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A common problem in health research is that we have a large database with many variables measured on a large number of individuals. We are interested in measuring additional variables on a subsample; these measurements may be newly…

Methodology · Statistics 2022-03-22 Thomas Lumley , Tong Chen

Model averaging is an important alternative to model selection with attractive prediction accuracy. However, its application to high-dimensional data remains under-explored. We propose a high-dimensional model averaging method via…

Statistics Theory · Mathematics 2025-06-11 Zhengyan Wan , Fang Fang , Binyan Jiang

We explore the problem of learning under selective labels in the context of algorithm-assisted decision making. Selective labels is a pervasive selection bias problem that arises when historical decision making blinds us to the true outcome…

Machine Learning · Computer Science 2018-07-06 Maria De-Arteaga , Artur Dubrawski , Alexandra Chouldechova

Statistical machine learning models should be evaluated and validated before putting to work. Conventional k-fold Monte Carlo Cross-Validation (MCCV) procedure uses a pseudo-random sequence to partition instances into k subsets, which…

Machine Learning · Statistics 2019-07-05 Liang Guo , Jianya Liu , Ruodan Lu

Today, there are standard and well established procedures within the Human Activity Recognition (HAR) pipeline. However, some of these conventional approaches lead to accuracy overestimation. In particular, sliding windows for data…

Machine Learning · Computer Science 2024-07-11 Andrés Tello , Victoria Degeler , Alexander Lazovik

Imperfect labels limit the quality of predictions learned by deep neural networks. This is particularly relevant in medical image segmentation, where reference annotations are difficult to collect and vary significantly even across expert…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Eugene Vorontsov , Samuel Kadoury

The consideration of predictive uncertainty in medical imaging with deep learning is of utmost importance. We apply estimation of both aleatoric and epistemic uncertainty by variational Bayesian inference with Monte Carlo dropout to…

Image and Video Processing · Electrical Eng. & Systems 2021-04-27 Max-Heinrich Laves , Sontje Ihler , Jacob F. Fast , Lüder A. Kahrs , Tobias Ortmaier

Common cross-validation (CV) methods like k-fold cross-validation or Monte-Carlo cross-validation estimate the predictive performance of a learner by repeatedly training it on a large portion of the given data and testing on the remaining…

Machine Learning · Computer Science 2021-11-30 Felix Mohr , Jan N. van Rijn

The use of deep learning for medical imaging has seen tremendous growth in the research community. One reason for the slow uptake of these systems in the clinical setting is that they are complex, opaque and tend to fail silently. Outside…

Computer Vision and Pattern Recognition · Computer Science 2018-07-03 Terrance DeVries , Graham W. Taylor

Despite the recent improvements in overall accuracy, deep learning systems still exhibit low levels of robustness. Detecting possible failures is critical for a successful clinical integration of these systems, where each data point…

Image and Video Processing · Electrical Eng. & Systems 2019-10-14 Alain Jungo , Mauricio Reyes

Context: Conducting experiments is central to research machine learning research to benchmark, evaluate and compare learning algorithms. Consequently it is important we conduct reliable, trustworthy experiments. Objective: We investigate…

In a standard regression problem, we have a set of explanatory variables whose effect on some response vector is modeled. For wide binary data, such as genetic marker data, we often have two limitations. First, we have more parameters than…

Methodology · Statistics 2021-09-20 Katharina Parry , Leo N. Geppert , Alexander Munteanu , Katja Ickstadt

As neural networks become more popular, the need for accompanying uncertainty estimates increases. There are currently two main approaches to test the quality of these estimates. Most methods output a density. They can be compared by…

Machine Learning · Statistics 2024-06-05 Laurens Sluijterman , Eric Cator , Tom Heskes

Functional neuroimaging can measure the brain?s response to an external stimulus. It is used to perform brain mapping: identifying from these observations the brain regions involved. This problem can be cast into a linear supervised…

Machine Learning · Computer Science 2012-07-03 Gael Varoquaux , Alexandre Gramfort , Bertrand Thirion

Recently, Saeb et al (2017) showed that, in diagnostic machine learning applications, having data of each subject randomly assigned to both training and test sets (record-wise data split) can lead to massive underestimation of the…

Contemporary sample size calculations for external validation of risk prediction models require users to specify fixed values of assumed model performance metrics alongside target precision levels (e.g., 95% CI widths). However, due to the…

Applications · Statistics 2026-02-13 Mohsen Sadatsafavi , Paul Gustafson , Solmaz Setayeshgar , Laure Wynants , Richard D Riley

In applied multivariate statistics, estimating the number of latent dimensions or the number of clusters, $k$, is a fundamental and recurring problem. We study a sequence of statistics called "cross-validated eigenvalues." Under a large…

Methodology · Statistics 2025-12-24 Fan Chen , Sebastien Roch , Karl Rohe , Shuqi Yu

Estimation of causal effects using machine learning methods has become an active research field in econometrics. In this paper, we study the finite sample performance of meta-learners for estimation of heterogeneous treatment effects under…

Econometrics · Economics 2022-02-01 Gabriel Okasa

We develop new methods to integrate experimental and observational data in causal inference. While randomized controlled trials offer strong internal validity, they are often costly and therefore limited in sample size. Observational data,…

Econometrics · Economics 2025-11-04 Xuelin Yang , Licong Lin , Susan Athey , Michael I. Jordan , Guido W. Imbens

This paper tackles the problem of detecting abrupt changes in the mean of a heteroscedastic signal by model selection, without knowledge on the variations of the noise. A new family of change-point detection procedures is proposed, showing…

Methodology · Statistics 2011-02-01 Sylvain Arlot , Alain Celisse