Related papers: Three-dimensional Cardiovascular Imaging-Genetics:…
Diffusion Tensor Cardiac Magnetic Resonance (DT-CMR) is the only in vivo method to non-invasively examine the microstructure of the human heart. Current research in DT-CMR aims to improve the understanding of how the cardiac microstructure…
Accurate reorientation and segmentation of the left ventricular (LV) is essential for the quantitative analysis of myocardial perfusion imaging (MPI), in which one critical step is to reorient the reconstructed transaxial nuclear cardiac…
Automatic labelling of anatomical structures, such as coronary arteries, is critical for diagnosis, yet existing (non-deep learning) methods are limited by a reliance on prior topological knowledge of the expected tree-like structures. As…
We present a new computational model for the numerical simulation of blood flow in the human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian Eulerian formulation to account for the endocardium motion…
This study combines a one-dimensional (1D) model with micro-CT imaging and hemodynamic data to quantify uncertainty of flow and pressure predictions in the pulmonary arteries in a control and hypoxia induced hypertensive mouse. We use local…
Univariate and multivariate methods for association of the genom-ic variations with the end-or-endo phenotype have been widely used for genome wide association studies. In addition to encoding the SNPs, we advocate usage of clustering as a…
Intracardiac flow patterns are shaped by the coupled motion of the cardiac chambers and heart valves and provide important information about cardiac function. However, clinical flow imaging remains limited by exam times, noise, resolution,…
The rhythmic pumping motion of the heart stands as a cornerstone in life, as it circulates blood to the entire human body through a series of carefully timed contractions of the individual chambers. Changes in the size, shape and movement…
Accurate vascular segmentation is essential for coronary visualization and the diagnosis of coronary heart disease. This task involves the extraction of sparse tree-like vascular branches from the volumetric space. However, existing methods…
Fully automatic cardiac segmentation can be a fast and reproducible method to extract clinical measurements from an echocardiography examination. The U-Net architecture is the current state-of-the-art deep learning architecture for medical…
Automatic and accurate whole-heart and great vessel segmentation from 3D cardiac magnetic resonance (MR) images plays an important role in the computer-assisted diagnosis and treatment of cardiovascular disease. However, this task is very…
We propose a fully automated algorithm based on a deep learning framework enabling screening of a coronary computed tomography angiography (CCTA) examination for confident detection of the presence or absence of coronary artery…
Segmentation of the heart in cardiac cine MR is clinically used to quantify cardiac function. We propose a fully automatic method for segmentation and disease classification using cardiac cine MR images. A convolutional neural network (CNN)…
Hemodynamic velocity fields in coronary arteries could be the basis of valuable biomarkers for diagnosis, prognosis and treatment planning in cardiovascular disease. Velocity fields are typically obtained from patient-specific 3D artery…
Convolutional neural networks (CNN) have demonstrated their ability to segment 2D cardiac ultrasound images. However, despite recent successes according to which the intra-observer variability on end-diastole and end-systole images has been…
Accurate representation of myocardial infarct geometry is crucial for patient-specific cardiac modeling in MI patients. While Late gadolinium enhancement (LGE) MRI is the clinical gold standard for infarct detection, it requires contrast…
3D motion estimation from cine cardiac magnetic resonance (CMR) images is important for the assessment of cardiac function and diagnosis of cardiovascular diseases. Most of the previous methods focus on estimating pixel-/voxel-wise motion…
While progress has been made in identifying common genetic variants associated with human diseases, for most of common complex diseases, the identified genetic variants only account for a small proportion of heritability. Challenges remain…
We propose a new method to automatically contour the left ventricle on 2D echocardiographic images. Unlike most existing segmentation methods, which are based on predicting segmentation masks, we focus at predicting the endocardial contour…
Radiological imaging offers effective measurement of anatomy, which is useful in disease diagnosis and assessment. Previous study has shown that the left atrial wall remodeling can provide information to predict treatment outcome in atrial…