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Related papers: Dr.VAE: Drug Response Variational Autoencoder

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The combination of machine learning models with physical models is a recent research path to learn robust data representations. In this paper, we introduce p$^3$VAE, a variational autoencoder that integrates prior physical knowledge about…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Romain Thoreau , Laurent Risser , Véronique Achard , Béatrice Berthelot , Xavier Briottet

Variational Autoencoders and Generative Adversarial Networks remained the state-of-the-art (SOTA) generative models until 2022. Now they are superseded by diffusion-based models. Efforts to improve traditional models have stagnated as a…

Machine Learning · Computer Science 2026-03-10 Tuhin Subhra De

Deep generative models have achieved impressive success in recent years. Generative Adversarial Networks (GANs) and Variational Autoencoders (VAEs), as emerging families for generative model learning, have largely been considered as two…

Machine Learning · Computer Science 2018-07-12 Zhiting Hu , Zichao Yang , Ruslan Salakhutdinov , Eric P. Xing

One of the major shortcomings of variational autoencoders is the inability to produce generations from the individual modalities of data originating from mixture distributions. This is primarily due to the use of a simple isotropic Gaussian…

Machine Learning · Computer Science 2019-12-02 Frantzeska Lavda , Magda Gregorová , Alexandros Kalousis

Deep generative models aim to learn underlying distributions that generate the observed data. Given the fact that the generative distribution may be complex and intractable, deep latent variable models use probabilistic frameworks to learn…

Machine Learning · Computer Science 2021-10-05 Batuhan Koyuncu

Modelling the underlying mechanisms of neurodegenerative diseases demands methods that capture heterogeneous and spatially varying dynamics from sparse, high-dimensional neuroimaging data. Integrating partial differential equation (PDE)…

Image and Video Processing · Electrical Eng. & Systems 2025-09-19 Sanduni Pinnawala , Annabelle Hartanto , Ivor J. A. Simpson , Peter A. Wijeratne

In this paper we explore the effect of architectural choices on learning a Variational Autoencoder (VAE) for text generation. In contrast to the previously introduced VAE model for text where both the encoder and decoder are RNNs, we…

Computation and Language · Computer Science 2017-02-09 Stanislau Semeniuta , Aliaksei Severyn , Erhardt Barth

The ability to record activities from hundreds of neurons simultaneously in the brain has placed an increasing demand for developing appropriate statistical techniques to analyze such data. Recently, deep generative models have been…

Machine Learning · Statistics 2020-11-11 Ding Zhou , Xue-Xin Wei

Vector Quantized-Variational AutoEncoders (VQ-VAE) are generative models based on discrete latent representations of the data, where inputs are mapped to a finite set of learned embeddings.To generate new samples, an autoregressive prior…

Machine Learning · Statistics 2022-08-04 Max Cohen , Guillaume Quispe , Sylvain Le Corff , Charles Ollion , Eric Moulines

Latent variable models such as the Variational Auto-Encoder (VAE) have become a go-to tool for analyzing biological data, especially in the field of single-cell genomics. One remaining challenge is the interpretability of latent variables…

Genomics · Quantitative Biology 2023-02-20 Romain Lopez , Nataša Tagasovska , Stephen Ra , Kyunghyn Cho , Jonathan K. Pritchard , Aviv Regev

Instance-based interpretation methods have been widely studied for supervised learning methods as they help explain how black box neural networks predict. However, instance-based interpretations remain ill-understood in the context of…

Machine Learning · Computer Science 2022-01-25 Zhifeng Kong , Kamalika Chaudhuri

Learning interpretable and disentangled representations of data is a key topic in machine learning research. Variational Autoencoder (VAE) is a scalable method for learning directed latent variable models of complex data. It employs a clear…

Machine Learning · Computer Science 2020-06-04 Andriy Serdega , Dae-Shik Kim

Variational Auto-encoders (VAEs) are deep generative latent variable models consisting of two components: a generative model that captures a data distribution p(x) by transforming a distribution p(z) over latent space, and an inference…

Machine Learning · Computer Science 2022-08-25 Yaniv Yacoby , Weiwei Pan , Finale Doshi-Velez

We present an autoencoder that leverages learned representations to better measure similarities in data space. By combining a variational autoencoder with a generative adversarial network we can use learned feature representations in the…

Machine Learning · Computer Science 2016-02-12 Anders Boesen Lindbo Larsen , Søren Kaae Sønderby , Hugo Larochelle , Ole Winther

Electron, optical, and scanning probe microscopy methods are generating ever increasing volume of image data containing information on atomic and mesoscale structures and functionalities. This necessitates the development of the machine…

Machine Learning · Computer Science 2023-04-03 Mani Valleti , Yongtao Liu , Sergei Kalinin

The Variational Autoencoder (VAE) is known to suffer from the phenomenon of \textit{posterior collapse}, where the latent representations generated by the model become independent of the inputs. This leads to degenerated representations of…

Machine Learning · Computer Science 2023-09-12 Fotios Lygerakis , Elmar Rueckert

Recently, molecule generation using deep learning has been actively investigated in drug discovery. In this field, Transformer and VAE are widely used as powerful models, but they are rarely used in combination due to structural and…

Biomolecules · Quantitative Biology 2024-04-08 Yasuhiro Yoshikai , Tadahaya Mizuno , Shumpei Nemoto , Hiroyuki Kusuhara

Generally, the performance of deep neural networks (DNNs) heavily depends on the quality of data representation learning. Our preliminary work has emphasized the significance of deep representation learning (DRL) in the context of speech…

Audio and Speech Processing · Electrical Eng. & Systems 2023-12-18 Yang Xiang , Jingguang Tian , Xinhui Hu , Xinkang Xu , ZhaoHui Yin

Video Variational Autoencoder (VAE) enables latent video generative modeling by mapping the visual world into compact spatiotemporal latent spaces, improving training efficiency and stability. While existing video VAEs achieve commendable…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Yian Zhao , Feng Wang , Qiushan Guo , Chang Liu , Xiangyang Ji , Jian Zhang , Jie Chen

Variant effect predictors (VEPs) aim to assess the functional impact of protein variants, traditionally relying on multiple sequence alignments (MSAs). This approach assumes that naturally occurring variants are fit, an assumption…

Machine Learning · Computer Science 2025-07-04 Antoine Honoré , Borja Rodríguez Gálvez , Yoomi Park , Yitian Zhou , Volker M. Lauschke , Ming Xiao
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