidence-based medicine, researchers can statistically summarize and combine data from multiple studies by conducting meta-analysis. In meta-analysis, mean differences are frequently used…

Methodology · Statistics 2018-01-30 Dehui Luo , Xiang Wan , Jiming Liu , Tiejun Tong

Scientific experiments study interventions that show evidence of an effect size that is meaningfully large, negligibly small, or inconclusively broad. Previously, we proposed contra-analysis as a decision-making process to help determine…

Methodology · Statistics 2023-03-17 Bruce A. Corliss , Yaotian Wang , Heman Shakeri , Philip E. Bourne

We compute bias, variance, and approximate confidence intervals for the efficiency of a random selection process under various special conditions that occur in practical data analysis. We consider the following cases: a) the number of…

Applications · Statistics 2023-11-30 Hans Dembinski , Michael Schmelling

When a scientist performs an experiment they normally acquire a set of measurements and are expected to demonstrate that their results are "statistically significant" thus confirming whatever hypothesis they are testing. The main method for…

Other Statistics · Statistics 2011-09-30 Jacob Levman

We consider planning longitudinal covariate measurements in follow-up studies where covariates are time-varying. We assume that the entire cohort cannot be selected for longitudinal measurements due to financial limitations and study how a…

Methodology · Statistics 2024-07-03 Jaakko Reinikainen , Juha Karvanen