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Objective: The objective of this study is to develop a machine learning (ML)-based framework for early risk stratification of clinical trials (CTs) according to their likelihood of exhibiting a high rate of dosing errors, using information…

Machine Learning · Computer Science 2026-02-27 Félicien Hêche , Sohrab Ferdowsi , Anthony Yazdani , Sara Sansaloni-Pastor , Douglas Teodoro

The existence of large volumes of time series data in many applications has motivated data miners to investigate specialized methods for mining time series data. Clustering is a popular data mining method due to its powerful exploratory…

Machine Learning · Computer Science 2016-08-04 Fateme Fahiman , Jame C. Bezdek , Sarah M. Erfani , Christopher Leckie , Marimuthu Palaniswami

Currently, data-driven discovery in biological sciences resides in finding segmentation strategies in multivariate data that produce sensible descriptions of the data. Clustering is but one of several approaches and sometimes falls short…

Quantitative Methods · Quantitative Biology 2022-08-12 Richard Tjörnhammar

PURPOSE To develop free-running multi-echo GRE for cardiac- and respiratory-motion-resolved whole-heart fat fraction quantification. METHODS Multi-echo readouts optimized for water-fat separation and quantification were integrated within a…

Deep learning based methods for automatic organ segmentation have shown promise in aiding diagnosis and treatment planning. However, quantifying and understanding the uncertainty associated with model predictions is crucial in critical…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Jadie Adams , Shireen Y. Elhabian

Risk stratification (characterization) of tumors from radiology images can be more accurate and faster with computer-aided diagnosis (CAD) tools. Tumor characterization through such tools can also enable non-invasive cancer staging,…

Computer Vision and Pattern Recognition · Computer Science 2019-01-21 Sarfaraz Hussein , Pujan Kandel , Candice W. Bolan , Michael B. Wallace , Ulas Bagci

Fuzzy clustering has become a widely used data mining technique and plays an important role in grouping, traversing and selectively using data for user specified applications. The deterministic Fuzzy C-Means (FCM) algorithm may result in…

Neural and Evolutionary Computing · Computer Science 2018-10-23 Saptarshi Sengupta , Sanchita Basak , Richard Alan Peters

Identifying groups that share common features among datasets through clustering analysis is a typical problem in many fields of science, particularly in post-omics and systems biology research. In respect of this, quantifying how a measure…

Masked Image Modeling (MIM) methods, like Masked Autoencoders (MAE), efficiently learn a rich representation of the input. However, for adapting to downstream tasks, they require a sufficient amount of labeled data since their rich features…

Computer Vision and Pattern Recognition · Computer Science 2023-09-15 Johannes Lehner , Benedikt Alkin , Andreas Fürst , Elisabeth Rumetshofer , Lukas Miklautz , Sepp Hochreiter

Multi-Energy Computed Tomography (ME-CT) is a medical imaging modality aiming to reconstruct the spatial density of materials from the attenuation properties of probing x-rays. For each line in two- or three-dimensional space, ME-CT…

Numerical Analysis · Mathematics 2020-06-24 Guillaume Bal , Fatma Terzioglu

Structural health monitoring (SHM) relies on non-destructive techniques such as acoustic emission (AE) that generate large amounts of data over the lifespan of systems. Clustering methods are used to interpret these data and gain insights…

This paper describes a method for overlap-aware speaker diarization. Given an overlap detector and a speaker embedding extractor, our method performs spectral clustering of segments informed by the output of the overlap detector. This is…

Audio and Speech Processing · Electrical Eng. & Systems 2020-11-06 Desh Raj , Zili Huang , Sanjeev Khudanpur

Centroid-based methods including k-means and fuzzy c-means are known as effective and easy-to-implement approaches to clustering purposes in many applications. However, these algorithms cannot be directly applied to supervised tasks. This…

Machine Learning · Computer Science 2021-04-20 Pooya Ashtari , Fateme Nateghi Haredasht , Hamid Beigy

Identifying relationships between molecular variations and their clinical presentations has been challenged by the heterogeneous causes of a disease. It is imperative to unveil the relationship between the high dimensional molecular…

Methodology · Statistics 2021-09-02 Wennan Chang , Changlin Wan , Yong Zang , Chi Zhang , Sha Cao

Spatial clustering techniques can achieve significant multi-channel noise reduction across relatively arbitrary microphone configurations, but have difficulty incorporating a detailed speech/noise model. In contrast, LSTM neural networks…

Sound · Computer Science 2020-12-07 Zhaoheng Ni , Felix Grezes , Viet Anh Trinh , Michael I. Mandel

Magnetic resonance imaging (MRI) is indispensable for diagnosing and planning treatment in various medical conditions due to its ability to produce multi-series images that reveal different tissue characteristics. However, integrating these…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Churan Wang , Fei Gao , Lijun Yan , Siwen Wang , Yizhou Yu , Yizhou Wang

Current massive datasets demand light-weight access for analysis. Discrete hashing methods are thus beneficial because they map high-dimensional data to compact binary codes that are efficient to store and process, while preserving semantic…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Yunqiang Li , Wenjie Pei , Yufei zha , Jan van Gemert

The impact of an extreme climate event depends strongly on its geographical scale. Max-stable processes can be used for the statistical investigation of climate extremes and their spatial dependencies on a continuous area. Most existing…

Methodology · Statistics 2023-06-14 Justus Contzen , Thorsten Dickhaus , Gerrit Lohmann

Clustering algorithms remain valuable tools for grouping and summarizing the most important aspects of data. Example areas where this is the case include image segmentation, dimension reduction, signals analysis, model order reduction,…

Numerical Analysis · Mathematics 2024-12-24 Guy B. Oldaker , Maria Emelianenko

This paper addresses the limitations of conventional vector quantization algorithms, particularly K-Means and its variant K-Means++, and investigates the Stochastic Quantization (SQ) algorithm as a scalable alternative for high-dimensional…

Machine Learning · Computer Science 2025-03-11 Anton Kozyriev , Vladimir Norkin