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Forecasting transmission of infectious diseases, especially for vector-borne diseases, poses unique challenges for researchers. Behaviors of and interactions between viruses, vectors, hosts, and the environment each play a part in…
Modern Internet services, such as those at Google, Yahoo!, and Amazon, handle billions of requests per day on clusters of thousands of computers. Because these services operate under strict performance requirements, a statistical…
Infectious disease outbreaks recapitulate biology: they emerge from the multi-level interaction of hosts, pathogens, and their shared environment. As a result, predicting when, where, and how far diseases will spread requires a complex…
The relationship between epidemiology, mathematical modeling and computational tools allows to build and test theories on the development and battling of a disease. This PhD thesis is motivated by the study of epidemiological models applied…
A model for the transmission of dengue disease is presented. It consists of eight mutually-exclusive compartments representing the human and vector dynamics. It also includes a control parameter (insecticide) in order to fight the…
Human mobility is one of the key factors at the basis of the spreading of diseases in a population. Containment strategies are usually devised on movement scenarios based on coarse-grained assumptions. Mobility phone data provide a unique…
Infectious disease dynamics operate across multiple biological scales, with within-host viral dynamics being a key driver of between-host transmission. However, while models that explicitly link these scales exist, none have been developed…
The temporal dynamics of social interactions were shown to influence the spread of disease. Here, we model the conditions of progression and competition for several viral strains, exploring various levels of cross-immunity over temporal…
Queuing network control determines the allocation of scarce resources to manage congestion, a fundamental problem in manufacturing, communications, and healthcare. Compared to standard RL problems, queueing problems are distinguished by…
In mathematical epidemiology, epidemic control often aims at driving the number of infected individuals to zero, asymptotically. However , during the transitory phase, the number of infected can peak at high values. In this paper, we…
During an epidemic control, the containment of the disease is usually achieved through increasing devoted resource to shorten the duration of infectiousness. However, the impact of this resource expenditure has not been studied…
Vector-borne epidemics are the result of the combination of different factors such as the crossed contagions between humans and vectors, their demographic distribution and human mobility among others. The current availability of information…
Mosquito-borne diseases cause several hundred thousand deaths every year. Deciphering mosquito host-seeking behavior is essential to prevent disease transmission through mosquito capture and surveillance. Despite recent substantial…
This work aims to assess the risks of Covid-19 disease spread in diverse daily-life situations (referred to as scenarios) involving crowds of maskless pedestrians, mostly outdoors. More concretely, we develop a method to infer the global…
With approximately half of the world's population at risk of contracting dengue, this mosquito-borne disease is of global concern. International travellers significantly contribute to dengue's rapid and large-scale spread by importing the…
While several non-pharmacological measures have been implemented for a few months in an effort to slow the coronavirus disease (COVID-19) pandemic in the United States, the disease remains a danger in a number of counties as restrictions…
Arboviruses represent a significant threat to human, animal, and plant health worldwide. To elucidate transmission, anticipate their spread and efficiently control them, mechanistic modelling has proven its usefulness. However, most models…
This paper aims to address the integrated routing and appointment scheduling (RAS) problem for a single service provider. The RAS problem is an operational challenge faced by operators that provide services requiring home attendance, such…
The vast majority of strategies aimed at controlling contagion processes on networks considers the connectivity pattern of the system as either quenched or annealed. However, in the real world many networks are highly dynamical and evolve…
Patching nodes is an effective network defense strategy for malware control at early stages, and its performance is primarily dependent on how accurately the infection propagation is characterized. In this paper, we aim to design a novel…