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During the spreading of epithelial tissues, the advancing tissue front often develops fingerlike protrusions. Their resemblance to traditional viscous fingering patterns in driven fluids suggests that epithelial fingers could arise from an…

Biological Physics · Physics 2019-03-05 Ricard Alert , Carles Blanch-Mercader , Jaume Casademunt

Motivated by studies suggesting that the patterns exhibited by the collectively expanding fronts of thin cells during the closing of a wound [Mark et al., Biophys. J., 98:361-370, 2010] and the shapes of single cells crawling on surfaces…

Soft Condensed Matter · Physics 2018-03-14 Amarender Nagilla , Ranganathan Prabhakar , Sameer Jadhav

The invasion of one fluid into another of higher viscosity in a quasi-two dimensional geometry typically produces complex fingering patterns. Because interfacial tension suppresses short-wavelength fluctuations, its elimination by using…

Fluid Dynamics · Physics 2015-06-23 Irmgard Bischofberger , Radha Ramachandran , Sidney R. Nagel

From the mitotic spindle up to tissues and biofilms, many biological systems behave as active droplets, which often break symmetry and change shape spontaneously. Here, I show that active nematic droplets can experience a fingering…

Soft Condensed Matter · Physics 2022-06-07 Ricard Alert

Treating the epithelium as an incompressible fluid adjacent to a viscoelastic stroma, we find a novel hydrodynamic instability that leads to the formation of protrusions of the epithelium into the stroma. This instability is a candidate for…

Biological Physics · Physics 2012-03-09 Markus Basan , Jean-Francois Joanny , Jacques Prost , Thomas Risler

Metastatic tumors often invade healthy neighboring tissues by forming multicellular finger-like protrusions emerging from the cancer mass. To understand the mechanical context behind this phenomenon, we here develop a minimalist fluid model…

Biological Physics · Physics 2018-09-18 Michał Bogdan , Thierry Savin

We experimentally study the viscous fingering instability in a fluid-fluid phase separated colloid-polymer mixture by means of laser scanning confocal microscopy and microfluidics. We focus on three aspects of the instability. (i) The…

We study theoretically the edge fracture instability in sheared complex fluids, by means of linear stability analysis and direct nonlinear simulations. We derive an exact analytical expression for the onset of edge fracture in terms of the…

Soft Condensed Matter · Physics 2017-07-19 Ewan J. Hemingway , Halim Kusumaatmaja , Suzanne M. Fielding

We perform a detailed theoretical study of the edge fracture instability, which commonly destabilises the fluid-air interface during strong shear flows of entangled polymeric fluids, leading to unreliable rheological measurements. By means…

Soft Condensed Matter · Physics 2019-07-25 Ewan J. Hemingway , Suzanne M. Fielding

The displacement of a more viscous fluid by a less viscous one in a quasi-two dimensional geometry leads to the formation of complex fingering patterns. This fingering has been characterized by a most unstable wavelength, $\lambda_c$, which…

Fluid Dynamics · Physics 2015-01-30 Irmgard Bischofberger , Radha Ramachandran , Sidney R. Nagel

Viscous flows in a quasi-two-dimensional Hele-Shaw geometry can lead to an interfacial instability when one fluid, of viscosity $\eta_{in}$ displaces another of higher viscosity, $\eta_{out}$. Recent studies have shown that there is a delay…

Soft Condensed Matter · Physics 2017-04-11 Radha Ramachandran

The onset of viscous fingering in the presence of a non monotonic viscosity profile is investigated theoretically for two immiscible fluids. Classical fluid dynamics predicts that no unstable behavior may be observed when a viscous fluid…

Fluid Dynamics · Physics 2024-03-18 Vicente Pérez-Muñuzuri

Collective cell migration plays a crucial role in many developmental processes that underlie morphogenesis, wound healing, or cancer progression. In such coordinated behaviours, cells are organised in coherent structures and actively…

Soft Condensed Matter · Physics 2021-06-16 Carolina Trenado , Luis L. Bonilla , Alejandro Martínez-Calvo

Hydrodynamic instabilities in miscible fluids are ubiquitous, from natural phenomena up to geological scales, to industrial and technological applications, where they represent the only way to control and promote mixing at low Reynolds…

Soft Condensed Matter · Physics 2017-12-21 Domenico Truzzolillo , Luca Cipelletti

When a liquid viscous bridge between two parallel substrates is stretched by accelerating one substrate, its interface recedes in the radial direction. In some cases the interface becomes unstable. Such instability leads to the emergence of…

Fluid Dynamics · Physics 2019-12-05 Sebastian Brulin , Ilia V. Roisman , Cameron Tropea

When a fluid is pumped into a cavity in a confined elastic layer, at a critical pressure, destabilizing fingers of fluid invade the elastic solid along its meniscus (Saintyves, Dauchot, and Bouchaud, 2013). These fingers occur without…

Soft Condensed Matter · Physics 2015-06-11 J. S. Biggins , Z. Wei , L. Mahadevan

Two laboratory scale experiments of dry and under-water avalanches of non-cohesive granular materials are investigated. We trigger solitary waves and study the conditions under which the front is transversally stable. We show the existence…

Soft Condensed Matter · Physics 2009-11-11 F. Malloggi , J. Lanuza , B. Andreotti , E. Clément

The spreading of a thin film of suspension on a spinning disk and the accompanying contact line instability is studied through flow visualization experiments. The critical radius for the onset of instability shows an increase with increase…

Soft Condensed Matter · Physics 2016-06-10 Mayuresh Kulkarni , Subhadarshinee Sahoo , Pankaj Doshi , Ashish V. Orpe

The process of one fluid pushing another is universally common while involving complex interfacial instabilities. Particularly, occurring in a myriad of natural and industrial processes, wavy fingering patterns frequently emerge when a less…

Fluid Dynamics · Physics 2022-05-18 Alban Pouplard , Peichun Amy Tsai

Fingering instabilities akin to the Rayleigh-Taylor (RT) instability in fluids have been observed in a binary granular system consisting of dense and small particles layered on top of lighter and larger particles, when the system is…

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