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Autoencoders offer a general way of learning low-dimensional, non-linear representations from data without labels. This is achieved without making any particular assumptions about the data type or other domain knowledge. The generality and…

Machine Learning · Computer Science 2025-05-27 Collin Leiber , Lukas Miklautz , Claudia Plant , Christian Böhm

Cryo-electron microscopy (cryo-EM) emerges as a pivotal technology for determining the architecture of cells, viruses, and protein assemblies at near-atomic resolution. Traditional particle picking, a key step in cryo-EM, struggles with…

Biomolecules · Quantitative Biology 2024-04-17 Chentianye Xu , Xueying Zhan , Min Xu

Harnessing the power of pre-training on large-scale datasets like ImageNet forms a fundamental building block for the progress of representation learning-driven solutions in computer vision. Medical images are inherently different from…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Jeya Maria Jose Valanarasu , Yucheng Tang , Dong Yang , Ziyue Xu , Can Zhao , Wenqi Li , Vishal M. Patel , Bennett Landman , Daguang Xu , Yufan He , Vishwesh Nath

Subgroup discovery is a descriptive and exploratory data mining technique to identify subgroups in a population that exhibit interesting behavior with respect to a variable of interest. Subgroup discovery has numerous applications in…

Machine Learning · Computer Science 2022-07-19 Ali Arab , Dev Arora , Jialin Lu , Martin Ester

In the effort to aid cytologic diagnostics by establishing automatic single cell screening using high throughput digital holographic microscopy for clinical studies thousands of images and millions of cells are captured. The bottleneck lies…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Julia Sistermanns , Ellen Emken , Gregor Weirich , Oliver Hayden , Wolfgang Utschick

A video autoencoder is proposed for learning disentan- gled representations of 3D structure and camera pose from videos in a self-supervised manner. Relying on temporal continuity in videos, our work assumes that the 3D scene structure in…

Computer Vision and Pattern Recognition · Computer Science 2021-10-07 Zihang Lai , Sifei Liu , Alexei A. Efros , Xiaolong Wang

Currently, analysis of microscopic In Situ Hybridization images is done manually by experts. Precise evaluation and classification of such microscopic images can ease experts' work and reveal further insights about the data. In this work,…

Image and Video Processing · Electrical Eng. & Systems 2023-12-21 Aleksandar A. Yanev , Galina D. Momcheva , Stoyan P. Pavlov

Autoencoders are widely used in machine learning applications, in particular for anomaly detection. Hence, they have been introduced in high energy physics as a promising tool for model-independent new physics searches. We scrutinize the…

High Energy Physics - Phenomenology · Physics 2021-07-15 Thorben Finke , Michael Krämer , Alessandro Morandini , Alexander Mück , Ivan Oleksiyuk

In this paper, we present a novel neuroevolutionary method to identify the architecture and hyperparameters of convolutional autoencoders. Remarkably, we used a hypervolume indicator in the context of neural architecture search for…

Neural and Evolutionary Computing · Computer Science 2021-06-23 Daniel Dimanov , Emili Balaguer-Ballester , Colin Singleton , Shahin Rostami

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Cryo-Electron Microscopy (Cryo-EM) is a Nobel prize-winning technology for determining the 3D structure of particles at near-atomic resolution. A fundamental step in the recovering of the 3D single-particle structure is to align its 2D…

Image and Video Processing · Electrical Eng. & Systems 2021-01-12 Koby Bibas , Gili Weiss-Dicker , Dana Cohen , Noa Cahan , Hayit Greenspan

Background: Single-particle cryo-electron microscopy (cryo-EM) has become a popular tool for structural determination of biological macromolecular complexes. High-resolution cryo-EM reconstruction often requires hundreds of thousands of…

Data Analysis, Statistics and Probability · Physics 2017-09-05 Yanan Zhu , Qi Ouyang , Youdong Mao

We use spatially-sparse two, three and four dimensional convolutional autoencoder networks to model sparse structures in 2D space, 3D space, and 3+1=4 dimensional space-time. We evaluate the resulting latent spaces by testing their…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Benjamin Graham

In this work we propose a novel model-based deep convolutional autoencoder that addresses the highly challenging problem of reconstructing a 3D human face from a single in-the-wild color image. To this end, we combine a convolutional…

Computer Vision and Pattern Recognition · Computer Science 2017-12-11 Ayush Tewari , Michael Zollhöfer , Hyeongwoo Kim , Pablo Garrido , Florian Bernard , Patrick Pérez , Christian Theobalt

Cryo-electron microscopy (cryo-EM), the subject of the 2017 Nobel Prize in Chemistry, is a technology for determining the 3-D structure of macromolecules from many noisy 2-D projections of instances of these macromolecules, whose…

Computer Vision and Pattern Recognition · Computer Science 2020-04-22 Roy R. Lederman , Joakim Andén , Amit Singer

Weakly-supervised anomaly detection aims at learning an anomaly detector from a limited amount of labeled data and abundant unlabeled data. Recent works build deep neural networks for anomaly detection by discriminatively mapping the normal…

Machine Learning · Computer Science 2021-08-29 Yingjie Zhou , Xucheng Song , Yanru Zhang , Fanxing Liu , Ce Zhu , Lingqiao Liu

Chromosome analysis and identification from metaphase images is a critical part of cytogenetics based medical diagnosis. It is mainly used for identifying constitutional, prenatal and acquired abnormalities in the diagnosis of genetic…

Computer Vision and Pattern Recognition · Computer Science 2022-09-13 Amritha S Pallavoor , Prajwal A , Sundareshan TS , Sreekanth K Pallavoor

To achieve reliable mining results for massive vessel trajectories, one of the most important challenges is how to efficiently compute the similarities between different vessel trajectories. The computation of vessel trajectory similarity…

Machine Learning · Computer Science 2021-06-11 Maohan Liang , Ryan Wen Liu , Shichen Li , Zhe Xiao , Xin Liu , Feng Lu

This paper presents a novel approach to learn and detect distinctive regions on 3D shapes. Unlike previous works, which require labeled data, our method is unsupervised. We conduct the analysis on point sets sampled from 3D shapes, then…

Graphics · Computer Science 2020-04-22 Xianzhi Li , Lequan Yu , Chi-Wing Fu , Daniel Cohen-Or , Pheng-Ann Heng

There are many approaches to weakly-supervised training of networks to segment 2D images. By contrast, existing approaches to segmenting volumetric images rely on full-supervision of a subset of 2D slices of the 3D volume. We propose an…

Computer Vision and Pattern Recognition · Computer Science 2022-06-06 Udaranga Wickramasinghe , Patrick M. Jensen , Mian Shah , Jiancheng Yang , Pascal Fua
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