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Diffusion Tensor Cardiac Magnetic Resonance (DT-CMR) is the only in vivo method to non-invasively examine the microstructure of the human heart. Current research in DT-CMR aims to improve the understanding of how the cardiac microstructure…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Yinzhe Wu , Jiahao Huang , Fanwen Wang , Pedro Ferreira , Andrew Scott , Sonia Nielles-Vallespin , Guang Yang

Accurate reorientation and segmentation of the left ventricular (LV) is essential for the quantitative analysis of myocardial perfusion imaging (MPI), in which one critical step is to reorient the reconstructed transaxial nuclear cardiac…

Image and Video Processing · Electrical Eng. & Systems 2023-10-17 Yangfan Ni , Duo Zhang , Gege Ma , Lijun Lu , Zhongke Huang , Wentao Zhu

Automatic labelling of anatomical structures, such as coronary arteries, is critical for diagnosis, yet existing (non-deep learning) methods are limited by a reliance on prior topological knowledge of the expected tree-like structures. As…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Yadan Li , Mohammad Ali Armin , Simon Denman , David Ahmedt-Aristizabal

We present a new computational model for the numerical simulation of blood flow in the human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian Eulerian formulation to account for the endocardium motion…

This study combines a one-dimensional (1D) model with micro-CT imaging and hemodynamic data to quantify uncertainty of flow and pressure predictions in the pulmonary arteries in a control and hypoxia induced hypertensive mouse. We use local…

Fluid Dynamics · Physics 2019-10-02 Mitchel J. Colebank , M. Umar Qureshi , Mette S. Olufsen

Univariate and multivariate methods for association of the genom-ic variations with the end-or-endo phenotype have been widely used for genome wide association studies. In addition to encoding the SNPs, we advocate usage of clustering as a…

Quantitative Methods · Quantitative Biology 2021-03-01 Abhishek Narain Singh

Intracardiac flow patterns are shaped by the coupled motion of the cardiac chambers and heart valves and provide important information about cardiac function. However, clinical flow imaging remains limited by exam times, noise, resolution,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Fanwei Kong , Aaron Brown , Michael Loecher , Perry S. Choi , Lei Shi , Michael Ma , Daniel B. Ennis , Alison Marsden

The rhythmic pumping motion of the heart stands as a cornerstone in life, as it circulates blood to the entire human body through a series of carefully timed contractions of the individual chambers. Changes in the size, shape and movement…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Kristine Sørensen , Paula Diez , Jan Margeta , Yasmin El Youssef , Michael Pham , Jonas Jalili Pedersen , Tobias Kühl , Ole de Backer , Klaus Kofoed , Oscar Camara , Rasmus Paulsen

Accurate vascular segmentation is essential for coronary visualization and the diagnosis of coronary heart disease. This task involves the extraction of sparse tree-like vascular branches from the volumetric space. However, existing methods…

Image and Video Processing · Electrical Eng. & Systems 2025-04-21 Bowen Liu , Chunlei Meng , Wei Lin , Hongda Zhang , Ziqing Zhou , Zhongxue Gan , Chun Ouyang

Fully automatic cardiac segmentation can be a fast and reproducible method to extract clinical measurements from an echocardiography examination. The U-Net architecture is the current state-of-the-art deep learning architecture for medical…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Gilles Van De Vyver , Sarina Thomas , Guy Ben-Yosef , Sindre Hellum Olaisen , Håvard Dalen , Lasse Løvstakken , Erik Smistad

Automatic and accurate whole-heart and great vessel segmentation from 3D cardiac magnetic resonance (MR) images plays an important role in the computer-assisted diagnosis and treatment of cardiovascular disease. However, this task is very…

Computer Vision and Pattern Recognition · Computer Science 2017-08-03 Lequan Yu , Jie-Zhi Cheng , Qi Dou , Xin Yang , Hao Chen , Jing Qin , Pheng-Ann Heng

We propose a fully automated algorithm based on a deep learning framework enabling screening of a coronary computed tomography angiography (CCTA) examination for confident detection of the presence or absence of coronary artery…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Sema Candemir , Richard D. White , Mutlu Demirer , Vikash Gupta , Matthew T. Bigelow , Luciano M. Prevedello , Barbaros S. Erdal

Segmentation of the heart in cardiac cine MR is clinically used to quantify cardiac function. We propose a fully automatic method for segmentation and disease classification using cardiac cine MR images. A convolutional neural network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2017-08-04 Jelmer M. Wolterink , Tim Leiner , Max A. Viergever , Ivana Isgum

Hemodynamic velocity fields in coronary arteries could be the basis of valuable biomarkers for diagnosis, prognosis and treatment planning in cardiovascular disease. Velocity fields are typically obtained from patient-specific 3D artery…

Machine Learning · Computer Science 2023-08-07 Julian Suk , Christoph Brune , Jelmer M. Wolterink

Convolutional neural networks (CNN) have demonstrated their ability to segment 2D cardiac ultrasound images. However, despite recent successes according to which the intra-observer variability on end-diastole and end-systole images has been…

Image and Video Processing · Electrical Eng. & Systems 2022-05-09 Nathan Painchaud , Nicolas Duchateau , Olivier Bernard , Pierre-Marc Jodoin

Accurate representation of myocardial infarct geometry is crucial for patient-specific cardiac modeling in MI patients. While Late gadolinium enhancement (LGE) MRI is the clinical gold standard for infarct detection, it requires contrast…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Yilin Lyu , Fan Yang , Xiaoyue Liu , Zichen Jiang , Joshua Dillon , Debbie Zhao , Martyn Nash , Charlene Mauger , Alistair Young , Ching-Hui Sia , Mark YY Chan , Lei Li

3D motion estimation from cine cardiac magnetic resonance (CMR) images is important for the assessment of cardiac function and diagnosis of cardiovascular diseases. Most of the previous methods focus on estimating pixel-/voxel-wise motion…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Qingjie Meng , Wenjia Bai , Tianrui Liu , Declan P O'Regan , Daniel Rueckert

While progress has been made in identifying common genetic variants associated with human diseases, for most of common complex diseases, the identified genetic variants only account for a small proportion of heritability. Challenges remain…

Applications · Statistics 2025-08-18 Olga A. Vsevolozhskaya , Dmitri V. Zaykin , Mark C. Greenwood , Changshuai Wei , Qing Lu

We propose a new method to automatically contour the left ventricle on 2D echocardiographic images. Unlike most existing segmentation methods, which are based on predicting segmentation masks, we focus at predicting the endocardial contour…

Image and Video Processing · Electrical Eng. & Systems 2022-07-14 Alberto Gomez , Mihaela Porumb , Angela Mumith , Thierry Judge , Shan Gao , Woo-Jin Cho Kim , Jorge Oliveira , Agis Chartsias

Radiological imaging offers effective measurement of anatomy, which is useful in disease diagnosis and assessment. Previous study has shown that the left atrial wall remodeling can provide information to predict treatment outcome in atrial…

Computer Vision and Pattern Recognition · Computer Science 2018-12-07 Shuman Jia , Antoine Despinasse , Zihao Wang , Hervé Delingette , Xavier Pennec , Pierre Jaïs , Hubert Cochet , Maxime Sermesant
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