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The rapid development of high-throughput technologies has enabled the generation of data from biological or disease processes that span multiple layers, like genomic, proteomic or metabolomic data, and further pertain to multiple sources,…

Machine Learning · Statistics 2022-01-25 Subhabrata Majumdar , George Michailidis

A central challenge in analyzing multivariate interactions within complex systems is to decompose how multiple inputs jointly determine an output. Existing approaches generally operate on observed probability distributions and can conflate…

Information Theory · Computer Science 2026-03-19 Clifford Bohm , Vincent R. Ragusa , Arend Hintze , Charles Ofria , Emily Dolson , Christoph Adami

Understanding and constructing brain communications that capture dynamic communications across multiple regions is fundamental to modern system neuroscience, yet current methods struggle to find time-varying region-level communications or…

Machine Learning · Computer Science 2025-08-12 Weihan Li , Yule Wang , Chengrui Li , Anqi Wu

Most brain disorders are very heterogeneous in terms of their underlying biology and developing analysis methods to model such heterogeneity is a major challenge. A promising approach is to use probabilistic regression methods to estimate…

Machine Learning · Statistics 2018-12-03 Seyed Mostafa Kia , Christian F. Beckmann , Andre F. Marquand

How much visual information about the retinal images can be extracted from the different layers of the visual pathway?. Separate subsystems (e.g. opponent channels, spatial filters, nonlinearities of the texture sensors) have been suggested…

Neurons and Cognition · Quantitative Biology 2020-05-26 Jesus Malo

Graph neural networks are often used to model interacting dynamical systems since they gracefully scale to systems with a varying and high number of agents. While there has been much progress made for deterministic interacting systems,…

Machine Learning · Computer Science 2023-05-04 Andreas Look , Melih Kandemir , Barbara Rakitsch , Jan Peters

This manuscript develops computationally efficient online learning for multivariate spatiotemporal models. The method relies on matrix-variate Gaussian distributions, dynamic linear models, and Bayesian predictive stacking to efficiently…

Methodology · Statistics 2026-02-10 Luca Presicce , Sudipto Banerjee

We aim to develop simultaneous inference tools for the mean function of functional data from sparse to dense. First, we derive a unified Gaussian approximation to construct simultaneous confidence bands of mean functions based on the…

Methodology · Statistics 2024-02-01 Leheng Cai , Qirui Hu

I overview recent research advances in Bayesian state-space modeling of multivariate time series. A main focus is on the decouple/recouple concept that enables application of state-space models to increasingly large-scale data, applying to…

Methodology · Statistics 2022-06-07 Mike West

We propose a novel approach to estimating the precision matrix of multivariate Gaussian data that relies on decomposing them into a low-rank and a diagonal component. Such decompositions are very popular for modeling large covariance…

Methodology · Statistics 2022-08-18 Noirrit Kiran Chandra , Peter Mueller , Abhra Sarkar

We introduce a scalable approach to Gaussian process inference that combines spatio-temporal filtering with natural gradient variational inference, resulting in a non-conjugate GP method for multivariate data that scales linearly with…

Machine Learning · Computer Science 2021-11-03 Oliver Hamelijnck , William J. Wilkinson , Niki A. Loppi , Arno Solin , Theodoros Damoulas

We propose a framework to analyze how multivariate representations disentangle ground-truth generative factors. A quantitative analysis of disentanglement has been based on metrics designed to compare how one variable explains each…

Machine Learning · Statistics 2022-02-11 Seiya Tokui , Issei Sato

A central question in multimodal neuroimaging analysis is to understand the association between two imaging modalities and to identify brain regions where such an association is statistically significant. In this article, we propose a…

Methodology · Statistics 2024-11-28 Moyan Li , Lexin Li , Jian Kang

Information flow provides a natural measure for the causal interaction between dynamical events. This study extends our previous rigorous formalism of componentwise information flow to the bulk information flow between two complex…

Neurons and Cognition · Quantitative Biology 2021-12-30 X. San Liang

With the significant advancement in quantum computation in the past couple of decades, the exploration of machine-learning subroutines using quantum strategies has become increasingly popular. Gaussian process regression is a widely used…

Quantum Physics · Physics 2018-03-07 Siddhartha Das , George Siopsis , Christian Weedbrook

Gaussian processes (GPs) are a powerful tool for probabilistic inference over functions. They have been applied to both regression and non-linear dimensionality reduction, and offer desirable properties such as uncertainty estimates,…

Machine Learning · Statistics 2014-10-01 Yarin Gal , Mark van der Wilk , Carl E. Rasmussen

Granger causality (GC), a popular statistical method for the inference of directional influences between time series measured from a complex network, is sensitive to high-order (non-pairwise) interactions which fundamentally shape the…

Many applications in medical statistics as well as in other fields can be described by transitions between multiple states (e.g. from health to disease) experienced by individuals over time. In this context, multi-state models are a popular…

I present a novel approach to estimating the temporal and spatial patterns of violent conflict. I show how we can use highly temporally and spatially disaggregated data on conflict events in tandem with Gaussian processes to estimate…

Machine Learning · Statistics 2025-06-10 Simon P. von der Maase

Gaussian processes allow for flexible specification of prior assumptions of unknown dynamics in state space models. We present a procedure for efficient Bayesian learning in Gaussian process state space models, where the representation is…

Computation · Statistics 2016-04-18 Andreas Svensson , Arno Solin , Simo Särkkä , Thomas B. Schön