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A major achievement in the study of complex networks is the observation that diverse systems, from sub-cellular biology to social networks, exhibit universal topological characteristics. Yet this universality does not naturally translate to…

Physics and Society · Physics 2018-01-29 Chittaranjan Hens , Uzi Harush , Reuven Cohen , Baruch Barzel

We describe an approach to model genetic regulatory networks at the level of promotion-inhibition circuitry through a class of stochastic spin models that includes spatial and temporal density fluctuations in a natural way. The formalism…

Statistical Mechanics · Physics 2018-03-08 J. Ricardo G. Mendonça , Mário J. de Oliveira

Regulatory interactions between genes show a large amount of cross-species variability, even when the underlying functions are conserved: There are many ways to achieve the same function. Here we investigate the ability of regulatory…

Molecular Networks · Quantitative Biology 2015-05-13 Franck Stauffer , Johannes Berg

Many complex systems that exhibit temporal non-pairwise interactions can be represented by means of generative higher-order network models. Here, we propose a hidden variables formalism to analytically characterize a general class of…

Physics and Society · Physics 2024-02-12 Leonardo Di Gaetano , Federico Battiston , Michele Starnini

Novel mathematical models of three different repressilator topologies are introduced. As designable transcription factors have been shown to bind to DNA non-cooperatively, we have chosen models containing non-cooperative elements. The…

Dynamical Systems · Mathematics 2018-09-25 Masa Dukaric , Hassan Errami , Roman Jerala , Tina Lebar , Valery G. Romanovski , Janos Toth , Andreas Weber

Recent genomic and bioinformatic advances have motivated the development of numerous random network models purporting to describe graphs of biological, technological, and sociological origin. The success of a model has been evaluated by how…

Molecular Networks · Quantitative Biology 2007-05-23 Manuel Middendorf , Etay Ziv , Carter Adams , Jen Hom , Robin Koytcheff , Chaya Levovitz , Gregory Woods , Linda Chen , Chris Wiggins

The study of many-body quantum systems out of equilibrium remains a significant challenge with complexity barriers arising in both state and operator-based representations. In this work, we review recent approaches based on finding better…

Temporal networks model how the interaction between elements in a complex system evolve over time. Just like complex systems display collective dynamics, here we interpret temporal networks as trajectories performing a collective motion in…

Social and Information Networks · Computer Science 2022-10-18 Lucas Lacasa , Jorge P. Rodriguez , Victor M. Eguiluz

A repressilator consists of a loop made up of three repressively interacting genes. We construct a hexagonal lattice with repressilators on each triangle, and use this as a model system for multiple interacting feedback loops. Using…

Chaotic Dynamics · Physics 2009-09-22 Mogens H. Jensen , Sandeep Krishna , Simone Pigolotti

The collective dynamics seen in a wide variety of chemical, biological and ecological systems involve interactions between relaxation oscillators that typically involve fast activation process coupled with a slower inactivation. In this…

Pattern Formation and Solitons · Physics 2019-05-29 R. Janaki , Shakti N. Menon , Rajeev Singh , Sitabhra Sinha

Complex dynamical systems are often modeled as networks, with nodes representing dynamical units which interact through the network's links. Gene regulatory networks, responsible for the production of proteins inside a cell, are an example…

Statistical Mechanics · Physics 2009-09-30 Zoran Levnajić

This work presents some outcomes of a theoretical investigation of incompressible high-order networks defined by a generalized graph representation. We study some of their network topological properties and how these may be related to…

Information Theory · Computer Science 2019-05-15 Felipe S. Abrahão , Klaus Wehmuth , Artur Ziviani

Beyond their origin in modeling many-body quantum systems, tensor networks have emerged as a promising class of models for solving machine learning problems, notably in unsupervised generative learning. While possessing many desirable…

Machine Learning · Computer Science 2024-07-26 Alex Meiburg , Jing Chen , Jacob Miller , Raphaëlle Tihon , Guillaume Rabusseau , Alejandro Perdomo-Ortiz

Genetic regulatory networks are usually modeled by systems of coupled differential equations and by finite state models, better known as logical networks, are also used. In this paper we consider a class of models of regulatory networks…

Dynamical Systems · Mathematics 2015-06-26 Ricardo Lima , Edgardo Ugalde

Randomly connected networks of excitatory and inhibitory spiking neurons provide a parsimonious model of neural variability, but are notoriously unreliable for performing computations. We show that this difficulty is overcome by…

Neurons and Cognition · Quantitative Biology 2017-01-11 Ryan Pyle , Robert Rosenbaum

We propose a family of statistical models for social network evolution over time, which represents an extension of Exponential Random Graph Models (ERGMs). Many of the methods for ERGMs are readily adapted for these models, including…

Machine Learning · Statistics 2009-08-11 Steve Hanneke , Wenjie Fu , Eric Xing

The movement of atmospheric air masses can be seen as a continuous and complex flow of particles hovering over our planet. It can however be locally simplified by considering three-dimensional trajectories of air masses connecting distant…

Applications · Statistics 2020-07-22 Maria Choufany , Davide Martinetti , Rachid Senoussi , Cindy E. Morris , Samuel Soubeyrand

Describing a complex system is in many ways a problem akin to identifying an object, in that it involves defining boundaries, constituent parts and their relationships by the use of grouping laws. Here we propose a novel method which…

Temporal graphs represent the dynamic relationships among entities and occur in many real life application like social networks, e commerce, communication, road networks, biological systems, and many more. They necessitate research beyond…

Machine Learning · Computer Science 2022-08-26 Shubham Gupta , Srikanta Bedathur

This article proposes a method for mathematical modeling of human movements related to patient exercise episodes performed during physical therapy sessions by using artificial neural networks. The generative adversarial network structure is…

Machine Learning · Computer Science 2018-12-18 L. Li , A. Vakanski
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