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Flat-panel cone-beam CT (CBCT) has been applied clinically in a number of high-resolution applications. Increasing geometric magnification can potentially improve resolution, but also increases blur due to an extended x-ray focal-spot. We…

Medical Physics · Physics 2016-10-18 Steven Tilley , Wojciech Zbijewski , Jeffrey H. Siewerdsen , J. Webster Stayman

We present a novel reconstruction algorithm based on a general cone-beam CT forward model which is capable of incorporating the blur and noise correlations that are exhibited in flat-panel CBCT measurement data. Specifically, the proposed…

For single source helical Computed Tomography (CT), both Filtered-Back Projection (FBP) and statistical iterative reconstruction have been investigated. However for dual source CT with flying focal spot (DS-FFS CT), statistical iterative…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Xiao Wang , Robert D. MacDougall , Peng Chen , Charles A. Bouman , Simon K. Warfield

Scatter can account for large errors in cone-beam CT (CBCT) due to its wide field of view, and its complicated nature makes its compensation difficult. Iterative polyenergetic reconstruction algorithms offer the potential to provide…

Medical Physics · Physics 2020-01-13 Jonathan H. Mason , Alessandro Perelli , William H. Nailon , Mike E. Davies

The restoration of images affected by blur and noise has been widely studied and has broad potential for applications including in medical imaging modalities like computed tomography (CT). Although the blur and noise in CT images can be…

Medical Physics · Physics 2024-07-23 Yijie Yuan , Grace J. Gang , J. Webster Stayman

Image-generative artificial intelligence (AI) has garnered significant attention in recent years. In particular, the diffusion model, a core component of generative AI, produces high-quality images with rich diversity. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Sho Ozaki , Shizuo Kaji , Toshikazu Imae , Kanabu Nawa , Hideomi Yamashita , Keiichi Nakagawa

In dental cone-beam computed tomography (CBCT), compact and cost-effective system designs often use small detectors, resulting in a truncated field of view (FOV) that does not fully encompass the patient's head. In iterative reconstruction…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Hyoung Suk Park , Kiwan Jeon

The low-density imaging performance of a zone plate based nano-resolution hard X-ray computed tomography (CT) system can be significantly improved by incorporating a grating-based Lau interferometer. Due to the diffraction, however, the…

Image and Video Processing · Electrical Eng. & Systems 2023-10-16 Xuebao Cai , Yuhang Tan , Ting Su , Dong Liang , Hairong Zheng , Jinyou Xu , Peiping Zhu , Yongshuai Ge

Cone-beam computed tomography (CBCT) is routinely collected during image-guided radiation therapy (IGRT) to provide updated patient anatomy information for cancer treatments. However, CBCT images often suffer from streaking artifacts and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-02 Jiarui Zhu , Werxing Chen , Hongfei Sun , Shaohua Zhi , Jing Qin , Jing Cai , Ge Ren

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Due to its wide field of view, cone-beam computed tomography (CBCT) is plagued by large amounts of scatter, where attenuated photons hit the detector, and corrupt the linear models used for reconstruction. Given that one can generate a good…

Medical Physics · Physics 2017-07-06 Jonathan Mason , Alessandro Perelli , William Nailon , Mike Davies

Positron Emission Mammography (PEM) imaging systems with the ability in detection of millimeter-sized tumors were developed in recent years. And some of them have been well used in clinical applications. In consideration of biopsy…

Medical Physics · Physics 2016-08-03 Xiao-Yue Gu , Wei Zhou , Lin Li , Peng-Fei Yin , Lei-Min Shang , Ming-Kai Yun , Zhen-Rui Lu , Xian-Chao Huang , Long Wei

X-ray imaging dose from serial cone-beam CT (CBCT) scans raises a clinical concern in most image guided radiation therapy procedures. It is the goal of this paper to develop a fast GPU-based algorithm to reconstruct high quality CBCT images…

Medical Physics · Physics 2015-05-19 Xun Jia , Bin Dong , Yifei Lou , Steve B. Jiang

Cone-beam computed tomography (CBCT) images are problematic in clinical medicine because of their low contrast and high artifact content compared with conventional CT images. Although there are some studies to improve image quality, in…

Image and Video Processing · Electrical Eng. & Systems 2026-03-30 Naruki Murahashi , Mitsuhiro Nakamura , Megumi Nakao

Deep learning has shown impressive results in reducing noise and artifacts in X-ray computed tomography (CT) reconstruction. Self-supervised CT reconstruction methods are especially appealing for real-world applications because they require…

Image and Video Processing · Electrical Eng. & Systems 2026-05-06 Dirk Elias Schut , Adriaan Graas , Robert van Liere , Tristan van Leeuwen

Low dose CT is of great interest in these days. Dose reduction raises noise level in projections and decrease image quality in reconstructions. Model based image reconstruction can combine statistical noise model together with prior…

Medical Physics · Physics 2019-10-16 Kaichao Liang , Li Zhang , Yirong Yang , HongKai Yang , Yuxiang Xing

Lensless imaging has emerged as a potential solution towards realizing ultra-miniature cameras by eschewing the bulky lens in a traditional camera. Without a focusing lens, the lensless cameras rely on computational algorithms to recover…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Salman S. Khan , Varun Sundar , Vivek Boominathan , Ashok Veeraraghavan , Kaushik Mitra

Purpose: Cone-beam CT (CBCT) plays an important role in image guided radiation therapy (IGRT). However, the large radiation dose from serial CBCT scans in most IGRT procedures raises a clinical concern, especially for pediatric patients who…

Medical Physics · Physics 2015-05-18 Xun Jia , Yifei Lou , Ruijiang Li , William Y. Song , Steve B. Jiang

In the practical applications of computed tomography imaging, the projection data may be acquired within a limited-angle range and corrupted by noises due to the limitation of scanning conditions. The noisy incomplete projection data…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Qifeng Gao , Rui Ding , Linyuan Wang , Bin Xue , Yuping Duan

Diffusion models have been demonstrated as powerful deep learning tools for image generation in CT reconstruction and restoration. Recently, diffusion posterior sampling, where a score-based diffusion prior is combined with a likelihood…

Medical Physics · Physics 2024-09-02 Shudong Li , Xiao Jiang , Matthew Tivnan , Grace J. Gang , Yuan Shen , J. Webster Stayman
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