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Tremor is a key diagnostic feature of Parkinson's Disease (PD), Essential Tremor (ET), and other central nervous system (CNS) disorders. Clinicians or trained raters assess tremor severity with TETRAS scores by observing patients. Lacking…
Parkinson's disease (PD) affects over ten million people worldwide. Although temporal interference (TI) and deep brain stimulation (DBS) are promising therapies, inter-individual variability limits empirical treatment selection, increasing…
The midline related pathological image features are crucial for evaluating the severity of brain compression caused by stroke or traumatic brain injury (TBI). The automated midline delineation not only improves the assessment and clinical…
This paper presents a novel method to automatically identify late-activating regions of the left ventricle from cine Displacement Encoding with Stimulated Echo (DENSE) MR images. We develop a deep learning framework that identifies late…
One of the most catastrophic neurological disorders worldwide is Parkinson's Disease. Along with it, the treatment is complicated and abundantly expensive. The only effective action to control the progression is diagnosing it in the early…
Electroencephalography (EEG) allows for source measurement of electrical brain activity. Particularly for inverse localization, the electrode positions on the scalp need to be known. Often, systems such as optical digitizing scanners are…
About 5-8% of individuals over the age of 60 have dementia. With our ever-aging population this number is likely to increase, making dementia one of the most important threats to public health in the 21st century. Given the phenotypic…
Diagnosis of Parkinson's disease (PD) is commonly based on medical observations and assessment of clinical signs, including the characterization of a variety of motor symptoms. However, traditional diagnostic approaches may suffer from…
As the second most common neurodegenerative disease, Parkinson's disease has caused serious problems worldwide. However, the cause and mechanism of PD are not clear, and no systematic early diagnosis and treatment of PD have been…
Parkinson's disease (PD) is a slowly progressing neurodegenerative disease with early manifestation of motor signs. Recently, there has been a growing interest in developing automatic tools that can assess motor function in PD patients.…
In this paper we present an efficient model of the neuronal potentials recorded by a deep brain stimulation microelectrode (DBS MER) in the subthalamic nucleus. It is shown that a computationally efficient filtered point process consisting…
This study investigates EEG as a potential early biomarker by applying deep learning techniques to resting-state EEG recordings from 31 subjects (15 with PD and 16 healthy controls). EEG signals underwent preprocessing to remove tremor…
Epilepsy is a common neurological disorder characterized by recurrent seizures accompanied by excessive synchronous brain activity. The process of structural and functional brain alterations leading to increased seizure susceptibility and…
Parkinson's disease (PD) is a common neurodegenerative disorder that severely diminishes patients' quality of life. Its global prevalence has increased markedly in recent decades. Current diagnostic workflows are complex and heavily reliant…
This work considers the optimization of electrode positions in head imaging by electrical impedance tomography. The study is motivated by maximizing the sensitivity of electrode measurements to conductivity changes when monitoring the…
One major challenge in the medication of Parkinson's disease is that the severity of the disease, reflected in the patients' motor state, cannot be measured using accessible biomarkers. Therefore, we develop and examine a variety of…
Transcranial Electrical Stimulation (tES) is a neuromodulation technique that utilizes electrodes on the scalp to stimulate target brain regions. tES has shown promise in treating many neurological conditions, such as stroke rehabilitation…
Deep Brain Stimulation (DBS) is effective in treating neurological disorders but involves invasive surgery. Non-invasive DBS aims to overcome surgical risks by means of externally applied electromagnetic fields. In this work, we present a…
Introduction: Multiple Sclerosis (MS) is a chronic disease that affects millions of people across the globe. MS can critically affect different organs of the central nervous system such as the eyes, the spinal cord, and the brain.…
The detection of human sleep stages is widely used in the diagnosis and intervention of neurological and psychiatric diseases. Some patients with deep brain stimulator implanted could have their neural activities recorded from the deep…