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Measurement in biological systems became a subject of concern as a consequence of numerous reports on limited reproducibility of experimental results. To reveal origins of this inconsistency, we have examined general features of biological…

Other Quantitative Biology · Quantitative Biology 2017-04-03 Dalibor Štys , Jan Urban , Renata Rychtáriková , Anna Zhyrova , Petr Císař

Time and its lack of play a central role in our everyday lives. Despite increasing productivity, many people experience time stress, exhaustion and a longing for time affluence, and at the same time, a fear of not being busy enough. All…

Human-Computer Interaction · Computer Science 2020-04-15 Sarah Janboecke , Alina Gawlitta , Judith Doerrenbaecher , Marc Hassenzahl

Clock synchronization is a widely discussed topic in the engineering literature. Ensuring that individual clocks are closely aligned is important in network systems, since the correct timing of various events in a network is usually…

Systems and Control · Computer Science 2017-04-25 Timothy Anglea , Yongqiang Wang

Biological time can be measured in two ways: in generations and in physical (chronological) time. When generations overlap, these two notions diverge, which impedes our ability to relate mathematical models to real populations. In this…

Populations and Evolution · Quantitative Biology 2026-04-08 Kaan Öcal , Michael P. H. Stumpf

Quantum mechanics imposes a fundamental tradeoff between the accuracy of time measurements and the size of the systems used as clocks. When the measurements of different time intervals are combined, the errors due to the finite clock size…

Quantum Physics · Physics 2019-01-29 Yuxiang Yang , Giulio Chiribella , Masahito Hayashi

Ideal rods and clocks are defined as an infinitesimal symmetry of the spacetime. Since no a priori geometric structure is considered, all the possible models of spacetime are obtained.

General Relativity and Quantum Cosmology · Physics 2008-11-26 A. N. Bernal , M. P. Lopez , M. Sanchez

Many biological systems are governed by difference equations and exhibit discrete-time dynamics. Examples include the size of a population when generations are non-overlapping, and the incidence of a disease when infections are recorded at…

Populations and Evolution · Quantitative Biology 2025-09-25 Shuyun Jiao , David Waxman

Entangled states of light exhibit measurable correlations between light detections at separated locations. These correlations are exploited in entangled-state quantum key distribution. To do so involves setting up and maintaining a rhythm…

Quantum Physics · Physics 2020-04-27 F. Hadi Madjid , John M. Myers

Humans, like almost all animals, are phase-locked to the diurnal cycle. Most of us sleep at night and are active through the day. Because we have evolved to function with this cycle, the circadian rhythm is deeply ingrained and even…

Physics and Society · Physics 2015-08-03 Talayeh Aledavood , Sune Lehmann , Jari Saramäki

According to Aristotle "time is the number of change with respect to the before and after". That's certainly a vague concept, but at the same time it's both simple and satisfying from a philosophical point of view: things do not change…

History and Philosophy of Physics · Physics 2022-01-07 Marcello Poletti

Timed automata (TAs) are an extension of finite automata that can measure and react to the passage of time, providing the ability to handle real-time constraints using clocks. In 2009, Franck Cassez showed that the timed opacity problem,…

Logic in Computer Science · Computer Science 2026-03-30 Étienne André , Sarah Dépernet , Engel Lefaucheux

Causal ordering of key events in the cell cycle is essential for proper functioning of an organism. Yet, it remains a mystery how a specific temporal program of events is maintained despite ineluctable stochasticity in the biochemical…

Molecular Networks · Quantitative Biology 2017-03-30 Farshid Jafarpour , Michael Vennettilli , Srividya Iyer-Biswas

Quantum entanglement offers powerful opportunities for enhancing measurement sensitivity beyond classical limits, with optical atomic clocks serving as a leading platform for such advances. This chapter introduces the principles of…

Quantum Physics · Physics 2025-12-04 Raphael Kaubruegger , Adam M. Kaufman

Time measured by an ideal clock crucially depends on the gravitational potential and velocity of the clock according to general relativity. Technological advances in manufacturing high-precision atomic clocks have rapidly improved their…

Geophysics · Physics 2017-12-20 J. Müller , D. Dirkx , S. M. Kopeikin , G. Lion , I. Panet , G. Petit , P. N. A. M. Visser

A practical way to deal with the problem of time in quantum cosmology and quantum gravity is proposed. The main tool is effective equations, which mainly restrict explicit considerations to semiclassical regimes but have the crucial…

General Relativity and Quantum Cosmology · Physics 2011-07-20 Martin Bojowald , Philipp A Hoehn , Artur Tsobanjan

The dynamics of an unique type of clock mechanism known as grasshopper escapement is investigated with the aim of evaluating its accuracy in a noisy environment. It is demonstrated that the clock's precision scales linearly with the rate of…

Applied Physics · Physics 2022-05-11 David Ziemkiewicz

Chaos, or exponential sensitivity to small perturbations, appears everywhere in nature. Moreover, chaos is predicted to play diverse functional roles in living systems. A method for detecting chaos from empirical measurements should…

Quantitative Methods · Quantitative Biology 2020-01-13 Daniel Toker , Friedrich T. Sommer , Mark D'Esposito

Cellular phones are now offering an ubiquitous means for scientists to observe life: how people act, move and respond to external influences. They can be utilized as measurement devices of individual persons and for groups of people of the…

Physics and Society · Physics 2015-06-12 Shao-Meng Qin , Hannu Verkasalo , Mikael Mohtaschemi , Tuomo Hartonen , Mikko Alava

As a consequence of gravitomagnetism, which is a fundamental weak-field prediction of general relativity and ubiquitous in gravitational phenomena, clocks show a difference in their proper periods when moving along identical orbits in…

General Relativity and Quantum Cosmology · Physics 2007-05-23 H. Lichtenegger , W. Hausleitner , F. Gronwald , B. Mashhoon

We consider a simple cosmological model consisting of an empty Bianchi I Universe, whose Hamiltonian we deparametrise to provide a natural clock variable. The model thus effectively describes an isotropic universe with an induced clock…

General Relativity and Quantum Cosmology · Physics 2022-01-26 Przemysław Małkiewicz , Patrick Peter , S. D. P. Vitenti