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Persistent homology applied to the activity of grid cells in the Medial Entorhinal Cortex suggests that this activity lies on a toroidal manifold. By analyzing real data and a simple model, we show that neural oscillations play a key role…

Quantitative Methods · Quantitative Biology 2025-10-14 Giovanni di Sarra , Siddharth Jha , Yasser Roudi

Spiking Neural Networks (SNNs) emulate the integrated-fire-leak mechanism found in biological neurons, offering a compelling combination of biological realism and energy efficiency. In recent years, they have gained considerable research…

Neural and Evolutionary Computing · Computer Science 2024-06-06 Lihao Wang , Zhaofei Yu

Neuronal activity in the brain generates synchronous oscillations of the Local Field Potential (LFP). The traditional analyses of the LFPs are based on decomposing the signal into simpler components, such as sinusoidal harmonics. However, a…

Quantitative Methods · Quantitative Biology 2018-06-19 Luca Perotti , Justin DeVito , Daniel Bessis , Yuri Dabaghian

Spatiotemporal patterns are common in biological systems. For electrically-coupled cells previous studies of pattern formation have mainly used external forcing as the main bifurcation parameter. The purpose of this paper is to show that…

Dynamical Systems · Mathematics 2021-11-02 H. O. Fatoyinbo , R. G. Brown , D. J. W. Simpson , B. van Brunt

Synchronization is an important collective phenomenon in interacting oscillatory agents. Many functional features of the brain are related to synchronization of neurons. The type of synchronization transition that may occur (explosive vs.…

Disordered Systems and Neural Networks · Physics 2020-03-18 Mahsa Khoshkhou , Afshin Montakhab

We aim at building a bridge between to {\it a priori} disconnected fields: Neuroscience and Material Science. We construct an analogy based on identifying spikes events in time with the positions of particles of matter. We show that one may…

Neurons and Cognition · Quantitative Biology 2023-02-17 Marcelo J. Rozenberg

This paper introduces a model of excitability that unifies the mechanism of an important neuronal property both in time and in space. As a starting point, we revisit both a key model of temporal excitability, proposed by Hodgkin and Huxley,…

Systems and Control · Electrical Eng. & Systems 2025-05-29 Thomas SJ Burger , Amir Shahhosseini , Rodolphe Sepulchre

Modeling spike firing assumes that spiking statistics are Poisson, but real data violates this assumption. To capture non-Poissonian features, in order to fix the inevitable inherent irregularity, researchers rescale the time axis with…

Neural and Evolutionary Computing · Computer Science 2013-03-06 M. A. El-Dosuky , M. Z. Rashad , T. T. Hamza , A. H. EL-Bassiouny

Spike-timing dependent plasticity (STDP) is an organizing principle of biological neural networks. While synchronous firing of neurons is considered to be an important functional block in the brain, how STDP shapes neural networks possibly…

Neurons and Cognition · Quantitative Biology 2009-05-20 Yuko K. Takahashi , Hiroshi Kori , Naoki Masuda

It is assumed that the digital-like spatio-time brain activity might be caused by non-topological transformations of patterns in the cortex which is a linear, analog and active system. Such an effect can be modeled by topologically…

Computational Physics · Physics 2008-05-30 G. a. Kouzaev

This paper proposes a neuronal circuitry layout and synaptic plasticity principles that allow the (pyramidal) neuron to act as a "combinatorial switch". Namely, the neuron learns to be more prone to generate spikes given those combinations…

Biological Physics · Physics 2017-05-09 Marat M. Rvachev

Firing rate fluctuations in neural populations are observed experimentally over multiple time scales, in single neurons, across trials when elicited by stimuli, and across populations. In this work, we examine how firing rate fluctuations…

Neurons and Cognition · Quantitative Biology 2026-05-15 Wilten Nicola , Sue Ann Campbell

We designed a model-based analysis to predict the occurrence of population patterns in distributed spiking activity. Using a maximum entropy principle with a Markovian assumption, we obtain a model that accounts for both spatial and…

Neurons and Cognition · Quantitative Biology 2009-11-13 Olivier Marre , Sami El Boustani , Yves Fregnac , Alain Destexhe

Conventional modeling approaches have found limitations in matching the increasingly detailed neural network structures and dynamics recorded in experiments to the diverse brain functionalities. On another approach, studies have…

Neurons and Cognition · Quantitative Biology 2017-09-05 Chaofei Hong

We examine the effects of stochastic input currents on the firing behavior of two excitable neurons coupled with fast excitatory synapses. In such cells (models), typified by the quadratic integrate and fire model, mutual synaptic coupling…

Neurons and Cognition · Quantitative Biology 2007-07-31 Boris S. Gutkin , Juergen Jost , Henry C. Tuckwell

Cortical microcircuits are very complex networks, but they are composed of a relatively small number of stereotypical motifs. Hence one strategy for throwing light on the computational function of cortical microcircuits is to analyze…

Neurons and Cognition · Quantitative Biology 2017-05-23 Zeno Jonke , Robert Legenstein , Stefan Habenschuss , Wolfgang Maass

We posit that hippocampal place cells encode information about future locations under a transition distribution observed as an agent explores a given (physical or conceptual) space. The encoding of information about the current location,…

Machine Learning · Computer Science 2019-06-07 Mariano Tepper

How does the brain predict physical outcomes while acting in the world? Machine learning world models compress visual input into latent spaces, discarding the spatial structure that characterizes sensory cortex. We propose isomorphic world…

Neurons and Cognition · Quantitative Biology 2026-02-24 Joshua Nunley

We investigate spike-timing dependent plasticity (STPD) in the case of a synapse connecting two neural cells. We develop a theoretical analysis of several STDP rules using Markovian theory. In this context there are two different…

Neurons and Cognition · Quantitative Biology 2021-11-16 Philippe Robert , Gaëtan Vignoud

Heterogeneity of firing rate statistics is known to have severe consequences on neural coding. Recent experimental recordings in weakly electric fish indicate that the distribution-width of superficial pyramidal cell firing rates (trial-…

Neurons and Cognition · Quantitative Biology 2017-08-14 Cheng Ly , Gary Marsat