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As the number of cloud platforms supporting scientific research grows, there is an increasing need to support interoperability between two or more cloud platforms, as a growing amount of data is being hosted in cloud-based platforms. A well…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-02-16 Robert L. Grossman , Rebecca R. Boyles , Brandi N. Davis-Dusenbery , Amanda Haddock , Allison P. Heath , Brian D. O'Connor , Adam C. Resnick , Deanne M. Taylor , Stan Ahalt

It is challenging to determine whether datasets are findable, accessible, interoperable, and reusable (FAIR) because the FAIR Guiding Principles refer to highly idiosyncratic criteria regarding the metadata used to annotate datasets.…

Digital Libraries · Computer Science 2022-10-17 Mark A. Musen , Martin J. O'Connor , Erik Schultes , Marcos Martinez-Romero , Josef Hardi , John Graybeal

In the ever-changing realm of research software development, it is crucial for the scientific community to grasp current trends to identify gaps that can potentially hinder scientific progress. The adherence to the FAIR (Findable,…

Software Engineering · Computer Science 2025-10-08 Eva Martín del Pico , Josep Lluís Gelpí , Salvador Capella-Gutiérrez

The increasing complexity and volume of data generated by high-throughput computational materials science require robust tools to ensure their accessibility, reproducibility, and reuse. In particular, integrating the FAIR Guiding Principles…

Materials Science · Physics 2025-10-28 Lucrezia Berghenti , Elisa Damiani , Margherita Marsili , Maria Clelia Righi

The broad sharing of research data is widely viewed as of critical importance for the speed, quality, accessibility, and integrity of science. Despite increasing efforts to encourage data sharing, both the quality of shared data, and the…

Digital Libraries · Computer Science 2022-08-30 William Dempsey , Ian Foster , Scott Fraser , Carl Kesselman

High Performance Computing (HPC) centers provide resources to users who require greater scale to "get science done". They deploy infrastructure with singular hardware architectures, cutting-edge software environments, and stricter security…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-07-22 Sean R. Wilkinson , Patrick Widener

The reuse of research software is central to research efficiency and academic exchange. The application of software enables researchers with varied backgrounds to reproduce, validate, and expand upon study findings. Furthermore, the…

Reproducibility is a cornerstone of science. FAIR (findable, accessible, interoperable, and reusable) data is often a vital step towards testing the reproducibility of results. The implementation of FAIR principles in the astrophysical…

Instrumentation and Methods for Astrophysics · Physics 2026-02-10 Susanne Pfalzner , Stephan Hachinger , Jolanta Zjupa , Salvatore Cielo , Frank W. Wagner , Marcus Brüggen , Annika Hagemeier

High Performance Computing (HPC) centers provide advanced infrastructure that enables scientific research at extreme scale. These centers operate with hardware configurations, software environments, and security requirements that differ…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-03 Sean R. Wilkinson , Patrick Widener , Sarp Oral , Rafael Ferreira da Silva

The FAIR (Findable, Accessible, Interoperable, and Reusable) data principles [1] promote the interoperability of scientific data by encouraging the use of persistent identifiers, standardized vocabularies, and formal metadata structures.…

This paper presents a portable, privacy-preserving, in-browser platform for the reproducible assessment of mutational signature detection methods from sparse sequencing data generated by targeted gene panels. The platform aims to address…

Genomics · Quantitative Biology 2023-06-05 Aaron Ge , Tongwu Zhang , Clara Bodelon , Montserrat Garcia-Closas , Jonas Almeida , Jeya Balasubramanian

The escalating cost, extended timelines, and low success rates in pharmaceutical research demand a fundamental rethinking of biotechnology R&D infrastructure. This chapter introduces the concept of the AI-Integrated Biotechnology Hub, a…

Physics and Society · Physics 2025-10-07 Alex Zhavoronkov , Chuen Yan Leung

The lack of scientific openness is identified as one of the key challenges of computational reproducibility. In addition to Open Data, Free and Open-source Software (FOSS) and Open Hardware (OH) can address this challenge by introducing…

Digital Libraries · Computer Science 2023-04-18 Nadica Miljković , Ana Trisovic , Limor Peer

Life sciences research increasingly requires identifying, accessing, and effectively processing data from an ever-evolving array of information sources on the Linked Open Data (LOD) network. This dynamic landscape places a significant…

Information Retrieval · Computer Science 2025-06-24 Syed N. Sakib , Kallol Naha , Sajratul Y. Rubaiat , Hasan M. Jamil

Open science movement has established reproducibility, transparency, and validation of research outputs as essential norms for conducting scientific research. It advocates for open access to research outputs, especially research data, to…

Digital Libraries · Computer Science 2025-04-10 Ranjeet Kumar Singh , Akanksha Nagpal , Arun Jadhav , Devika P. Madalli

The FAIR Principles are a set of good practices to improve the reproducibility and quality of data in an Open Science context. Different sets of indicators have been proposed to evaluate the FAIRness of digital objects, including datasets…

Digital Libraries · Computer Science 2023-06-28 Fernando Aguilar Gómez , Isabel Bernal

Reproducibility and replicability of research findings are central to the scientific integrity of epidemiology. In addition, many research questions require combiningdata from multiple sources to achieve adequate statistical power. However,…

Many research groups aspire to make data and code FAIR and reproducible, yet struggle because the data and code life cycles are disconnected, executable environments are often missing from published work, and technical skill requirements…

Computational methods have reshaped the landscape of modern biology. While the biomedical community is increasingly dependent on computational tools, the mechanisms ensuring open data, open software, and reproducibility are variably…

Other Quantitative Biology · Quantitative Biology 2020-07-28 Jaqueline J. Brito , Jun Li , Jason H. Moore , Casey S. Greene , Nicole A. Nogoy , Lana X. Garmire , Serghei Mangul