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In the theoretical research of Hepatitis B virus, mathematical models of its transmission mechanism have been thoroughly investigated, while the dynamics of the immune process in vivo have not. At present, nearly all the existing models are…

Chaotic Dynamics · Physics 2019-12-09 Xiaohe Yu , Fei Gao , Xingluan Wang , Jiangtao Zhang

This paper shows the global existence and boundedness of solutions of a reaction diffusion system modeling liver infections. The existence proof is presented step by step and the focus lies on the interpretation of intermediate results in…

Analysis of PDEs · Mathematics 2023-08-02 Cordula Reisch , Dirk Langemann

In this paper, a mathematical analysis of the global dynamics of a partial differential equation viral infection cellular model is carried out. We study the dynamics of a hepatitis C virus (HCV) model, under therapy, that considers both…

Analysis of PDEs · Mathematics 2021-11-08 Alexis Nangue , Bruno Nde Tchiffo

In recent years, discrete fractional epidemic models with reaction-diffusion have become increasingly popular in the literature, not only for its necessity of numerical simulation, but also for its defined physical processes. In this paper,…

Numerical Analysis · Mathematics 2022-08-16 Lu Zhenzhen , Yu Yongguang , Xu Weiyi , Ren Guojian , Meng Xiangyun

In this research, we have derived a mathematical model for within human dynamics of COVID-19 infection using delay differential equations. The new model considers a 'latent period' and 'the time for immune response' as delay parameters,…

Populations and Evolution · Quantitative Biology 2025-01-14 Amar N. Chatterjee , Teklebirhan Abraha , Fahad Al Basir , Delfim F. M. Torres

We investigate an infection-age structured competitive epidemiological model involving multiple strains. While classical results establish competitive exclusion when a unique maximal basic reproduction number exists, we provide here a…

Analysis of PDEs · Mathematics 2026-04-01 Simon Girel , Quentin Richard

This paper is concerned with stability analysis of nonlinear time-varying systems by using Lyapunov function based approach. The classical Lyapunov stability theorems are generalized in the sense that the time-derivative of the Lyapunov…

Dynamical Systems · Mathematics 2017-08-18 Bin Zhou

In this paper, Lyapunov-Razumikhin technique, design of state-dependent switching laws, a fixed point theorem and variational methods are employed to derive the existence and the unique existence results of globally exponentially stable…

Dynamical Systems · Mathematics 2026-01-30 Ruofeng Rao , Jialin Huang , Xiaodi Li

In this paper, we first propose a diffusive pathogen infection model with general incidence rate which incorporates cell-to-cell transmission. By applying the theory of monotone dynamical systems, we prove that the model admits the global…

Analysis of PDEs · Mathematics 2026-02-24 Shohel Ahmed

We study global-in-time behavior of the solution to a reaction-diffusion system with mass conservation, as proposed in the study of cell polarity, particularly, the second model of \cite{oi07}. First, we show global-in-time existence of…

Analysis of PDEs · Mathematics 2015-11-13 Evangelos Latos , Yoshihisa Morita , Takashi Suzuki

Some viruses, such as human immunodeficiency virus, can infect several types of cell populations. The age of infection can also affect the dynamics of infected cells and production of viral particles. In this work, we study a virus model…

Dynamical Systems · Mathematics 2022-09-07 Ángel Cervantes-Pérez , Eric Ávila-Vales

A compartment epidemic model for infectious disease spreading is investigated, where movement of individuals is governed by spatial diffusion. The model includes infection age of the infected individuals and assumes a logistic growth of the…

Analysis of PDEs · Mathematics 2023-06-28 Christoph Walker

In this paper, we examine the long-time dynamics of an epidemic model whose diffusion and reaction terms involve nonlocal effects described by suitable convolution operators.The spreading front of the disease is represented by the free…

Analysis of PDEs · Mathematics 2022-03-01 Rong Wang , Yihong Du

In this paper we consider the stability of a class of deterministic and stochastic SEIRS epidemic models with delay. Indeed, we assume that the transmission rate could be stochastic and the presence of a latency period of $r$ consecutive…

Probability · Mathematics 2017-02-22 Xavier Bardina , Marco Ferrante , Carles Rovira

We study a simple realistic model for describing the diffusion of an infectious disease on a population of individuals. The dynamics is governed by a single functional delay differential equation, which, in the case of a large population,…

Populations and Evolution · Quantitative Biology 2020-09-28 Luca Dell'Anna

In this paper, we are concerned with an epidemic reaction-diffusion system with nonlinear incidence mechanism of the form $S^qI^p\,(p,\,q>0)$. The coefficients of the system are spatially heterogeneous and time dependent (particularly time…

Analysis of PDEs · Mathematics 2021-06-15 Rui Peng , Yixiang Wu

In this paper we consider a delayed nonlinear model of the dynamics of the immune system against a viral infection that contains wild-type virus and one mutant. A finite response time of the immune system was considered in order which leads…

Populations and Evolution · Quantitative Biology 2017-11-22 D. Messias , Iram Gleria , S. S. Albuquerque , Askery Canabarro , H. E. Stanley

In [Math. Comput. Sci. 12 (2018), no. 2, 111--127], a delayed model describing the dynamics of the Human Immunodeficiency Virus (HIV) with Cytotoxic T Lymphocytes (CTL) immune response is investigated by Allali, Harroudi and Torres. Here,…

Dynamical Systems · Mathematics 2022-10-03 Sandra Vaz , Delfim F. M. Torres

This paper involves a diffusive epidemic model whose domain has one free boundary with the Stefan boundary condition, and one fixed boundary subject to the usual homogeneous Dirichlet or Neumann condition. By using the standard upper and…

Analysis of PDEs · Mathematics 2024-05-03 Xueping Li , Lei Li , Ying Xu , DanDan Zhu

In this paper, we consider reaction-diffusion epidemic models with mass action or standard incidence mechanism and study the impact of limiting population movement on disease transmissions. We set either the dispersal rate of the…

Analysis of PDEs · Mathematics 2023-12-19 Rachidi Salako , Yixiang Wu