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Socio-technical networks represent emerging cyber-physical infrastructures that are tightly interwoven with human networks. The coupling between human and technical networks presents significant challenges in managing, controlling, and…

Systems and Control · Electrical Eng. & Systems 2024-11-07 Quanyan Zhu , Tamer Başar

The human brain is a complex network that supports mental function. The nascent field of network neuroscience applies tools from mathematics to neuroimaging data in the hopes of shedding light on cognitive function. A critical question…

Neurons and Cognition · Quantitative Biology 2017-04-26 John D. Medaglia , Perry Zurn , Walter Sinnott-Armstrong , Danielle S. Bassett

Notwithstanding the usefulness of system dynamics in analyzing complex policy problems, policy design is far from straightforward and in many instances trial-and-error driven. To address this challenge, we propose to combine system dynamics…

Physics and Society · Physics 2017-11-15 Lukas Schoenenberger , Radu Tanase

The minimum number of inputs needed to control a network is frequently used to quantify its controllability. Control of linear dynamics through a minimum set of inputs, however, often has prohibitively large energy requirements and there is…

Computational Engineering, Finance, and Science · Computer Science 2022-12-12 Samie Alizadeh , Márton Pósfai , Abdorasoul Ghasemi

We consider the problem of controlling a partially-observed dynamic process on a graph by a limited number of interventions. This problem naturally arises in contexts such as scheduling virus tests to curb an epidemic; targeted marketing in…

Machine Learning · Computer Science 2021-07-12 Eli A. Meirom , Haggai Maron , Shie Mannor , Gal Chechik

The field of optimal control typically requires the assumption of perfect knowledge of the system one desires to control, which is an unrealistic assumption for biological systems, or networks, typically affected by high levels of…

Optimization and Control · Mathematics 2021-04-28 Isaac Klickstein , Francesco Sorrentino

The concept of control is crucial for effectively understanding and applying biological network models. Key structural features relate to control functions through gene regulation, signaling, or metabolic mechanisms, and computational…

Molecular Networks · Quantitative Biology 2024-11-05 David Murrugarra , Alan Veliz-Cuba , Elena Dimitrova , Claus Kadelka , Matthew Wheeler , Reinhard Laubenbacher

Temporal networks are a class of time-varying networks, which change their topology according to a given time-ordered sequence of static networks (known as subsystems). This paper investigates the reachability and controllability of…

Systems and Control · Electrical Eng. & Systems 2024-05-27 Yuan Zhang , Yuanqing Xia , Long Wang

In this paper, we present a survey of the use of graph theoretical techniques in Biology. In particular, we discuss recent work on identifying and modelling the structure of bio-molecular networks, as well as the application of centrality…

Molecular Networks · Quantitative Biology 2007-05-23 Oliver Mason , Mark Verwoerd

In this paper, we propose a novelty-based metric for quantitative characterization of the controllability of complex networks. This inherently bounded metric describes the average angular separation of an input with respect to the past…

Optimization and Control · Mathematics 2014-09-30 Gautam Kumar , Delsin Menolascino , MohammadMehdi Kafashan , ShiNung Ching

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

Neurons and Cognition · Quantitative Biology 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett

This paper leverages linear systems theory to propose a principled measure of complexity for network systems. We focus on a network of first-order scalar linear systems interconnected through a directed graph. By locally filtering out the…

Systems and Control · Electrical Eng. & Systems 2025-07-10 Giacomo Baggio , Marco Fabris

Control theory of dynamical systems offers a powerful framework for tackling challenges in deep neural networks and other machine learning architectures. We show that concepts such as simultaneous and ensemble controllability offer new…

Optimization and Control · Mathematics 2025-12-19 Enrique Zuazua

Many complex networks display a mesoscopic structure with groups of nodes sharing many links with the other nodes in their group and comparatively few with nodes of different groups. This feature is known as community structure and encodes…

Physics and Society · Physics 2009-07-31 Andrea Lancichinetti , Santo Fortunato

To achieve control objectives for extremely large-scale complex networks using standard methods is essentially intractable. In this work a theory of the approximate control of complex network systems is proposed and developed by the use of…

Optimization and Control · Mathematics 2020-10-28 Shuang Gao , Peter E. Caines

The controllability of networked sampled-data systems with zero-order holders on the control and transmission channels is explored, where single- and multi-rate sampling patterns are considered, respectively. The effects of sampling on the…

Systems and Control · Electrical Eng. & Systems 2023-02-28 Zixuan Yang , Xiaofan Wang , Lin Wang

There is increasing interest in developing the theoretical foundations of networked control systems that illuminate how brain networks function so as to enable sensory perception, control of movement, memory and all the operations that are…

Systems and Control · Electrical Eng. & Systems 2025-06-03 Zexin Sun , John Baillieul

Optimization problems over dynamic networks have been extensively studied and widely used in the past decades to formulate numerous real-world problems. However, (1) traditional optimization-based approaches do not scale to large networks,…

Machine Learning · Computer Science 2023-05-17 Daniele Gammelli , James Harrison , Kaidi Yang , Marco Pavone , Filipe Rodrigues , Francisco C. Pereira

When designing large-scale distributed controllers, the information-sharing constraints between sub-controllers, as defined by a communication topology interconnecting them, are as important as the controller itself. Controllers implemented…

Systems and Control · Electrical Eng. & Systems 2021-04-29 Fengjun Yang , Nikolai Matni

Network controllability measures how well a networked system can be controlled to a target state, and its robustness reflects how well the system can maintain the controllability against malicious attacks by means of node-removals or…

Systems and Control · Electrical Eng. & Systems 2022-06-02 Yang Lou , Yaodong He , Lin Wang , Guanrong Chen
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