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The physical limit with which a cell senses external ligand concentration corresponds to the perfect absorber, where all ligand particles are absorbed and overcounting of same ligand particles does not occur. Here we analyze how the lateral…
The mitogen-activated protein kinase (MAPK) signaling cascade, an evolutionarily conserved motif present in all eukaryotic cells, is involved in coordinating critical cell-fate decisions, regulating protein synthesis, and mediating learning…
This paper is a continuation of [2] where a new model of biological invasions in the plane directed by a line was introduced. Here we include new features such as transport and reaction terms on the line. Their interaction with the pure…
Both action potentials and mechanosensitive signalling are an important communication mechanisms in plants. Considering an information theoretic framework, this paper explores the effective range of multiple action potentials for a long…
In order to respond to environmental signals, cells often use small molecular circuits to transmit information about their surroundings. Recently, motivated by concrete examples in signaling and gene regulation, a body of work has focused…
In metazoans, cells collectively polarize and align along the tissue plane. This phenomenon is called Planar cell polarity (PCP). Polarization means asymmetric segregation of molecules and sub-cellular structures within a cell. In PCP,…
Cells can be considered as systems that utilize changes in thermodynamic entropy as information. Therefore, they serve as useful models for investigating the relationships between entropy production and information transmission, i.e.,…
The time-changing nature of our world demands processing of huge amounts of information in fast and reliable way to generate successful behaviors. Therefore, significant brain resources are devoted to process spatiotemporal information.…
A multi-user cognitive (secondary) radio system is considered, where the spatial multiplexing mode of operation is implemented amongst the nodes, under the presence of multiple primary transmissions. The secondary receiver carries out…
Mutual information and its causal variant, directed information, have been widely used to quantitatively characterize the performance of biological sensing and information transduction. However, once coupled with selection in response to…
We report a realization of an associative memory signal/information processing system based on simple enzyme-catalyzed biochemical reactions. Optically detected chemical output is always obtained in response to the triggering input, but the…
Biological cells are able to accurately sense chemicals with receptors at their surfaces, allowing cells to move towards sources of attractant and away from sources of repellent. The accuracy of sensing chemical concentration is ultimately…
We look at the problem of signal transduction by extracellular agonist binding to a receptor protein at the membrane (sensor) via binding of G-proteins (effectors) to a highly integrative target molecule, such as the second messenger cAMP…
With vast mmWave spectrum and narrow beam antenna technology, precise position location is now possible in 5G and future mobile communication systems. In this article, we describe how centimeterlevel localization accuracy can be achieved,…
Signaling pathways serve to communicate information about extracellular conditions into the cell, to both the nucleus and cytoplasmic processes to control cell responses. Genetic mutations in signaling network components are frequently…
Robots that can manipulate objects in unstructured environments and collaborate with humans can benefit immensely by understanding natural language. We propose a pipelined architecture of two stages to perform spatial reasoning on the text…
This paper presents a framework for target detection and downlink data transmission in a repeater-assisted bi-static integrated sensing and communication system. A repeater is an active scatterer that retransmits incoming signals with a…
This study investigates the position bias in information retrieval, where models tend to overemphasize content at the beginning of passages while neglecting semantically relevant information that appears later. To analyze the extent and…
With the advent of the 5th generation of wireless standards and an increasing demand for higher throughput, methods to improve the spectral efficiency of wireless systems have become very important. In the context of cognitive radio, a…
Cell decision-making refers to the process by which cells gather information from their local microenvironment and regulate their internal states to create appropriate responses. Microenvironmental cell sensing plays a key role in this…