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Multiple lines of evidence strongly suggest that infection hotspots, where a single individual infects many others, play a key role in the transmission dynamics of COVID-19. However, most of the existing epidemiological models fail to…

Susceptible-Infected-Recovered (SIR) models have been used for decades to understand epidemic outbreak dynamics. We develop an SIR model specifically designed to study the effects of population behavior with respect to health and…

Populations and Evolution · Quantitative Biology 2023-08-03 Jasmin Nunuvero , Angelique Santiago , Moshe Cohen , Anca Radulescu

Traditional epidemic models consider that individual processes occur at constant rates. That is, an infected individual has a constant probability per unit time of recovering from infection after contagion. This assumption certainly fails…

Populations and Evolution · Quantitative Biology 2013-03-18 Guillermo Abramson , Sebastian Gonçalves , Marcelo F. C. Gomes

This paper is concerned with SIR (susceptible $\to$ infected $\to$ removed) household epidemic models in which the infection response may be either mild or severe, with the type of response also affecting the infectiousness of an…

Probability · Mathematics 2010-05-26 Frank Ball , Tom Britton , David Sirl

Traditional biomedical approaches treat diseases in isolation, but the importance of synergistic disease interactions is now recognized. As a first step we present and analyze a simple coinfection model for two diseases affecting…

Dynamical Systems · Mathematics 2015-04-21 Marcos Marvá , Ezio Venturino , Rafael Bravo de la Parra

During an infectious disease outbreak, providing accurate answers to policy questions about transmission requires a detailed model of the natural history of infectiousness. Unfortunately, direct measures of infectiousness are generally…

In most models of the spread of disease over contact networks it is assumed that the probabilities per unit time of disease transmission and recovery from disease are constant, implying exponential distributions of the time intervals for…

Physics and Society · Physics 2010-07-23 Brian Karrer , M. E. J. Newman

Heterogeneity is an important property of any population experiencing a disease. Here we apply general methods of the theory of heterogeneous populations to the simplest mathematical models in epidemiology. In particular, an SIR…

Populations and Evolution · Quantitative Biology 2012-02-28 Artem S Novozhilov

In this paper, we consider a discrete-time stochastic SIR model, where the transmission rate and the true number of infectious individuals are random and unobservable. An advantage of this model is that it permits us to account for random…

Physics and Society · Physics 2024-01-30 Katia Colaneri , Camilla Damian , Rüdiger Frey

This document is the Part IV of the book 'Stochastic Epidemic Models with Inference' edited by Tom Britton and Etienne Pardoux. It is written by Catherine Lar\'edo, with the contribution of Viet Chi Tran for the Chapter 4. Epidemic data…

Probability · Mathematics 2020-04-17 Catherine Larédo , Viet Chi Tran

This paper proposes a novel discrete-time multi-virus susceptible-infected-recovered (SIR) model that captures the spread of competing epidemics over a population network. First, we provide sufficient conditions for the infection level of…

Systems and Control · Electrical Eng. & Systems 2023-05-17 Ciyuan Zhang , Sebin Gracy , Tamer Basar , Philip E. Pare

The study of infectious disease propagation is essential for understanding and controlling epidemics. One of the most useful tools for gaining insights into the spread of infectious diseases is mathematical modelling. In terms of…

We introduce a modified SIR model with memory for the dynamics of epidemic spreading in a constant population of individuals. Each individual is in one of the states susceptible (${\bf S}$), infected (${\bf I}$) or recovered (${\bf R}$). In…

Populations and Evolution · Quantitative Biology 2022-03-03 Michael Bestehorn , Thomas M. Michelitsch , Bernard A. Collet , Alejandro P. Riascos , Andrzej F. Nowakowski

We propose a generative model and an inference scheme for epidemic processes on dynamic, adaptive contact networks. Network evolution is formulated as a link-Markovian process, which is then coupled to an individual-level stochastic SIR…

Methodology · Statistics 2020-04-07 Fan Bu , Allison E. Aiello , Jason Xu , Alexander Volfovsky

The paper presents an algorithm for syndromic surveillance of an epidemic outbreak formulated in the context of stochastic nonlinear filtering. The dynamics of the epidemic is modeled using a generalized compartmental epidemiological model…

Quantitative Methods · Quantitative Biology 2011-10-24 Alex Skvortsov , Branko Ristic

The issue of state estimation is considered for an SIR-SI epidemiological model describing a vector-borne disease such as dengue fever, subject to seasonal variations. Assuming continuous measurement of the incidence rate (that is the…

Optimization and Control · Mathematics 2018-03-08 Maria Soledad Aronna , Pierre-Alexandre Bliman , Maria Aronna

Deterministic compartmental models have been used extensively in modeling epidemic propagation. These models are required to fit available data and numerical procedures are often implemented to this end. But not every model architecture is…

Populations and Evolution · Quantitative Biology 2021-11-23 Gabriel Turinici

Contagious processes, such as spread of infectious diseases, social behaviors, or computer viruses, affect biological, social, and technological systems. Epidemic models for large populations and finite populations on networks have been…

Optimization and Control · Mathematics 2020-04-14 Renato Pagliara , Naomi E. Leonard

What role do asymptomatically infected individuals play in the transmission dynamics? There are many diseases, such as norovirus and influenza, where some infected hosts show symptoms of the disease while others are asymptomatically…

Populations and Evolution · Quantitative Biology 2018-01-29 Ka Yin Leung , Pieter Trapman , Tom Britton

We present a model of contagion that unifies and generalizes existing models of the spread of social influences and micro-organismal infections. Our model incorporates individual memory of exposure to a contagious entity (e.g., a rumor or…

Physics and Society · Physics 2017-06-01 Peter Sheridan Dodds , Duncan J. Watts