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Neural activity fluctuates over a wide range of timescales within and across brain areas. Experimental observations suggest that diverse neural timescales reflect information in dynamic environments. However, how timescales are defined and…

Neurons and Cognition · Quantitative Biology 2026-01-21 Roxana Zeraati , Anna Levina , Jakob H. Macke , Richard Gao

Computational mechanics is a method for discovering, describing and quantifying patterns, using tools from statistical physics. It constructs optimal, minimal models of stochastic processes and their underlying causal structures. These…

Machine Learning · Computer Science 2007-05-23 Cosma Rohilla Shalizi , James P. Crutchfield

The main problem about replacing LTP as a memory mechanism has been to find other highly abstract, easily understandable principles for induced plasticity. In this paper we attempt to lay out such a basic mechanism, namely intrinsic…

Neurons and Cognition · Quantitative Biology 2014-05-13 Gabriele Scheler

When we experience an event, it feels like our previous experiences, our interpretations of that event (e.g., aesthetics, emotions), and our current state will determine how we will remember it. However, recent work has revealed a strong…

Neurons and Cognition · Quantitative Biology 2021-04-15 Wilma A. Bainbridge

Self-sustained, elevated neuronal activity persisting on time scales of ten seconds or longer is thought to be vital for aspects of working memory, including brain representations of real space. Continuous-attractor neural networks, one of…

Neurons and Cognition · Quantitative Biology 2020-08-19 Joseph L. Natale , H. George E. Hentschel , Ilya Nemenman

"You never forget how to ride a bike", -- but how is that possible? The brain is able to learn complex skills, stop the practice for years, learn other skills in between, and still retrieve the original knowledge when necessary. The…

Machine Learning · Computer Science 2024-01-26 Martin Barry , Wulfram Gerstner , Guillaume Bellec

Some visual search tasks require to memorize the location of stimuli that have been previously scanned. Considerations about the eye movements raise the question of how we are able to maintain a coherent memory, despite the frequent…

Neural and Evolutionary Computing · Computer Science 2016-08-16 Jérémy Fix , Julien Vitay , Nicolas Rougier

Storing knowledge of an agent's environment in the form of a probabilistic generative model has been established as a crucial ingredient in a multitude of cognitive tasks. Perception has been formalised as probabilistic inference over the…

Neurons and Cognition · Quantitative Biology 2018-06-22 David G. Nagy , Balázs Török , Gergő Orbán

Intelligence necessitates memory. Without memory, humans fail to perform various nontrivial tasks such as reading novels, playing games or solving maths. As the ultimate goal of machine learning is to derive intelligent systems that learn…

Machine Learning · Computer Science 2021-07-06 Hung Le

We consider a lifelong learning scenario in which a learner faces a neverending and arbitrary stream of facts and has to decide which ones to retain in its limited memory. We introduce a mathematical model based on the online learning…

Machine Learning · Computer Science 2022-01-13 Robi Bhattacharjee , Gaurav Mahajan

Memory is the fundamental form of temporal complexity: when present but uncontrollable, it manifests as non-Markovian noise; conversely, if controllable, memory can be a powerful resource for information processing. Memory effects arise…

Quantum Physics · Physics 2024-05-07 Philip Taranto , Marco Túlio Quintino , Mio Murao , Simon Milz

We have recognized that 2D codes, i.e., a group of strongly connected neurosomes that can be simultaneously excited, are the basic data carriers for memory in a brain. An echoing mechanism between two neighboring layers of neurosomes is…

Neurons and Cognition · Quantitative Biology 2017-11-15 Shengyong Xu , Jingjing Xu

Making neural networks remember over the long term has been a longstanding issue. Although several external memory techniques have been introduced, most focus on retaining recent information in the short term. Regardless of its importance,…

Machine Learning · Computer Science 2024-07-19 Sangjun Park , JinYeong Bak

Short-term memory is essential for cognitive processing, yet our understanding of its neural mechanisms remains unclear. Neuroscience has long focused on how sequential activity patterns, where neurons fire one after another within large…

The ongoing exponential rise in recording capacity calls for new approaches for analysing and interpreting neural data. Effective dimensionality has emerged as an important property of neural activity across populations of neurons, yet…

Neurons and Cognition · Quantitative Biology 2021-08-30 Mehrdad Jazayeri , Srdjan Ostojic

We present an account of neuroplasticity with respect to cell-internal processing pathways in relation to membrane and synaptic plasticity. We think traditional synapse-centric, weight-based models of memorization are not sufficient or…

Neurons and Cognition · Quantitative Biology 2026-04-27 Gabriele Scheler

Synaptic plasticity dynamically shapes the connectivity of neural systems and is key to learning processes in the brain. To what extent the mechanisms of plasticity can be exploited to drive a neural network and make it perform some kind of…

Neurons and Cognition · Quantitative Biology 2024-12-03 Francesco Borra , Simona Cocco , Rémi Monasson

One of the central aims of neuroscience is to reliably predict the behavioral response of an organism using its neural activity. If possible, this implies we can causally manipulate the neural response and design brain-computer-interface…

Neurons and Cognition · Quantitative Biology 2025-04-01 Jayanth R Taranath

The thesis explores the role machine learning methods play in creating intuitive computational models of neural processing. Combined with interpretability techniques, machine learning could replace human modeler and shift the focus of human…

Neurons and Cognition · Quantitative Biology 2020-10-20 Ilya Kuzovkin

Late long-term potentiation (L-LTP) appears essential for the formation of long-term memory, with memories at least partly encoded by patterns of strengthened synapses. How memories are preserved for months or years, despite molecular…

Neurons and Cognition · Quantitative Biology 2015-05-13 Paul Smolen