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The advent of large-scale and high-density extracellular recording devices allows simultaneous recording from thousands of neurons. However, the complexity and size of the data makes it mandatory to develop robust algorithms for fully…

Neurons and Cognition · Quantitative Biology 2019-12-03 Gerrit Hilgen

Signals recorded from neurons with extracellular planar sensors have a wide range of waveforms and amplitudes. This variety is a result of different physical conditions affecting the ion currents through a cellular membrane. The…

Emerging non-volatile memory (NVM), or memristive, devices promise energy-efficient realization of deep learning, when efficiently integrated with mixed-signal integrated circuits on a CMOS substrate. Even though several algorithmic…

Neural and Evolutionary Computing · Computer Science 2018-04-23 Vishal Saxena , Xinyu Wu , Kehan Zhu

Although deep encoder-decoder networks have achieved astonishing performance for mitochondria segmentation from electron microscopy (EM) images, they still produce coarse segmentations with lots of discontinuities and false positives.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-30 Zhimin Yuan , Jiajin Yi , Zhengrong Luo , Zhongdao Jia , Jialin Peng

We investigate the microscopic contact of a cell/semiconductor hybrid. The semiconductor is nanostructured with the aim of single channel recording of ion channels in cell membranes. This approach will overcome many limitations of the…

Soft Condensed Matter · Physics 2007-05-23 N. Fertig , A. Tilke , R. H. Blick , J. P. Kotthaus , J. C. Behrends , G. ten Bruggencate

In the intact brain, neural activity can be recorded using sensing electrodes and manipulated using light stimulation. Silicon probes with integrated electrodes and micro-LEDs enable the detection and control of neural activity using a…

Signal Processing · Electrical Eng. & Systems 2022-11-28 Alexander Tarnavsky Eitan , Shirly Someck , Mario Zajac , Eran Socher , Eran Stark

Measurements of neuronal activity across brain areas are important for understanding the neural correlates of cognitive and motor processes like attention, decision-making, and action selection. However, techniques that allow cellular…

Nanoelectromechanical systems, or NEMS, are MEMS scaled to submicron dimensions. In this size regime, it is possible to attain extremely high fundamental frequencies while simultaneously preserving very high mechanical responsivity (small…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 M. L. Roukes

Accurate and robust recording and decoding from the central nervous system (CNS) is essential for advances in human-machine interfacing. However, technologies used to directly measure CNS activity are limited by their resolution,…

Neurons and Cognition · Quantitative Biology 2025-09-19 Jaime Ibáñez , Blanka Zicher , Etienne Burdet , Stuart N. Baker , Carsten Mehring , Dario Farina

Recent years have seen dramatic progress in the development of techniques for measuring the activity and connectivity of large populations of neurons in the brain. However, as these techniques grow ever more powerful---allowing us to even…

Neurons and Cognition · Quantitative Biology 2017-10-20 Thomas Dean

We have calculated the key characteristics of associative (content-addressable) spatial-temporal memories based on neuromorphic networks with restricted connectivity - "CrossNets". Such networks may be naturally implemented in…

Neural and Evolutionary Computing · Computer Science 2017-07-14 Dmitri Gavrilov , Dmitri Strukov , Konstantin K. Likharev

As optical telecommunication networks become more complex, there is an emerging need for systems capable of very complex switching and manipulation of large numbers of optical signals. MEMS enable these systems by combining excellent…

EEG is a non-invasive, safe, and low-risk method to record electrophysiological signals inside the brain. Especially with recent technology developments like dry electrodes, consumer-grade EEG devices, and rapid advances in machine…

Machine Learning · Computer Science 2025-06-23 Tri Duc Ly , Gia H. Ngo

The emergence of resistive non-volatile memories opens the way to highly energy-efficient computation near- or in-memory. However, this type of computation is not compatible with conventional ECC, and has to deal with device unreliability.…

Emerging Technologies · Computer Science 2020-07-14 Marc Bocquet , Tifenn Hirtzlin , Jacques-Olivier Klein , Etienne Nowak , Elisa Vianello , Jean-Michel Portal , Damien Querlioz

Constant envelope (CE) precoding design is of great interest for massive multiuser multi-input multi-output systems because it can significantly reduce hardware cost and power consumption. However, existing CE precoding algorithms are…

Signal Processing · Electrical Eng. & Systems 2020-06-30 Yunfeng He , Hengtao , He , Chao-Kai Wen , Shi Jin

The ultimate goal of this research proposal is the creation of a micro-optomechanical intelligence. The proposal centers on the development and investigation of very large-scale integrated (VLSI) arrays of coupled M/NEMS devices as…

Mesoscale and Nanoscale Physics · Physics 2023-04-14 Samer Houri , Gaetan Kerschen

The living body is composed of innumerable fine and complex structures and although these structures have been studied in the past, a vast amount of information pertaining to them still remains unknown. When attempting to observe these…

Medical Physics · Physics 2021-11-30 Raku Son , Kenji Yamazawa , Akiko Oguchi , Mitsuo Suga , Masaru Tamura , Yasuhiro Murakawa , Satoshi Kume

The advent of advanced neuronal interfaces offers great promise for linking brain functions to electronics. A major bottleneck in achieving this is real-time processing of big data that imposes excessive requirements on bandwidth, energy…

Emerging Technologies · Computer Science 2015-07-27 Isha Gupta , Alexantrou Serb , Ali Khiat , Ralf Zeitler , Stefano Vassanelli , Themistoklis Prodromakis

Robots and autonomous systems require an understanding of complex events (CEs) from sensor data to interact with their environments and humans effectively. Traditional end-to-end neural architectures, despite processing sensor data…

Artificial Intelligence · Computer Science 2024-03-05 Liying Han , Mani B. Srivastava

Despite all the progress of semiconductor integrated circuit technology, the extreme complexity of the human cerebral cortex makes the hardware implementation of neuromorphic networks with a comparable number of devices exceptionally…

Emerging Technologies · Computer Science 2015-05-20 Mirko Prezioso , Farnood Merrikh-Bayat , Brian Hoskins , Gina Adam , Konstantin K. Likharev , Dmitri B. Strukov