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Mesoporous silica particles have been synthesized by sol-gel method from tetraethoxysilane (tetraethylorthosilicate, TEOS) and methyltriethoxysilane (MTES), in ethanol and water mixture, at different ratios of the of the silica precursors.…

Mesoporous silica particles are promising candidates for drug delivery applications. In this paper, we first synthesize mesoporous silica MCM-41 and its derivative MCM-41GA with anchored glutaraldehyde bridges, and characterize them using a…

Predicting and controlling the transport of colloids in porous media is essential for applications ranging from contaminant remediation to drug delivery. In these complex environments, solute gradients are ubiquitous and could drive…

Soft Condensed Matter · Physics 2026-05-27 Aditya R. Pujari , Amir A. Pahlavan

Soft acoustic metamaterials utilizing mesoporous structures have recently been proposed as a novel means for tuning the overall effective properties of the metamaterial and providing better coupling to the surrounding air. In this work, the…

We present an innovative template-free water-based sol-gel method to produce uniform mesoporous silica beads of millimeter size, which have tunable size, stiffness and porosity, and could be used for adsorption applications. Our protocol…

Soft Condensed Matter · Physics 2025-02-03 M. Milani , K. Ahmad , E. Cavalletti , C. Ligoure , L. Cipelletti , M. Kongkaew , P. Trens , L. Ramos

Tuberculosis remains today a major public health issue with a total of 9 million new cases and 2 million deaths annually. The lack of an effective vaccine and the increasing emergence of new strains of Mycobacterium tuberculosis (Mtb)…

It is shown that porous spherical particles can be obtained via the freezing of silica nanoparticle aqueous suspensions emulsified in a continuous oil phase. After two freeze-thaw cycles, nanoparticles turn aggregated into flocculated…

Soft Condensed Matter · Physics 2020-05-26 Mathieu Nespoulous , Mickaël Antoni , Carine Chassigneux , Renaud Denoyel

Mesoporous silica nanoparticles (MSNs) attract increasing interest in the field of gene and drug delivery due to their versatile features as a multifunctional drug delivery platform. Here, we describe poly(amidoamine) (PAMAM)…

A new general route for siRNA delivery is presented combining porous core-shell silica nanocarriers with a modularly designed multifunctional block copolymer. Specifically, the internal storage and release of siRNA from mesoporous silica…

Subcellular Processes · Quantitative Biology 2016-03-23 Karin Moeller , Katharina Mueller , Hanna Engelke , Christoph Braeuchle , Ernst Wagner , Thomas Bein

The adsorption of lysozyme, cytochrome c and myoglobin, similar-sized globular proteins of approximately 1.5 nm radius, into the mesoporous silica material Santa Barbara Amorphous-15 (SBA-15) with 3.3 nm mean pore radius has been studied…

Soft Condensed Matter · Physics 2015-12-15 Sebastian T. Moerz , Patrick Huber

Surface modified amorphous nanoporous silica molecules with hydrophobic as well as hydrophilic character can be effectively used as therapeutic drug for combating chicken malaria in poultry industry. The amorphous nanosilica was developed…

Understanding how colloids move in crowded environments is key for gaining control over their transport in applications such as drug delivery, filtration, contaminant/microplastic remediation and agriculture. The classical models of colloid…

Soft Condensed Matter · Physics 2026-04-15 Mobin Alipour , Yiran Li , Haoyu Liu , Amir A. Pahlavan

Mesoporous silica particles of MCM-41 type were synthesized by sol-gel method from tetraethyl orthosilicate (TEOS) in 2-methoxyethanol and deionized water mixture in base conditions at room temperature. Ammonia or sodium hydroxides were…

Mesoporous silica nanoparticles have been reported as suitable drug carriers, but their successful delivery to target tissues following systemic administration remains a challenge. In the present work, ultrasound-induced inertial cavitation…

Tissues and Organs · Quantitative Biology 2021-03-18 JL Paris , C Mannris , M Cabanas , R Calisle , M Manzano , M Vallet-Regi , CC Coussios

Acid-induced release of stored ions from polyacrylic acid hydrogels (with a free surface fully permeable to the ion and acid flux) was observed to increase the gel osmotic pressure that leads to rapid, temporary swelling faster than the…

Soft Condensed Matter · Physics 2024-01-24 Chinmay Katke , Peter A. Korevaar , C. Nadir Kaplan

Stratospheric aerosol injection (SAI) using solid particles has been proposed as an alternative to sulfate aerosols for solar radiation modification, but practical deployment faces challenges in efficiently deagglomerating and dispersing…

We present several recently synthesized nanocomposites consisting of liquid crystals as well as an organic molecular crystal embedded into the nanochannels of mesoporous alumina and silica. As liquid-crystalline mesogens achiral, nematogen…

Nanoparticle drug carriers play an important role in facilitating efficient targeted drug delivery, i.e., improving treatment success and reducing drug costs and side effects. However, the mobility of nanoparticle drug carriers poses a…

In this work we investigate the use of nanoporous carrier as drug delivery systems for hydrophobic molecules. By studying a model system made of porous silicon loaded with beta-carotene, we unveil a fundamental limitation of these carriers…

Soft Condensed Matter · Physics 2020-01-23 Chiara Piotto , Paolo Bettotti

The study of dispersion of solid wastes through a porous media is important in order to estimate the ecological impact that, in particular, a radioactive solid waste could produce when it spreads in the soil. There are some models available…

Chemical Physics · Physics 2012-12-05 Estela Mayoral , Eduardo De La Cruz , Luis Carlos Longoria , Eduardo Nahmad-Achar
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