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The mean-squared displacement (MSD) is an averaged quantity widely used to assess anomalous diffusion. In many cases, such as molecular motors with finite processivity, dynamics of the system of interest produce trajectories of varying…

Statistical Mechanics · Physics 2020-10-07 Chapin S. Korosec , David A. Sivak , Nancy R. Forde

The mean square displacement and instantaneous diffusion coefficient for different configurations of charged particles in stochastic motion are calculated by numerically solving the associated equations of motion. The method is suitable for…

Statistical Mechanics · Physics 2019-06-26 Gabriela Raluca Mocanu

In parallel with advances in microscale imaging techniques, the fields of biology and materials science have focused on precisely extracting particle properties based on their diffusion behavior. Although the majority of real-world…

Mesoscale and Nanoscale Physics · Physics 2024-05-22 Kaito Takanami , Daisuke Taniguchi , Sawako Enoki , Masafumi Kuroda , Yasushi Okada , Yoshiyuki Kabashima

Macromolecular diffusion in strongly confined geometries and crowded environments is still to a large extent an open subject in soft matter physics and biology. In this paper, we employ large-scale Langevin dynamics simulations to…

Soft Condensed Matter · Physics 2020-10-07 T. P. O. Nogueira , H. O. Frota , Francesco Piazza , José Rafael Bordin

Anisotropic diffusion processes emerge in various fields such as transport in biological tissue and diffusion in liquid crystals. In such systems, the motion is described by a diffusion tensor. For a proper characterization of processes…

Data Analysis, Statistics and Probability · Physics 2013-11-14 Mario Heidernätsch , Michael Bauer , Günter Radons

In addition to enabling movement towards environments with favourable living conditions, swimming by microorganisms has also been linked to enhanced mixing and improved nutrient uptake by their populations. Experimental studies have shown…

Fluid Dynamics · Physics 2017-11-07 Blaise Delmotte , Eric E Keaveny , Eric Climent , Franck Plouraboué

Anomalous diffusion has been widely observed by single particle tracking microscopy in complex systems such as biological cells. The resulting time series are usually evaluated in terms of time averages. Often anomalous diffusion is…

Statistical Mechanics · Physics 2017-09-13 Stas Burov , Jae-Hyung Jeon , Ralf Metzler , Eli Barkai

We study the stochastic motion of active particles that undergo spontaneous transitions between two distinct modes of motion. Each mode is characterized by a velocity distribution and an arbitrary (anti-)persistence. We present an…

Statistical Mechanics · Physics 2023-07-07 M. Reza Shaebani , Heiko Rieger , Zeinab Sadjadi

Diffusion of colloidal particles in a complex environment such as polymer networks or biological cells is a topic of high complexity with significant biological and medical relevance. In such situations, the interaction between the…

Statistical Mechanics · Physics 2015-11-10 Andreas M. Menzel

In heterogeneous environments, the diffusivity is not constant but changes with time. It is important to detect changes in the diffusivity from single-particle-tracking trajectories in experiments. Here, we devise a novel method for…

Statistical Mechanics · Physics 2017-12-06 Takuma Akimoto , Eiji Yamamoto

We analyze the dynamics of an active tracer particle embedded in a thermal lattice gas. All particles are subject to exclusion up to third nearest neighbors on the square lattice, which leads to slow dynamics at high densities. For the case…

Soft Condensed Matter · Physics 2019-04-15 Rakesh Chatterjee , Nimrod Segall , Carl Merrigan , Kabir Ramola , Bulbul Chakraborty , Yair Shokef

The dynamics of a tracer particle in a bath of quasi-hard colloidal spheres is studied by Langevin dynamics simulations and mode coupling theory (MCT); the tracer radius is varied from equal to up to 7 times larger than the bath particles…

Soft Condensed Matter · Physics 2023-08-01 Francisco Orts , Manuel Maier , Matthias Fuchs , Gloria Ortega , Ester M. Garzón , Antonio M. Puertas

Volume limitations and low yield thresholds of biological fluids have led to widespread use of passive microparticle rheology. The mean-squared-displacement (MSD) statistics of bead position time series (bead paths) are either applied…

We derive equations of motion for the mean-squared displacement (MSD) of an active Brownian particle (ABP) in a crowded environment modeled by a dense system of passive Brownian particles, and of a passive tracer particle in a dense…

Soft Condensed Matter · Physics 2021-07-27 Julian Reichert , Thomas Voigtmann

By means of rather general arguments, based on an approach due to Derrida that makes use of samples of finite size, we analyse the effective diffusivity and drift tensors in certain types of random medium in which the motion of the…

Condensed Matter · Physics 2009-10-28 D S Dean , I T Drummond , R R Horgan

We perform Discrete Element Method (DEM) simulations of granular particles (polystyrene spheres) vibrated inside a cubic container. The study investigates the evolution of the packing fraction with and without rotational friction at…

Soft Condensed Matter · Physics 2026-03-03 Linnea Heitmeier , Jan Gabriel

In this work, we use the standard deviation of image pixel intensity to analyse the speed, direction and surface-interaction of microparticles in fluid. First, we present an analytical model for estimating the total variance in the image…

Applied Physics · Physics 2019-04-10 Harish Sasikumar , Manoj M. Varma

Single particle tracking of mRNA molecules and lipid granules in living cells shows that the time averaged mean squared displacement $\overline{\delta^2}$ of individual particles remains a random variable while indicating that the particle…

Statistical Mechanics · Physics 2009-11-13 Y. He , S. Burov , R. Metzler , E. Barkai

This study uses a combination of stochastic optimization, statistical mechanical theory, and molecular simulation to test the extent to which the long-time dynamics of a single tracer particle can be enhanced by rationally modifying its…

Soft Condensed Matter · Physics 2011-11-24 James Carmer , Gaurav Goel , Mark J. Pond , Jeffrey R. Errington , Thomas M. Truskett

A theoretical framework for analyzing stochastic data from single-particle tracking in complex or viscoelastic materials and under the influence of a trapping potential is presented. Starting from a generalized Langevin equation we found…

Statistical Mechanics · Physics 2010-11-22 M. A. Despósito , A. D. Viñales